Provided is a diagnostic system including: a user terminal configured to take an image; and a server configured to obtain diagnosis assistance information on the basis of the image. The user terminal is configured to obtain a first photographing parameter, determine whether a pre-stored condition is satisfied, and transmit the first photographing parameter and a captured image to the server when it is determined that the pre-stored condition is satisfied. The server is configured to obtain a first verification parameter, determine whether to use the captured image as a diagnostic image which includes comparing the first verification parameter with the first photographing parameter, and obtain the diagnosis assistance information by using the diagnostic image when it is determined to use the captured image as the diagnostic image.

A combined auto-fluorescence imaging and laser speckle contrast imaging (LSCI) system to enable intra-operative parathyroid identification and viability assessment with the same tool. The system includes a light source for emitting a beam of light to illuminate a target of interest, and an imaging head positioned over the target of interest for individually acquiring auto-fluorescence images and LSCI images of light from the illuminated target of interest responsive to the illumination. Auto-fluorescence imaging helps identify the parathyroid, while LSCI helps assess its viability.

Provided is a method and apparatus for providing information needed for the diagnosis of lymph node metastasis of a thyroid cancer, and the method includes the steps of: acquiring medical images produced correspondingly to the continuous volumes of a body region including the neck; detecting at least one or more lymph nodes from the medical images through a first network function learned, the lymph nodes including at least one or more lymph nodes having higher lymph node metastasis risks than a given reference value; dividing the neck tissue around the thyroid into a plurality of compartments on the medical images through a second network function learned, based on the anatomical characteristics of the neck tissue; and matching diagnostic information including the information of the detected lymph nodes and the plurality of compartments with the medical images and displaying the diagnostic information on the medical images.

Provided is a obtaining an excitation-emission matrix, wherein the excitation-emission matrix is measured with a spectrometer by: illuminating a biological tissue with stimulant light at a first wavelength to cause a first fluorescent emission of light by the biological tissue, measuring a first set of intensities of the first fluorescent emission of light at a plurality of different respective emission wavelengths, illuminating the biological tissue with stimulant light at a second wavelength to cause a second fluorescent emission of light by the biological tissue, and measuring a second set of intensities of the second fluorescent emission of light at a plurality of different respective emission wavelengths; and inferring a classification of the biological tissue or a concentration of a substance in the biological tissue with a multi-layer neural network or other machine learning model.

According to the present application, a computer-implemented method of predicting thyroid eye disease is disclosed. The method comprising: preparing a conjunctival hyperemia prediction model, a conjunctival edema prediction model, a lacrimal edema prediction model, an eyelid redness prediction model, and an eyelid edema prediction model, obtaining a facial image of an object, obtaining a first processed image and a second processed image from the facial image, wherein the first processed image is different from the second processed image, obtaining predicted values for each of a conjunctival hyperemia, a conjunctival edema and a lacrimal edema by applying the first processed image to the conjunctival hyperemia prediction model, the conjunctival edema prediction model, and the lacrimal edema prediction model, and obtaining predicted values for each of an eyelid redness and an eyelid edema by applying the second processed image to the eyelid redness prediction model and the eyelid edema prediction model.

Provided are a system and a computer program for managing and predicting thyrotoxicosis using a wearable device. The system for predicting thyrotoxicosis is a system for predicting thyrotoxicosis using a resting heart rate, the system including a wearable device for measuring the heart rate of a patient at regular intervals, and a bio-signal computing device for receiving heart rate information from the wearable device, the bio-signal computing device outputting a warning alarm when a resting heart rate is greater than a reference heart rate when the patient is in a normal state.

According to the present application, a computer-implemented method of predicting thyroid eye disease is disclosed. The method comprising: preparing a conjunctival hyperemia prediction model, a conjunctival edema prediction model, a lacrimal edema prediction model, an eyelid redness prediction model, and an eyelid edema prediction model, obtaining a facial image of an object, obtaining a first processed image and a second processed image from the facial image, wherein the first processed image is different from the second processed image, obtaining predicted values for each of a conjunctival hyperemia, a conjunctival edema and a lacrimal edema by applying the first processed image to the conjunctival hyperemia prediction model, the conjunctival edema prediction model, and the lacrimal edema prediction model, and obtaining predicted values for each of an eyelid redness and an eyelid edema by applying the second processed image to the eyelid redness prediction model and the eyelid edema prediction model.

One aspect of the invention relates to a method for intraoperative detection of parathyroid gland viability in a surgery, comprising obtaining speckle contrast images of a parathyroid gland of a patent; and displaying the speckle contrast images of the parathyroid gland in real-time.

According to the present application, a computer-implemented method of predicting thyroid eye disease is disclosed. The method comprising: preparing a conjunctival hyperemia prediction model, a conjunctival edema prediction model, a lacrimal edema prediction model, an eyelid redness prediction model, and an eyelid edema prediction model, obtaining a facial image of an object, obtaining a first processed image and a second processed image from the facial image, wherein the first processed image is different from the second processed image, obtaining predicted values for each of a conjunctival hyperemia, a conjunctival edema and a lacrimal edema by applying the first processed image to the conjunctival hyperemia prediction model, the conjunctival edema prediction model, and the lacrimal edema prediction model, and obtaining predicted values for each of an eyelid redness and an eyelid edema by applying the second processed image to the eyelid redness prediction model and the eyelid edema prediction model.

A method of obtaining user information to analyze a Clinical Activity Score (CAS) of a user is provided. The method includes providing a guidance on a photographing device to indicate a proper position of at least one eye of the user, obtaining a facial image of the user in response to satisfying predetermined conditions. The facial image comprises at least one eye of the user. The predetermined conditions includes 1) whether a position of at least one eye is on a predetermined region, 2) whether a degree of rotation of a face of the user is within a predetermined range, 3) whether a degree of the user's smile is the same or less than a first predetermined value, and 4) whether a degree of ambient brightness is the same or less than a second predetermined value. The method further includes outputting inquiries on the photographing device, and obtaining user input.