A strain sensor unit and a skin sensor module comprising the same are provided. The strain sensor unit according to an embodiment of the present disclosure includes a substrate having a through-hole, and including a first electrode and a second electrode formed at one side and the other side of the through-hole on one surface of the substrate, a piezoelectric device drawn from the first electrode and extending inward the through-hole, and a piezoresistor drawn from the second electrode and extending inward the through-hole, wherein the piezoresistor overlaps with a whole or part of the piezoelectric device.

The present disclosure relates to a system (1) for remote assessment of a patient (P1), comprising: a first device (2) associated to a physician (P2), a second device (3) associated to the patient (P1), a medical device (4) associated to the patient (P1), wherein the second device (3) is configured to communicate with the medical device (4), and wherein the medical device (4) is configured to be programmed via the second device (3), wherein the first device (2) is further configured to communicate with the second device (3), and wherein the second device (3) is configured to be controlled via the first device (2), and wherein the second device (3) is configured to acquire data (S1, S2) indicative of at least one physiological parameter or of several physiological parameters (HR, F, P) of the patient (P1). Furthermore, a method for remote assessment is provided.

A method for measuring skin thickness. The method includes at a first 3D point on an outer surface of a patient, exposing the first point to near infrared (NIR) energy from an NIR source. The method includes measuring reflected energy emanating near the first 3D point, or beam incident point. The method includes determining a pattern of the reflected energy based on a distance from a center of the reflected energy, wherein the center is approximated by the first 3D point. The method includes determining a skin thickness measurement based on the pattern.

A system having a scope with a longitudinal length extending between a proximal end and a distal end includes a plurality of markers spaced along the longitudinal length. The system also includes a disassociation and positioning device that is configured to enhance unsedated transnasal endoscopic procedures by at least partially occluding the vision of a patient while enabling body cavity access, and optionally record and sense body functions such as temperature, heart rate and oxygenation of the blood stream. The system further includes a sensor integrated into the distraction device, wherein the sensor is configured to detect the markers on the longitudinal length of the scope.

A system, devices, and methods are described for imaging and measuring the mechanical properties of both surface and subcutaneous tissues found in living organisms, animals, and in natural and synthetic materials, and may include a first device configured to determine a modulus of a portion of bulk material or subcutaneous tissue (via measurement of vibrations), and/or determine resonant frequency of the vibrations, and a second device operably connected to the first device and configured to generate vibrations. The first device may be an optical coherence tomography device. The system may include a processor and data storage device with instructions which when executed by the processor, cause the processor to process of the frequency data and the displacement data to determine a resonant frequency of the material under investigation and calculate the mechanical modulus of elasticity of the material from a resonance frequency spectrum of the analyzed spectral image.

A method to provide skin care treatment is provided. The method includes receiving, by an electrical stimulator apparatus, programmable instructions from an external device for a skin care treatment. The electrical stimulator apparatus delivers an electric current to an area of skin through a plurality of electrodes. The electric current is controlled based on the skin care treatment. The external device presents guidance corresponding with the skin care treatment. The guidance is configured to aid a user in operating the electrical stimulator apparatus.

A method for the objective determination of capillary refill behavior on a human body surface in which a spatially and spectrally resolved optical detection is carried out by at least one detector device (1) at a skin surface area (2) having a predefined areal size and outer contour. Subsequently a predefined pressure p constant over the skin surface area (2) is exerted over a predefined time t1; and the pressure effect is ended after expiry of this time t1. The spatially and spectrally resolved optical detection is carried out by the detector device (1) and the respective capillary refill behavior is spatially and temporally determined at a time t2 up to which at least one first threshold value of the measurement values detected simultaneously with spatial resolution has reached the measurement value that had been optically detected before the start of the pressure effect.

Methods and systems for providing depth-resolved real-time visual feedback to a physician during cosmetic dermal filler injections with micrometer spatial resolution utilizing a noninvasive optical coherence tomography/elastography, 2D-3D virtual and real time system. This system can be automated to direct proper volumes and viscosity of the necessary injection substances. The methods and systems allow for assessment of the elasticity of the tissue before and after the injection to evaluate the efficacy of the injection, with predetermined virtual results before and matched post injection images. The elasticity assessment method preferably utilizes a focused air-pulse to induce a micrometer scale displacement in the skin and the optical coherence tomography system to image this displacement. By utilizing a model-based reconstruction method, the viscoelasticity of the tissue at a specific measurement position can be obtained and virtual and post injection real time projections can be imaged.

Tissue surface tracking of tissue features is disclosed. First surface imaged features are tracked based on the first and second time spaced images at a first wavelength. Second surface imaged features are tracked based on the first and second time spaced tissue surface images at the second wavelength. Tracking metrics are obtained based on the tracking steps. The tracking steps are combined to provide a combined tracking metric. The combined tracking metric is used in a tissue surface navigation application.

Example inventions are directed to the repairing of a wrinkle area. Example inventions affix a patch externally on a dermis of a user so that the patch extends over the wrinkle area of the user, the patch comprising a flexible substrate, a processor directly coupled to the substrate, and electrodes directly coupled to the substrate. Example inventions activate the patch to initiate a treatment session, the activating comprising generating electrical stimuli via the electrodes that is directed at the wrinkle area.