The present disclosure provides an optical palpation device for evaluating a mechanical property of a sample material. The device comprises a body having a sensing portion and a sensing layer positioned at the sensing portion of the body and having a sensing surface positioned for direct or indirect contact with a surface area of the sample material. The sensing layer is deformable and has a predetermined deformation-dependent optical property. The device further comprises a light detector positioned to detect light transmitted through at least a portion of the sensing layer. The optical palpation device is arranged such that, when the sensing surface of the sensing layer is in direct or indirect contact with the surface area of the sample material and a pressure is applied through both the sensing layer and at least a portion of the surface area of the sample material, because of the predetermined deformation or pressure-dependent optical property of the sensing layer the mechanical property of the sample material is measurable by detecting the light that transmitted through at least a portion of the sensing layer.

The thickness of a tissue layer is calculated using optical measurements from a wearable physiological monitor. In general, a modele.g., an analytical, empirical, or statistical modelcan be created that interrelates distance from a light source (directed into the skin from the surface), light intensity, and tissue thickness. With this model, a suitable light source can be directed into skin, and measurements of light intensity at various distances along the surface of the skin from the light source can be used to calculate thickness of a tissue layer in a multi-layer structure such as the dermis over layers of fat, muscle, bone, and the like. Changes in dermal thickness can be tracked over time, and used to assess a user's health or fitness. The thickness can also support an evaluation of other characteristics such as dermis elasticity, e.g., tracking over time and correlating to health, hydration, and so forth.

A display device includes display pixels arranged in a display area of a display panel, infrared light emitting pixels arranged in the display area to alternate with the display pixels, light sensing pixels arranged in the display area to alternate with the infrared light emitting pixels, a display scan driver supplying display scan signals to the display pixels and the infrared light emitting pixels, a light sensing driver sequentially supplying sensing scan signals to the light sensing pixels, and a component detection circuit for analyzing biomarker information using light sensing signals received from the light sensing pixels, which are based on light reflected from an object in front of the display panel.

Digital imaging systems and methods are described for analyzing pixel data of an image of a skin area of a user for determining skin puffiness. A plurality of training images of a plurality of individuals are aggregated, each of the training images comprising pixel data of a respective skin area of an individual. A skin puffiness model, trained with the pixel data, is operable to output, across a range of a skin puffiness scale, skin puffiness values associated with a degree of skin puffiness. An image of a user comprising pixel data of at least a portion of a user skin area is received and analyzed, by the skin puffiness model, to determine a user-specific skin puffiness value of the user skin area. A user-specific electronic recommendation addressing at least one feature identifiable within the pixel data is generated and rendered, on a display screen of a user computing device.

Apparatus are provided for monitoring a condition of a tissue based on a measurement of an electrical property of the tissue. In an example, the electrical property of the tissue is performed using an apparatus disposed above the tissue, where the apparatus includes at least two conductive structures, each having a non-linear configuration, where the at least two conductive structures are disposed substantially parallel to each other. In another example, the electrical property of the tissue is performed using an apparatus disposed above the tissue, where the apparatus includes at least one inductor structure.

An imaging device includes a camera 31, a light source 32, a polarizer 35 arranged between the camera 31 plus the light source 32 and an object 11, and a spatial light modulator 40A arranged between the polarizer 35 and the object 11 to control a revolution angle of an emitting light polarization plane relative to an incident light polarization plane.

Devices, systems, kits and methods for increasing the skin's permeability controlled by measured skin electrical parameter are described herein. They may be used for transdermal drug delivery and/or analyte extraction or measurement. The controlled abrasion device contains (i) a hand piece, (ii) an abrasive tip, (iii) a feedback control mechanism, (iv) two or more electrodes, and (v) an electrical motor. The feedback control mechanism may be an internal feedback control mechanism or an external feedback control. The kit contains the controlled abrasion-device, one or more abrasive tips, optionally with a wetting fluid. The method for increasing the skin's permeability requires applying the controlled abrasion device to a portion of the skin's surface for a short period of time, until the desired level of permeability is reached. Then the abrasion device is removed, and a drug delivery composition or device or an analyte sensor is applied to the treated site.

A non-invasive imaging device includes an illumination source comprising an incident light source to direct unpolarized light upon skin of a person, the incident unpolarized light having polarization properties including electrical and magnetic properties. The device also includes a detector for detecting light reflected from the skin, the light reflected from the skin of the person having polarization properties including electrical and magnetic properties. A host system coupled to the detector detects differences in polarization properties of the detected light reflected from the skin of the person compared to polarization properties of reflected light from the person at a different point in time and generates an assessment of skin health changes based on the differences.

The present invention relates to a process without a therapeutic target that evaluates at least one facial clinical sign and/or evaluates make-up, in particular evaluates wrinkles or fme lines from a portion of the face, including steps consisting in:from a sequence of facial images of a person filmed while emitting at least one sound, extract from the sequence one or more images coinciding with the emission of at least one predefined sound,from the resulting image or images extracted, evaluate at least one facial clinical sign appearing on the image or images extracted and/or evaluate at least one characteristic related to make-up.

A system for remote assessment of a patient, comprising: a first device associated to a physician, a second device associated to the patient, a medical device associated to the patient, wherein the second device is configured to communicate with the medical device, and wherein the medical device is configured to be programmed via the second device, wherein the first device is further configured to communicate with the second device, and wherein the second device is configured to be controlled via the first device, and wherein the second device is configured to acquire data indicative of at least one physiological parameter or of several physiological parameters of the patient. Furthermore, a method for remote assessment is provided.