A method of calculating in vivo force on an anterior cruciate ligament (ACL) by measuring one or more biomechanical properties during a biomechanical screening task to obtain one or more biomechanical datum from the measured one or more biomechanical properties, and calculating a total load on an anterior cruciate ligament from an ACL force model using the one or more biomechanical datum as inputs to the ACL force model. The ACL force model is defined by F.sub.ACL=F.sub.ACL.sup.sag+F.sub.ACL.sup.front+F.sub.ACL.sup.trans+Σ.sub.jCT.sub.j, wherein F.sub.ACL is the total force on the ACL, F.sub.ACL.sup.sag is the force on the ACL in a sagittal plane, F.sub.ACL.sup.front is the force on the ACL in the frontal plane, F.sub.ACL.sup.trans is the force on the ACL in the transverse plane, and CT.sub.j is the ACL force interaction relationships among the sagittal-frontal (SF), sagittal-transverse (ST), and frontal-transverse (FT) planes, where j=SF, ST, FT.

The invention relates to apparatus to be worn at or adjacent to the knee joint of a person to detect the impact effect of forces applied to the knee joint and, as a result of the detection, and typically analysis of information relating to the person wearing the apparatus, feedback information is provided to the person, in one embodiment during the time when the apparatus is being worn, so as to provide timely feedback to the person wearing the apparatus of the impact on the PF joint. The person wearing the apparatus or monitoring the same can use the feedback whilst the apparatus is being worn, in order to allow the person to change their movement or stop their movement with immediate effect and thereby prevent or minimise the risk of the injury occurring.

An apparatus comprising at least one sensor to detect the position and/or orientation of a body portion of a subject, the sensor in communication with a computing device to process sensor data and optionally a transmitter to transmit sensor data between the sensor and the computing device and/or one or more computing devices.

A method is provided for monitoring and managing muscle activity and soft tissue loading. The method includes providing to a subject a plurality of sensors for measuring muscle activity and soft tissue loading levels; directing the subject to undertake a program of exercise; measuring muscle activity and soft tissue loading during the program of exercise; comparing the measured muscle activity and soft tissue loading levels against calibrated muscle activity and soft tissue loading levels for the subject; and alerting the subject if the comparison of measured muscle activity and soft tissue loading levels against calibrated muscle activity and soft tissue loading levels indicates that a desirable level of muscle activity and/or soft tissue loading is being exceeded.

A method and system for measuring tension, pressure, and distance of knee tissue, the system comprising a prosthetic inlay device comprising at least two platform structures, wherein each of the platforms are supported on a scissor arm structure and a coil spring, a force sensing sensor configured beneath each coil spring, and a connector cable coupled to the force sensing sensors.

A knee brace is provided for monitoring the knee. The knee brace includes a dock for removably receiving a control module. The control module is electrically coupled with the dock when the control module is received in the dock. The knee brace includes a sensor for measuring a physiological state of the wearer. The sensor is electrically coupled to the control module by way of the first conductive path when the control module is received in the dock.

A method of treating osteoarthritis by modifying the shape change of bone(s) underlying articular cartilage, comprising evaluating the bone shape of the patient's joint, injecting the patient with a peptide of SEQ ID No. 1 or applying other therapeutic interventions that can reduce the shape change of the bone(s) underlying articular cartilage, and thereafter evaluating the bone shape of the patient's joint is disclosed.

A method of a measuring kinematic parameter in a subject is provided. The method includes obtaining a first magnetic resonance (MR) image set of a bone marrow segment of the subject in a first position and obtaining a second MR image set of the bone marrow segment of the subject in a second position where the second position different from the first position. The method further includes registering the first image set with the second image set and measuring a kinematic parameter.

A gait analysis system includes a foot sensing unit, a knee sensing unit and a portable device. The foot sensing unit senses pressure information. The knee sensing unit senses first and second three-dimensional rotational attributes of knee. The portable device generates direction of ground reaction force according to the pressure information, the first and the second three-dimensional rotational attributes of knee and a model of direction of ground reaction force, generates knee moment according to the pressure information, the first and the second three-dimensional rotational attribute of knee, the direction of ground reaction force, length of tibia and model of knee moment, determines gait information according to a gait model and one of the pressure information, the first and the second three-dimensional rotational attributes of knee, and generates gait analysis result according to the gait information, the knee moment and the gait model.

Systems and methods for monitoring a range of motion of a joint are described. For example, in one embodiment, a first set of sensors may sense accelerations of a first body portion located on a first side of the joint and a second set of sensors may sense accelerations of the second body portion located on a second opposing side of the joint. The acceleration data may then be used to compute the relative motion of the first and second body portions to determine movement of the joint. This joint movement may then be used to determine one or more range of motion movement metrics which are output for viewing by a subject or medical practitioner.