A method is provided for generating images using a MRI system. The method includes one or more acts below. First, the MRI system applies a pulse sequence to obtain a first set of blood oxygenation level dependent (BOLD) MRI images of a pregnant subject during a first time period. The MRI system then applies the pulse sequence to obtain a second set of BOLD MRI images of the pregnant subject during a second time period. The MRI system automatically extracts one or more regions of interest that include a placenta of the pregnant subject in the first and second sets of BOLD MRI images. The MRI system obtains BOLD signal changes in the one or more regions of interest based on the first and second sets of BOLD MRI images. The MRI system generates, based on the BOLD signal changes, a map indicating placental oxygen transport.

Methods and apparatus to form a biometric based information communication system are described. In some examples, the biometric based information communication system comprises biomedical devices with sensing means, wherein the sensing means produces a biometric result. In some examples the biometric based information communication system may comprise a user device such as a smart phone paired in communication with the biomedical device. A biometric measurement result may trigger a communication of a biometric based information communication message.

Methods, systems, and devices for miscarriage identification are described. A system may be configured to receive physiological data associated with a user that is pregnant and collected over a plurality of days, where the physiological data includes at least temperature data. Additionally, the system may be configured to determine a time series of temperature values. The system may then identify that the temperature values are lower than a pregnancy baseline of temperature values for the user and detect an indication of an early pregnancy loss of the user. The system may generate a message for display on a graphical user interface on a user device that indicates the indication of the early pregnancy loss.

A method comprising: acquiring via a network biogas information representing a concentration of 2-ethylhexanoic acid of the user acquired by a sensor that detects the 2-ethylhexanoic acid discharged from a skin surface of the user; obtaining the reference information representing a lower limit of a normal range of the concentration of 2-ethylhexanoic acid per unit period of time, using a memory storing the reference information; and outputting information related to stress of the user an information terminal of the user, after it is determined that a frequency that concentration of the 2-ethylhexanoic acid of the user per the unit period of time is less than the lower limit of the normal range tends to increase, based on the biogas information acquired in a pregnancy period of the user.

Aspects of embodiments pertain to a perineal protection device for reducing the risk or preventing perineal tear during birth. The device may comprise a reinforcement shield that is releasably connectable to a female perineum of a subject, the reinforcement shield having a surface geometry substantially corresponding to an underlying perineal muscle structure and being configured to reduce deformation of the perineum during childbirth. Optionally, the perineal protection device further comprises a fastener arrangement for releasably securing the reinforcement shield to the female perineum. The fastener arrangement may comprise a support pad that is adhesively engageable with the subject and/or straps for strapping the reinforcement shield to the subject.

Provided herein are methods and kits for determining receptivity status of an endometrium for embryonic implantation.

A method and device for measuring intra-abdominal pressure in a pregnant woman to assess likelihood or occurrence of pre-eclampsia. The method includes providing a catheter having first and second lumens and a balloon, inserting the catheter into a bladder of the patient, injecting gas into the first lumen of the catheter to expand the balloon, obtaining a first pressure reading of the bladder based on deformation of the balloon to thereby monitor pressure within an abdomen of the mother to assess if pre-eclampsia is occurring or likely to occur and transmitting the first pressure reading to an external monitor connected to the catheter. The pressure reading is indicative of the presence and/or risk of pre-eclampsia to determine when intervention should occur to prevent morbidity and mortality of the woman and baby.

Systems and methods are provided for assigning a quality parameter to a reproductive cellular structure. An image of the reproductive cellular structure is obtained. The image of the reproductive cellular structure is provided to a neural network to generate a value representing a morphology of the reproductive cellular structure. The value is compared to a predefined standard to provide a quality assurance metric representing one of a medical personnel, a facility, a growth medium, and an identity of the reproductive cellular structure.

Methods and system are described for multi-modal, multi-parametric, non-invasive, and real-time assessment of cervical tissue through a multi-modal probe device for use within a vaginal canal and an associated imaging system to assess a risk of preterm delivery of an expectant mother. The multi-modal system may include ultrasound (US) imaging, viscoelastic (VE) imaging, and/or photoacoustic (PA) imaging of the cervical issue to determine cervical biomarker information indicative of parameters including, but not limited to, a collagen to water ratio such that a more water dominant ratio is indicative of a risk of preterm delivery.

A system for non-invasively detecting changes in human tissues, the system comprising: an Electrical Impedance Tomography (EIT) sensor capable of acquiring readings associated with a group of human tissues of a patient; and a processing resource configured to: obtain reference state information based on a reference EIT reading obtained at a past time, the reference state information being indicative of a reference state of the group of human tissues; acquire, using the EIT sensor, a current reading; analyze the current EIT reading to determine current state information indicative of a current state of the group of human tissues; compare the reference state information with the current state information to determine a change between the reference state of the group of human tissues and the current state of the group of human tissues; and provide output indicative of the change, or lack thereof, to a user of the system.