In one embodiment, the present disclosure is directed to a method for providing a neural stimulation therapy to treat chronic pain of a patient. The method comprises: recording, using a neural sensing system, neural activity of the patient at one or more sites within the nervous system of the patient related to the chronic pain of the patient, modifying a computational neural modeling system to model the sensed neural activity of the patient; computing a respective neural response of the patient for each of a plurality of different temporal stimulation patterns using the modified computational neural modeling system; selecting, based on the respective neural responses, one of the plurality of temporal stimulation patterns; and programming an implantable stimulation system to provide the selected one of the plurality of temporal stimulation patterns to the patient to treat the chronic pain of the patient.

Systems and methods are disclosed in which changes in the position and/or orientation of an anatomical structure or of a surgical tool can be measured quantitatively during surgery. In some embodiments, the systems and methods disclosed herein can make use of inertial motion sensors to determine a position or orientation of an instrument or anatomy at different times and to calculate changes between different positions or orientations. In other embodiments, such sensors can be utilized in conjunction with imaging devices to correlate sensor position with anatomical landmarks, thereby permitting determination of absolute angular orientation of a landmark. Such systems and methods can facilitate real-time tracking of progress during a variety of procedures, including, e.g., spinal deformity correction, etc.

Systems and methods are disclosed in which changes in the position and/or orientation of an anatomical structure or of a surgical tool can be measured quantitatively during surgery. In some embodiments, the systems and methods disclosed herein can make use of inertial motion sensors to determine a position or orientation of an instrument or anatomy at different times and to calculate changes between different positions or orientations. In other embodiments, such sensors can be utilized in conjunction with imaging devices to correlate sensor position with anatomical landmarks, thereby permitting determination of absolute angular orientation of a landmark. Such systems and methods can facilitate real-time tracking of progress during a variety of procedures, including, e.g., spinal deformity correction, etc.

A load sensing assembly for a spinal implant includes a set screw having a central opening that extends from a first end of the set screw toward a second end of the set screw. The second end of the set screw is configured to engage with an anchoring member. The load sensing assembly includes an antenna, an integrated circuit in communication with the antenna, where the integrated circuit is positioned within the central opening of the set screw, and a strain gauge in connection with the integrated circuit. The strain gauge is located within the central opening of the set screw in proximity to the second end of the set screw.

The present disclosure provides a system and method for image data acquisition. The method may include obtaining image data of a subject including a first type of tissue and a second type of tissue. The method may include determining, based on the image data of the subject, a target portion including at least a portion of at least one of the first type of tissue or the second type of tissue. The method may include determining, based at least in part on the target portion represented in the image data, a scan mode corresponding to the target portion. The method may include causing an imaging device to acquire, based on the scan mode, image data of the target portion.

Systems and methods for estimating anatomic alignment between two or more bones are described herein. An example method can include registering an anatomic reference frame. Additionally, the method can include establishing a respective rotational relationship between each of one or more bones and an orientation sensor attached to each of the one or more bones. The method can also include receiving, from each of the orientation sensors, orientation information, and then calculating an orientation of a bone relative to the anatomic reference frame. The method can further include calculating, using the respective orientations of the bones relative to the anatomic reference frame, an anatomic alignment parameter between first and second bones.

A single-sided magnet and magnetic resonance imaging (“MRI”) system are portable and lightweight, enabling use as a point-of care (“POC”) MRI device. The portable MRI system includes a magnet assembly containing layers of magnet blocks, such as rare-earth magnet blocks. The magnet blocks are arranged in concentric rings in each layer, and surround a central aperture extending through the magnet assembly. The central aperture is sized to allow a medical instrument, such as a needle, to pass through the central aperture. The portable MRI system can therefore be used for image guidance in lumbar puncture (“LP”) and other medical procedures.

Minimally-invasive spinal inventions are often performed using fluoroscopic imaging methods, which can give a real-time impression of the location of a surgical instrument, at the expense of a small field of view. When operating on a spinal column, a small field of view can be a problem, because a medical professional is left with no reference vertebra in the fluoroscopy image, from which to identify a vertebra, which is the subject of the intervention. Identifying contiguous vertebrae is difficult because such contiguous vertebrae are similar in shape. However, characteristic features, which differentiate one vertebra from other vertebra, and which are visible in the fluoroscopic view, may be used to provide a reference.

Disclosed are biodegradable glass substrates that are useful as functional elements of solid-state devices. In particular, biodegradable glass substrates having a rapidly degradable glass and a slowly degradable glass provide a structural platform that completely dissolves following a desired operational lifetime of devices such as implanted electronic devices, implanted sensor devices, and optical fibers.

A load balance and alignment system is provided to assess load forces on the vertebra in conjunction with overall spinal alignment. The system includes a spine instrument having an electronic assembly and a sensorized head. The sensorized head can be inserted between vertebra and report vertebral conditions such as force, pressure, orientation and edge loading. A GUI is therewith provided to show where the spine instrument is positioned relative to vertebral bodies as the instrument is placed in the inter-vertebral space. The system can report optimal prosthetic size and placement in view of the sensed load and location parameters including optional orientation, rotation and insertion angle along a determined insert trajectory.