An apparatus comprising at least one sensor to detect the position and/or orientation of a body portion of a subject, the sensor in communication with a computing device to process sensor data and optionally a transmitter to transmit sensor data between the sensor and the computing device and/or one or more computing devices.

A method is disclosed for spinal anatomy segmentation. In one example, the method includes combining a fully convolutional network with a residual neural network. The method also includes training the combined fully convolutional network with the residual neural network from end to end. The method also includes receiving at least one medical image of a spinal anatomy. The method also includes applying the fully convolutional network with the residual neural network to at least one medical image and segmenting at least one vertebral body from the at least one medical image of the spinal anatomy.

Neurophysiological instruments and techniques are improved through various enhancements. Stimulation of an instrument is possible while it is advancing into the spine or elsewhere, alerting the surgeon to the first sign the instrument or device (screw) may be too near a nerve. A directional probe helps surgeons determine the location of the hole in the pedicle. Electrically insulating sleeves prevent shunting into the soft tissues. According to a different improvement, the same probe to be used to stimulate different devices, such as screws and wires. Electrical impulses may be recorded from non-muscle regions of the body, including the spine and other portions of the central nervous system as opposed to just the extremities.

A method of assessing spinal column stability involves receiving image data corresponding to a spinal column of a patient; determining, based on the image data, a material strength of bony anatomy in at least a portion of the spinal column; completing a first stability assessment of the spinal column, based at least in part on the determined material strength; modifying the image data to simulate removal of bony anatomy or soft tissue from the spinal column to yield modified image data; and completing a second stability assessment of the spinal column, based at least in part on the determined material strength and the modified image data.

Implementations described herein include surgical distraction devices having a distal movement assembly having a pusher plate comprising a first slot extending along a first axis disposed in a first side and a second slot extending along a second axis disposed in a second side thereof. The first axis is oriented at an angle of from about 60 to about 160 degrees from the second axis. The device further includes a first and second paddles, each paddle having a corresponding engagement mechanism for movably coupling the respective first or second paddle to the pusher plate when engaged in the respective slot. Rotational actuation of the proximal drive assembly causes proximal or distal movement of the pusher plate, causing the first and second engagement members to move relative to their respective slots, thereby moving the first paddle and the second paddle in opposing directions. Methods of using such surgical distraction devices to determine size of an intervertebral space are also described.

It is disclosed an apparatus for restoring voluntary control of locomotion in a subject suffering from a neuromotor impairment comprising a multidirectional trunk support system and a device for epidural electrical stimulation. The robotic interface is capable of evaluating, enabling and training motor pattern generation and balance across a variety of natural walking behaviors in subjects with neuromotor impairments. Optionally, pharmacological cocktails can be administered to enhance rehabilitation results. It is also disclosed a method for the evaluation, enablement and training of a subject suffering from neuromotor impairments by combining robotically assisted evaluation tools with sophisticated neurobiomechanical and statistical analyses. A method for the rehabilitation (by this term also comprising restoring voluntary control of locomotion) of a subject suffering from a neuromotor impairment in particular partial or total paralysis of limbs, is also disclosed.

Diagnostic systems and methods for measuring and assessing spine instability are described which involve reconstruction of a dynamic three-dimensional model of a patient's spine moving through a range of motions, and optimization of the three-dimensional model to provide relative three-dimensional position and orientation data for each vertebra in the spine throughout the motion. Vertebral movement is thereby accurately measured and instability determined for presentation in a user-friendly form.

A method of a measuring kinematic parameter in a subject is provided. The method includes obtaining a first magnetic resonance (MR) image set of a bone marrow segment of the subject in a first position and obtaining a second MR image set of the bone marrow segment of the subject in a second position where the second position different from the first position. The method further includes registering the first image set with the second image set and measuring a kinematic parameter.

Systems and methods for monitoring a range of motion of a joint are described. For example, in one embodiment, a first set of sensors may sense accelerations of a first body portion located on a first side of the joint and a second set of sensors may sense accelerations of the second body portion located on a second opposing side of the joint. The acceleration data may then be used to compute the relative motion of the first and second body portions to determine movement of the joint. This joint movement may then be used to determine one or more range of motion movement metrics which are output for viewing by a subject or medical practitioner.

Systems and methods are disclosed in which changes in the position and/or orientation of an anatomical structure or of a surgical tool can be measured quantitatively during surgery. In some embodiments, the systems and methods disclosed herein can make use of inertial motion sensors to determine a position or orientation of an instrument or anatomy at different times and to calculate changes between different positions or orientations. In other embodiments, such sensors can be utilized in conjunction with imaging devices to correlate sensor position with anatomical landmarks, thereby permitting determination of absolute angular orientation of a landmark. Such systems and methods can facilitate real-time tracking of progress during a variety of procedures, including, e.g., spinal deformity correction, etc.