An ingestible capsule arranged, in use, to cross a human stomach for carrying out a phototherapeutic treatment arranged to combat an infection due to the presence of the bacterium Helicobacter pylori, the ingestible capsule comprising at least one primary light source arranged to emit an electromagnetic phototherapeutic wave having a wavelength λ.sub.1, at least one auxiliary light source arranged to emit an electromagnetic phototherapeutic wave having a wavelength λ.sub.2, a wrapper arranged to contain the or each primary light source and the or each auxiliary light source, the wrapper being at least partially transparent to the wavelengths λ.sub.1, and λ.sub.2, a control unit arranged to selectively activate the or each primary light source and/or the or each auxiliary light source.

The invention discloses a bidirectional ultrasonic capsule for gastrointestinal measurement. The capsule comprises pairs of ultrasonic ranging probes to obtain correlated depth or morphology data of two sides of an inner wall of a digestive tract, wherein Probe 1 is configured to range a first distance to a first side of the inner wall of the digestive tract along a first direction and Probe 2 is configured to range a second distance to a second side of the inner wall of the digestive tract along an opposite direction to the first direction, and data of the first and second distances are correlated and a sum of the first distance, the second distance and a third distance between Probe 1 and Probe 2 is obtained as a directional cavity diameter of the digestive tract, which eliminates errors caused by motion of the capsule in the digestive tract in the unidirectional measurement of the prior art.

An apparatus for determining a position of an object inside a body includes a first, detector configured to receive a signal from the object inside the body. The apparatus also includes a camera configured to capture an image or video of outside of a portion of the body, The object is positioned inside the portion of the body. A computing system is configured to receive the signal from the first detector and the image or video from the camera and to determine the position of the object Inside the body. A screen, is configured to display die position of the object inside the body.

Disclosed is an NGT system, the system comprises a nasogastric tube having a diameter and length configured to pass through an esophagus such that the lumen of the NGT maintains fluid communication with a portion of the digestive tract, and a digestive tract sensor operatively associated with the NGT, the digestive tract sensor configured to sense from inside the body and transmit signals in response to one or both of conditions relating to nourishment states of the digestive tract, and positioning of the NGT.

An ingestible device is disclosed which can produce spectral data of one or more analytes, as well as associated methods for characterizing the gastrointestinal tract of a subject which contains such analytes. Related kits and systems are also disclosed.

The present invention relates to a capsule-type endoscope assembly which can be assembled or disassembled in a digestive organ of an examinee, and a capsule-type endoscope system using same. A capsule-type endoscope of the present invention can be actively operated by application of an external magnetic field. In addition, according to the present invention, after an examinee has separately swallowed various diagnosis and treatment devices modularized according to a purpose of diagnosis and treatment, the diagnosis and treatment devices can be assembled in a digestive organ of the examinee. Therefore, a function of a capsule-type endoscope can be extended to various diagnosis and treatment areas conventionally covered by a conventional general endoscope.

Embodiments provide devices, systems and methods for measuring a gastric emptying (GE) parameter (GEP). Many embodiments provide a swallowable capsule having three electrodes one covered by a coating which remains in the stomach but is degraded in the small intestine (SI). The electrodes are coupled to circuitry such that when the capsule is in the stomach, current flow occurs between the first two electrodes generating a first signal and in the SI current flow occurs between the second and now uncovered third electrode generating a second signal. These two signals can be transmitted and analyzed externally or by an internal controller to determine a GEP e.g., GE time. The patient may wear an external device configured to receive and analyze the signals to determine GE time. Embodiments of the invention may be used to diagnose gastroparesis and provide patient's information on when to eat meals or administer insulin after eating.

A nasogastric probe comprises at least one substantially flexible tubular element of elongated shape, provided with at least one main channel communicating with at least one feeding mouth of nutritive substances or the like, which is arranged at a first end stretch of the tubular element itself, and with at least one delivery mouth of nutritive substances or the like, which is arranged at a second end stretch opposed to the first end stretch and intended to be inserted into the patient's stomach passing through the esophagus; and it comprises pressure detecting means inside the esophagus comprising at least one pressure sensor associated with the tubular element and interposed between the feeding mouth and the delivery mouth.

Systems and methods are provided for monitoring a user having a chronic gastrointestinal indication. A questionnaire regarding a plurality of conditions is provided on a repeating basis. Each such condition at least partly arises from the gastrointestinal indication. Questionnaire questions are each associated with a corresponding condition and provide an affordance that allows the user to select between low and high values in accordance with user association with the condition. Responses are stored in a data store associated with the user. A user requested report comprising a graphical quality of life measure of the user is provided based upon temporal questionnaire answers. Questionnaire information is communicated to a remote device for medical practitioner evaluation and computation of a temporal overall quality of life score based on a plurality of component quality of life scores, each of which is associated with a condition in the plurality of conditions.

A soft, stretchable, multifunctional bioelectronic interface can be used to monitor and/or modulate an entire organ, such as a stomach, heart, bladder, or spinal cord. The interface's softness translates to reduced mechanical mismatch with the tissue, and the interface's stretchability reduces interfacial stress with dynamically expanding and contracting organs. The electronics are stretchable thanks in part to liquid-metal conductors sealed within hollow channels of elastomeric fibers embedded in the interface. The liquid metal is largely strain-insensitive, non-toxic, and has a melting point of less than 37° C., so it remains liquid when implanted in a mammalian body. The liquid metal conductors connect microelectronic components, such as micro light-emitting diodes (μLEDs), electrodes, photodiodes, and temperature sensors, to a flexible printed circuit board (fPCB) at one end of the fiber. The interface may include other microelectronic components, such as piezoelectric strain sensors, that are also coupled to the fPCB.