A method and apparatus for tracking disease progression as revealed by multiple lesions perform a global optimization to identify corresponding lesions by overlap, for example, after outlines of the lesions have been morphologically dilated. A clustering algorithm addresses the problem of lesions separating into parts or joining together to provide a clear picture of disease progression.

Various methods and systems for designing a restored smile are provided. One method includes receiving scan data of a patient's teeth, developing a digital model of the patient's teeth via a computing device, where the model represents the patient's teeth based upon the scan data, creating a dental treatment plan to restore one or more teeth from an initial condition to a successive condition, and wherein a final condition of the one or more is based on the one or more teeth having at least one planned additional restorative tooth structure provided therewith.

A method for determining a disease state prediction, relating to a potential disease or medical condition of a subject, includes accessing a set of subject images, the subject images capturing a part of a subject's body, and accessing a set of clinical factors from the subject. The clinical factors are collected by a device or a medical practitioner substantially contemporaneously with the capture of the subject images. The subject images are inputted into an image model to generate disease metrics for disease prediction for the subject. The disease metrics generated by the image model and the clinical factors are inputted into a classifier to determine the disease state prediction, and the disease state prediction is returned.

A method of determining a cosmetic skin attribute of a person is provided. The method includes obtaining a color channel image of a person's skin, analyzing the color channel image with a computer using entropy statistics to obtain an entropy value, and then determining a cosmetic skin attribute for the person based on the entropy value.

Methods and apparatus for detection of tissue damage in users using a PPE device for an extended period of time are disclosed.

Device comprising polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising: hydrophilic monomer; and indicator monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer; characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10
and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.

Scalable, configurable, complete spectrum universal health metrics monitors and bicorders are disclosed that record data or make selected determinations from a complete spectrum of health determinations regarding or utilizing sensor observations of people. Universal health metrics monitors utilize necessary resources and predetermined criteria in their making of selected health determinations. Universal health metrics monitors may utilize measure points in their locating of selected analytically rich aspects, characteristics, or features of or from sensor observation-derived representations, Universal health metrics monitors assign appropriate informational representations to selected analytically rich aspects, characteristics, features, or measure points, which are stored in datasets where they can be utilized in real-time or thereafter by universal health metrics monitors in their making of selected health determinations regarding or utilizing sensor observations or people who are subjects of sensor observations.

A system and method for monitoring and auditing the patient's health care compliances in order to detect bedside patient's information such as bed sores, oral health care, insertion of invasive devices, patient positions etc. The system employs visual sensors such as lidars, IR cameras etc. for observing the patients. The system also uses machine learning algorithms that use the bedside patient information into pre-trained models so as to monitor, trace and diagnose patient histories by the caretakers.

A skin cleanser includes a surface, such as a silicone surface, with at least one textured portion for transmitting vibrational tapping to the skin. The skin cleanser includes at least one oscillating motor for generating the tapping motion to the skin. The textured portion in touch-points or a wave that transmit the tapping motion to skin in contact with the to portions. The touch-points may include thicker and thinner formations of the touch-points to provide firmer or softer vibrations to the skin. The touch-points are within about 0.5 to 2.5 mm in diameter. One configuration includes multiple oscillating motors configured to provide different vibration frequencies at around 50-300 Hertz and operable simultaneously.

A skin cleanser includes a surface, such as a silicone surface, with at least one textured portion for transmitting vibrational tapping to the skin. The skin cleanser includes at least one oscillating motor for generating the tapping motion to the skin. The textured portion includes touch-points or a wave that transmit the tapping motion to skin in contact with the textured portions. The touch-points may include thicker and thinner formations of the touch-points to provide firmer or softer vibrations to the skin. The touch-points are within about 0.5 to 2.5 mm in diameter. One configuration includes multiple oscillating motors configured to provide different vibration frequencies at around 50-300 Hertz and operable simultaneously.