Disclosed are instruments and methods for acquiring co-registered orthogonal fluorescence and photoacoustic volumetric projections of an interrogated object. In an embodiment, an instrument includes a rotary mechanism configured to rotate an interrogated object relative to an array of photoacoustic transducers and an optical detector. An optical excitation unit is configured to irradiate the interrogated object with pulses of light, inducing both fluorescence and photoacoustic responses inside the interrogated object at each of a plurality of rotational positions. The array of photoacoustic transducers includes unfocused elements arranged in a pattern along an axis of rotation, the elements configured to detect photoacoustic signals generated inside the volume of the interrogated object. The optical detector is arranged opposite to the array of photoacoustic transducers with respect to the axis of rotation and is configured to register sources of fluorescence excited inside the interrogated object. Each of the optical excitation axes form with each of the optical detection axes, and with each of the photoacoustic detection axes, angles that are between 60° and 90° so as to enable acquisition of co-registered orthogonal fluorescence and photoacoustic volumetric projections of the interrogated object.

An optical system for the detection of skin disease, such as melanoma, acquires images of a lesion on a subject's skin at different wavelengths and utilizes a sweeping arm rotating about the lesion in a clock-like sweep to produce diagnostically relevant metrics and classifiers from the image data so as to enhance detection of the skin disease.

The present disclosure provides methods of providing a continuity of care for a patient during transfer between care settings. The method includes the steps of deciding to transfer a patient from a first care setting to a second care setting, performing a first assessment of the patient in the first care setting, preparing a transfer record of the assessment, and transferring the transfer record with the patient to the second care setting.

A surface of the tissue is illuminated with light having a known wavelength spectrum capable of materially penetrating the tissue. The light remitted from the tissue in response to the illumination is separated into at least two distinguishable polarization components. The intensity of the illumination light remitted from the tissue is measured over a hyperspectral range of wavelengths for the at least two distinguishable polarization components. Based on the preceding measurements and a degree of linear polarization of the remitted light, data representative of the three-dimensional location and one or more characteristics of an abnormal portion of the tissue are produced. Further, the masking effect of melanin may be eliminated to obtain accurate estimations of an anomaly.

The invention relates to a method for recommending cosmetics, skin care products and/or dermatological products that are adapted to the condition of the skin.

An electronic device may include a housing and a PhotoPlethysmoGram (PPG) sensor disposed inside the housing. The PPG sensor may include a first Light Emitting Diode (LED) configured to generate light in a first wavelength band, a second LED configured to generate light in a second wavelength band, a third LED configured to generate light in a third wavelength band, a fourth LED configured to generate light in a fourth wavelength band, and a light receiving module including at least one photo diode. The electronic device may include a processor operatively coupled with the PPG sensor and a memory operatively coupled with the processor. The memory may include instructions that, when executed, cause the processor to measure optical densities of the light generated by the first LED to the fourth LED, and calculate a blood glucose value based at least in part on the measured optical densities.

A system includes a focus optic configured to converge an electromagnetic radiation (EMR) beam to a focal region located along an optical axis. The system also includes a detector configured to detect a signal radiation emanating from a predetermined location along the optical axis. The system additionally includes a controller configured to adjust a parameter of the EMR beam based in part on the signal radiation detected by the detector. The system also includes a window located a predetermined depth away from the focal region, between the focal region and the focus optic along the optical axis, wherein the window is configured to make contact with a surface of a tissue.

The present disclosure provides systems and methods for calibrating for errors dependent upon spectral characteristics of tissue for a medical device by estimating a spectral characteristic of tissue providing error due to scattering or absorption of emitted light based upon operating the sensor in reflectance mode to generate a first SpO.sub.2 reading and estimating error due to spectral characteristics of skin therefrom, operating the sensor in transmissive mode to generate a second SpO2 reading, and applying a correction to a pulse oximetry transmissive mode measurement to correct for the error dependent upon the estimated spectral characteristic of tissue.

Provided herein is a system for measuring and analyzing skin and hair, which includes a skin and hair measurement and analysis device, a smart terminal of a user in which an application interlinked with the skin and hair measurement and analysis device is installed, and a server interlinked with the skin and hair measurement and analysis device and interlinked with the smart terminal.

An electronic device may include: an optical sensor configured to emit a reference light to a reference object and detect the reference light reflected from the reference object during calibration, and emit a measurement light to a target object and detect the measurement light reflected from the target object during a measurement; a display; and a processor configured to: when the electronic device is placed on a charger and is in a charging state, perform the calibration of the optical sensor based on the reference light reflected from the reference object; control the display to output guide information for estimating bio-information according to progress stages of the measurement after charging of the electronic device; and estimate the bio-information based on a light quantity of the measurement light that is reflected from the target object, and a light quantity of the reference light reflected from the reference object.