There is provided herein a system and a method for an insertion device positioning guidance system comprising: an electromagnetic field generator configured to generate an electromagnetic field covering a treatment area; a plate sensor configured to be positioned within the treatment area in a location defining an orientation of a subject; a reference sensor configured to be positioned, within the treatment area, on the subject's torso, the reference sensor is configured to define a reference coordinate system representing the position and orientation of the subject's torso relative to said field generator; a registration sensor configured to mark at least a first and a second anatomic locations relative to the reference coordinate system; and a processor configured to operate said field generator, read signals obtained from said the plate sensor, said reference sensor and said registration sensor, calculate a position and orientation thereof relative to said field generator, generate a 3D anatomic map representing the torso of the subject and the first and second anatomic locations, said processor is further configured to facilitate visualization on the 3D anatomic map of a position, orientation and/or path of a tip sensor, located in a distal tip section of the insertion device, with respect to the first and second anatomic locations, independent of the subject's movement and independent of deviations in the position and/or orientation of said field generator, thus determination of a successful medical procedure is facilitated.

Systems and methods for measuring and monitoring intracavitary tissue temperature. The system may include a catheter shaft with a circuit board disposed therein, the circuit board having an array of sensors disposed thereon. The catheter shaft may have an opening and an expandable structure surrounding the opening to provide a field of view of the intracavitary tissue for the array of sensors through the opening. The system may include a software-based programming system run on a computer such that a clinician may review information indicative of temperature of the intracavitary tissue, and be alerted if the temperature exceeds a predetermined threshold.

A system and a method for an insertion device positioning guidance system comprising: an electromagnetic field generator configured to generate an electromagnetic field covering a treatment area; a plate sensor configured to be positioned within the treatment area in a location defining an orientation of a subject; a reference sensor configured to be positioned, within the treatment area, on the subject's torso, the reference sensor is configured to define a reference coordinate system representing the position and orientation of the subject's torso relative to said field generator; a registration sensor configured to mark at least a first and a second anatomic locations relative to the reference coordinate system; and a processor configured to operate said field generator, read signals obtained from said the plate sensor, said reference sensor and said registration sensor, calculate a position and orientation thereof relative to said field generator, generate a 3D anatomic map representing the torso of the subject and the first and second anatomic locations, said processor is further configured to facilitate visualization on the 3D anatomic map of a position, orientation and/or path of a tip sensor, located in a distal tip section of the insertion device, with respect to the first and second anatomic locations, independent of the subject's movement and independent of deviations in the position and/or orientation of said field generator, thus determination of a successful medical procedure is facilitated.

A manometric catheter probe includes a flexible printed circuit, one or more pressure sensor assemblies coupled to the flexible printed circuit along a length of the flexible printed circuit, and a first flexible sleeve. Each pressure sensor assembly includes a body. The body includes a central cavity configured to receive the flexible printed circuit and an annular recess of the body. Each pressure sensor assembly further includes a microelectromechanical systems (MEMS) sensor disposed in the annular recess, an electrical connector configured to electrically couple the MEMS sensor and the flexible printed circuit, and a first flexible sleeve disposed over the annular recess of the body. The first flexible sleeve includes a fluid configured to communicate pressure to the MEMS sensor, and a second sleeve is disposed over the pressure sensor assembly.

Measurements of esophageal pressure and geometry are classified using a trained machine learning algorithm, such as a neural network or other classifier algorithm. Contractile response patterns can be identified in the esophageal pressure and geometry data, from which classified feature data can be generated. The classified feature data classify the esophageal pressure and geometry data as being indicative of an upper gastrointestinal disorder in the subject.

The present invention relates to a system (1; 1A) for use in connection with mechanical ventilation of a patient (3), provided by a ventilator (5). The system comprises a sensor arrangement (7; 7A; 7B) configured to register at least one signal (S.sub.LP; S.sub.LP(TA), S.sub.LP(CT); S.sub.e1-5; S.sub.e11-12), herein referred to as LP signal, related to muscular activity of at least one muscle (17, 19) in the laryngopharyngeal region (9) of said patient (3). Furthermore, the system comprises at least one control unit (11; 11A, 11B) configured to control the operation of said ventilator (5) based on said at least one LP signal, and/or to cause display of information related to said at least one LP signal on a display unit (13A, 13B) for monitoring said patient (3) and/or the operation of the ventilator (5).

Apparatus and associated methods relate to diagnostic device and system including a proximal balloon disposed along a length of a catheter and a distal balloon disposed at a distal end of the catheter, with at least one camera disposed at the distal balloon and a pH sensor deployable via inflation of the proximal balloon and configured to engage a patient's esophagus wall to attach the pH sensor to the patient's esophagus wall. In an illustrative example, the pH sensor may be releasably retained to the catheter adjacent to the proximal balloon. The pH sensor may include a tissue engaging feature configured to engage a patient's esophagus wall to attach the pH sensor to the patient's esophagus wall. The diagnostic device may improve upon existing processes by providing a single device to perform a multi-purpose diagnostic procedure.

A medical device with closed-loop responsive stimulation may include techniques to mitigate the impact on the therapy output of noise coupled into the medical device. A medical device according to this disclosure may determine the presence of noise and alter the closed loop policy to provide the necessary therapy to the patient and avoid prolonged under stimulation caused by the noise. The medical device may continue therapy while testing for noise. When the device determines the noise level no longer affects the output therapy, the device may return the closed loop policy to a no-noise mode of operation. The medical device may also include techniques to mitigate the impact of manual adjustment while the medical device is subject to noise or is responding to changes in the patient's physiological signals.

An esophageal monitoring device includes a camera and, optionally, one or more lights to enable visualization of an interior of a subject's esophagus. Visualization of the interior of the subject's esophagus before and after a left atrial ablation procedure may enable a healthcare provider to determine whether or not the left atrial ablation procedure has damaged the subject's esophagus before the subject experiences any symptoms of such damage. An esophageal monitoring device may also include sensors and/or markers that enable a determination of its location within a subject's esophagus. Such an esophageal monitoring device may be configured for three-dimensional mapping, and enable the generation of an accurate three-dimensional map of the physical relationship between a subject's esophagus and the left atrium of his or her heart. Methods of monitoring a subject's esophagus while a left atrial ablation procedure is being conducted on the subject's hear are also disclosed.

Methods and apparatus for guiding medical care based on sensor data from the gastrointestinal tract are described utilizing an apparatus which can be used with enteral feeding. Generally, the apparatus includes an elongated body having a length configured for insertion into a stomach and at least one pair of electrodes located along the length of the elongated body and positionable for placement within the stomach. A controller in electrical communication with the at least one pair of electrodes is included and the control may also be configured to measure a conductivity or impedance between the pair of electrodes and to determine a gastric residual volume of the stomach based on the measured conductivity or impedance.