A61B5/4227

Systems and methods for peripheral nervous stimulation for metabolic and endocrine function

Systems and methods are provided for neuro stimulation. In one implementation, a system is provided that includes a stimulator introduced into tissue at a target location and a central controller that communicates wirelessly with the stimulator. The stimulator includes a power system that receives wireless energy transmission, and an electrode system that transmits an electrical pulse for stimulating the target location. The central controller includes a power system that wirelessly delivers power to the stimulator, a communication system that wirelessly communicates with the stimulator, and a processing system that controls the power system and the communication system. The central controller may instruct the stimulator to transmit one or more electrical pulses to the target location to affect an endocrine function (e.g., affect the glucose level of a patient).

Ex Vivo and In Vivo Systems for Evaluating Hemostatic Patches, Sealants, Adhesives on Solid Organs

The present is directed to systems for ex vivo testing performance of a hemostatic or sealing product attached to an animal organ and fully covering a cored channel in said organ, comprising: a pressure sensor positioned proximate to said hemostatic or sealing product in said cored channel; a monitoring or recording device configured to receive pressure readings from said pressure sensor; and a pressurized fluid source connected to said cored channel and configured to supply said pressurized fluid into said cored channel under constant or variable pressure. The present invention is also directed to methods of use for such systems.

TREATMENT OF PSYCHIATRIC CONDITIONS SUCH AS RESISTANT DEPRESSION, BIPOLAR DISORDER AND/OR MAJOR DEPRESSIVE DISORDER VIA APPLICATION OF REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION WITH THYROID HORMONE TREATMENT AND/OR QUETIAPINE
20200384279 · 2020-12-10 · ·

The present invention relates to treatment of a psychiatric condition, for example resistant depression (RD), bipolar disorder (either threshold or sub-threshold) and/or major depressive disorder via application of repetitive transcranial magnetic stimulation with a drug treatment, in particular application of repetitive transcranial magnetic stimulation with treatment to modulate the activity of the neurones and induce neuroplasticity and the use of Thyroid hormone treatment to increase quantity or activity of thyroid hormones, for example for treatment of thyroid dysfunction. Patients may be selected for treatment by testing for the presence of normal thyroid function.

REAL-TIME PARATHYROID SENSING SYSTEM

The present invention relates to a parathyroid sensing system, and includes: a modulator for generating a modulation signal having a predetermined frequency; a lock-in amplifier and a light source which receive information on the modulation signal; an excitation filter for transmitting, among light emitted from the light source, only excitation light that excites parathyroid glands; an emission filter connected to a probe and selectively transmitting only fluorescence emitted from the parathyroid glands; a near-infrared sensor for sensing the autofluorescence that has passed through the emission filter, and converting the sensed autofluorescence into an electric signal; and a speaker for generating an alarm through the electric signal. Through the present invention, the locations of the parathyroid glands may be precisely identified even when lights are turned on in an operating room, and convenience may be provided by alerting a surgeon by means of an alarm when the parathyroid glands are detected. In addition, the locations of the parathyroid glands may be precisely detected, even when the probe is not directly in contact with the parathyroid glands, by using the autofluorescence characteristics of the parathyroid glands.

APPARATUS, SYSTEMS AND METHODS FOR MONITORING AND EVALUATING CARDIOPULMONARY FUNCTIONING

A system for monitoring the cardiopulmonary functioning of a person includes a remote terminal and a sensor module configured to be worn by the person. The sensor module includes at least one physiological sensor configured to sense the following types of physiological information generated by the person: pulse rate, blood flow, and blood pressure; at least one signal processor configured to process signals generated by the at least one physiological sensor; and at least one transmitter responsive to the at least one signal processor that is configured to transmit at least one signal to the at least one remote terminal. The at least one signal processor is configured to focus processing resources on one of the types of physiological information in response to a specified preference by the person.

Physiological method to regulate Immune and Endocrinal systems to cure Cancers, blood and neurological diseases.
20200315520 · 2020-10-08 ·

The Invention of a method of Closing an Orifice located right behind the Epiglottis under the vocal cords unlocks the keys of Immune System and adjusts the Endocrine system. This Orifice is responsible of letting Saliva streaming abnormally into capillaries to imbue them with extra water and inhibiting digested nutrients of Plasma to enter capillaries due to deregulation of Starling Forces. A phenomenon that damages capillaries membranes by creating perforations and reducing the functioning capacity of the lymphatic system and T, B and NK Cells, responsible of enhancing the Immune System. Closing this Orifice will drain out Extra water (Saliva) of capillaries and regulate Starling forces to enable nutrients to enter bloodstream and to increase cells Metabolism, regulate hormones secretion, enable the maturation of NK cells to kill cancers, regulate blood sugar, regulate blood pressure, repair brain's neurons and reproduce new cells to replace defected ones.

TISSUE DETECTION SYSTEM AND METHODS FOR USE THEREOF
20200305696 · 2020-10-01 ·

A tissue detection system and methods for use thereof are provided. The tissue detection system facilitates stimulating fluorescence via illumination in an area or areas of interest in the human body, detecting non-visible or not easily visible areas of interest subject to such stimulation, and identifying these areas of interest efficiently. The tissue detection system can employ a probe for facilitating illumination/stimulation of a tissue of interest, at least one emitter for generating radiation applied to the tissue of interest, and at least one detector for capturing radiation for the fluorescing tissues of interest.

REAL-TIME PARATHYROID IMAGING SYSTEM

The present invention relates to a real-time parathyroid imaging apparatus including: a light source including an excitation filter capable of exciting parathyroid glands; and a camera including an image sensor and an emission filter of which a transmissivity ratio between a visible light region and a near-infrared emission wavelength region is N:1 (here, N<1). Through the present invention, a system may be implemented whereby a surgeon may acquire, in real-time during an operation, an autofluorescence image of the parathyroid glands by using a near-infrared light source, and an auto focus function may be used, and visible light and near-infrared autofluorescence images may be simultaneously fused and acquired without having to turn off the lights in an operating room.

NONINVASIVE, MULTISPECTRAL-FLUORESCENCE CHARACTERIZATION OF BIOLOGICAL TISSUES WITH MACHINE/DEEP LEARNING
20200268252 · 2020-08-27 ·

Provided is a obtaining an excitation-emission matrix, wherein the excitation-emission matrix is measured with a spectrometer by: illuminating a biological tissue with stimulant light at a first wavelength to cause a first fluorescent emission of light by the biological tissue, measuring a first set of intensities of the first fluorescent emission of light at a plurality of different respective emission wavelengths, illuminating the biological tissue with stimulant light at a second wavelength to cause a second fluorescent emission of light by the biological tissue, and measuring a second set of intensities of the second fluorescent emission of light at a plurality of different respective emission wavelengths; and inferring a classification of the biological tissue or a concentration of a substance in the biological tissue with a multi-layer neural network or other machine learning model.

Systems and methods for obesity diagnosis and/or treatment

A system for treating a gastrointestinal tract may include a device configured to measure electrical activity at a plurality of locations within a gastrointestinal tract of a patient, a controller configured to compare the measured activity from the plurality of locations to a database of electrical activity corresponding to one or more gastric events, abnormalities, or dysrhythmias. The controller may be configured to determine one or more treatment locations based on the comparison, and cause the device to deliver therapy to the one or more treatment locations.