A driver for transperineal magnetic resonance elastography provides a body harness stabilizing a mechanical actuator against a body reference point to provide improved imaging. The driver may employ a polymer bellows for mechanical simplicity and low cost.

A system for controlled neuromodulation procedures is disclosed. A system for controlled micro ablation procedures is disclosed. Systems and methods for imaging, monitoring, stimulating, and/or ablating neurological structures coupled to one or more organs of the lower urinary tract (LUT) are disclosed. Such processes may be used to alter the hormonal secretions from one or more organs, to modulate the growth of an organ, alter the growth rate or rate of perineural invasion of a tumor, or the like. In particular such processes may be used to slow, halt and/or reverse the growth of a prostate gland or a prostate tumor.

The present invention relates to methods and kits for radiolabelling a chelate-functionalized targeting agent with a metal radionuclide being gallium-68, using a stabiliser that prevents radiolysis (product degradation) of the chelate-functionalized targeting agent, wherein said stabiliser is selected from the group consisting of: ascorbic acid, dehydroascorbic acid, gentisic acid, cysteine and methionine, sodium ascorbate, or a salt thereof, preferably as a solution. The invention further relates to the use of said stabilizer against radiolytic decomposition of a radiolabelled chelate-functionalized targeting agent composition and methods of detecting a prostate tumour or cancer using the method for radiolabelling.

A prostate cancer diagnosis system and method for predicting prostate cancer by digitally converting tactile sensations of a user is proposed, and according to the proposed system and method, the system is configured to include a prostate cancer measurement device configured to visualize the tactile sensation as an image by using electrodes applied according to changes in elasticity of prostate tissue to which pressure is applied, and a mobile device configured to receive visualized prostate tactile sensation numerical data from the prostate cancer measurement device, analyze presence or absence of the tissue on the basis of the prostate tactile sensation numerical data, and diagnose the prostate cancer through a result of analyzing the numerical data, so as to output the diagnosis, wherein palpation of the prostate cancer can be caused by using a small tactile sensor and easy diagnosis of an early-stage prostate nodule is possible without relying on experts.

A large language model-based medical examination conclusion generation method includes: obtaining a target manifestation text corresponding to a target medical examination; extracting medical examination inference knowledge that matches the target manifestation text from a medical examination inference knowledge base, where the medical examination inference knowledge includes a manifestation text and a conclusion text corresponding to a medical examination; constructing a sample based on the extracted medical examination inference knowledge, and constructing a prompt text based on the sample and the target manifestation text; and inputting the prompt text into a large language model, and outputting, by using the large language model, a target conclusion text that corresponds to the target medical examination and that is obtained by performing inference based on the target manifestation text and under guidance of the sample.

A system for assessing cancer includes a memory configured to store one or more images of tissue of a patient, where the one or more images originate from a magnetic resonance imaging (MRI) machine. The system also includes a processor operatively coupled to the memory and configured to determine a composition of the tissue. The processor is also configured to determine, based at least in part on the composition of the tissue, an apparent diffusion constant of the tissue. The processor is also configured to identify a region of cancer based at least in part on the apparent diffusion constant. The processor is further configured to generate a map that identifies the region of cancer in the tissue.

Systems and methods are provided herein that generally involve measuring a prostate or other object. In some embodiments, a finger clip having a roller ring or wheel rotatably mounted thereto is disposed within an inflatable membrane. The roller ring can include a measurement pattern positioned opposite to optical fibers configured to receive light reflected from the measurement pattern. A user can put on the finger clip, position the membrane in proximity to a rectal wall overlying a prostate, and inflate the membrane. As the user slides their finger across the inside of the membrane, which is pressed against the rectal wall, the roller ring can rotate with respect to the fibers such that the fibers move relative to the measurement pattern. A controller can sense light reflected through the fibers from the reference pattern and calculate or estimate various attributes of the prostate based on the reflected light.

A method of producing cytopathologic cell samples, the method including insonating a target tissue by ultrasound energy with a focused beam at that generates shear waves within the tissue. A method of producing cytopathologic cell samples, the method including insonating a target tissue by ultrasound energy at a first intensity level during a first period, insonating the target tissue by ultrasound energy at a second intensity level during a second period, wherein the first intensity level is higher than the second intensity level. Related apparatus and methods are also described.

Systems, methods, and computer programs disclosed herein relate to prostate cancer local staging based on multi-parametric magnetic resonance imaging images using a trained machine learning model.