Methods and apparatus for detection of tissue damage in patients using a medical device for an extended period of time are disclosed.

There is provided a system (100) and method for determining a water or lipid level of skin. The system (100) comprises at least two electrodes (108) suitable for contacting skin, and a signal generator (106) configured to generate an electrical signal at a frequency across the at least two electrodes (108). The system (100) is configured to measure a conductivity between the at least two electrodes (108). The system (100) is further configured to determine a water or lipid level of skin based on the measured conductivity and the frequency of the electrical signal.

There is provided a system (100) and method for determining a water or lipid level of skin. The system (100) comprises at least two electrodes (108) suitable for contacting skin, and a signal generator (106) configured to generate an electrical signal at a frequency across the at least two electrodes (108). The system (100) is configured to measure a permittivity between the at least two electrodes (108). The system (100) is further configured to determine a water or lipid level of skin based on the measured permittivity and the frequency of the electrical signal.

An apparatus includes a body and an actuator is coupled to the body. A needle is mounted to the actuator. The needle comprises a slot along a length to a tip. A sensor is coupled to a plurality of wires. A base is configured to be moveable by the actuator and includes a cutout, a circuit board having a microprocessor, and a plurality of contacts. Each contact is coupled to a wire of the plurality of wires. A power source is connected to the circuit board and to the base. A bracket is coupled to the bottom surface of the body and configured to receive the base. A patch is coupled to the bracket and has an adhesive. A needle is configured to be moveable by the actuator. The plurality of wires extend from the circuit board of the base, through the needle and out of the slot.

Multi-modal, portable, handheld devices for tissue assessment (e.g., wound assessment) are provided, as are methods of fabricating and methods of using the same. The devices can be used for virtual medicine (VM)-based wound management, such as VM-based diabetic foot triage (DFT) and management. The device can be used to take physiological measurements of temperature and/or tissue oxygenation of a wound to assess the wound, for example in a remote setting environment. The device can also be used to provide therapy for tissue repair and/or wound healing, apart from the multi-modal imaging of the tissue surface of the patient. For example, light therapy, such as low-level light therapy (LLLT) can be provided via one or more light emitting diodes (LEDs) and/or laser diodes.

A method, system, apparatus, and/or device that may include: a first sensor operable to take a first physiological measurement; a second sensor operable to take a second physiological measurement; and a processing device operatively coupled to the first sensor and the second sensor. The processing device may be operable to: receive a first measurement data for the first physiological measurement; receive a second measurement data for the second physiological measurement; generate an event data set based on the first measurement data with the second measurement data; determine an event occurred based on the event data set; determine a type of the event; and in response to the event being a safety event: determine a type of the safety event; identify a risk level of the safety event; and in response to the risk level exceeding a threshold level, notify a second device of the safety event.

Methods and apparatus for detection of tissue damage in patients using a medical device for an extended period of time are disclosed.

In some embodiments, a computer-implemented method of generating a visualization of wavelength-dependent surface characteristics is provided. A computing device receives an input image captured by a camera, wherein the input image includes information in a low-dimensional color space. The computing device processes the input image to determine spectrum band information in a high-dimensional color space that corresponds to the input image. The computing device extracts subtractive information from the spectrum band information to obtain wavelength-dependent surface characteristic information, The computing device generates the visualization using the wavelength-dependent surface characteristic information. In some embodiments, the computing device may be a smartphone.

Instruments and methods for wide-field polarized imaging of the skin to determine an outer lesion margin objectively in vivo to provide guidance to a surgeon. Quantitative characterization of collagen structures in the skin can be used to determine the outer lesion margin or monitor skin treatment.

An automatic tattoo apparatus can be used to robotically apply tattoos. A customer can shop on an online tattoo marketplace to select designs created by various artists located anywhere. The online tattoo marketplace can process and manage payments, artist and/or customer profiles, bookings, tattoo design uploads, browsing and design selection, design changes, and/or perform other actions. The automatic tattoo device can apply tattoos precisely, quickly, and may with reduced pain. The tattoo apparatus can apply a wide range of different types of tattoos, including but not limited to micro tattoos, dotwork, blackwork tattoos, realism tattoos, fine-line tattoos, etc.