Embodiments of the invention are broadly drawn to methods for determining an optimum dose of an antiarrhythmic drug, for example sotalol. In particular, the method involves titrating the dose of the drug gradually to determine the optimum plasma concentration for a patient, whether the patient has normal or abnormal renal function.

Nano-node sunscreen described herein enables significantly improved health monitoring and treatment of sun-related issues by utilizing internal (in-body) mechanisms and information and external mechanisms and information.

A physical area network for detecting head injuries described herein enables significantly improved cranial health monitoring and treatment by utilizing internal (in-body) mechanisms and information and external mechanisms and information.

For patient weight estimation in a medical imaging system, a patient model, such as a mesh, is fit to a depth image. One or more feature values are extracted from the fit patient model, reducing the noise and clutter in the values. The weight estimation is regressed from the extracted features.

The invention relates to an apparatus (2, 3), comprising a mating unit (20-1, 20-2) for releasably attaching the apparatus (2) to a medical device (1) or for releasably receiving at least a part of the medical device (1). The apparatus (2, 3) further comprises one or more optical sensors (25, 26) and/or one or more acoustical sensors (27) for determining information related to a condition and/or use of the medical device (1). The invention further relates to a system comprising such an apparatus (2, 3) and such a medical device (1), to a method (500, 600, 700) and a computer program (61) for determining information related to a condition and/or use of such a medical device (1), and to a computer-readable medium (60) storing such a computer program (61).

The present disclosure describes methods and systems for predicting severe disease in an individual with sepsis or at risk of developing sepsis, in order to prevent severe disease in an individual with sepsis. The present disclosure also describes methods of using topological data analysis and/or clustering to stratify sepsis based on biomolecular signatures and identify distinct phenotypes in sepsis patients.

A biological function estimation device includes a processor configured to predict a drug reaction in a patient based on an evaluation value obtained by evaluating a biological function of the patient from a test result before drug administration and data on a drug to be administered to the patient, and configured to correct the evaluation value according to a comparison result between an obtained prediction value and a measurement value obtained by measuring the drug reaction after the drug administration.

A drug overdose detection apparatus that is configured to measure the blood oxygen level of a user and upon detection in a drop thereof provide administration of a substance to counteract the drug overdose. The present invention includes a housing that is configured to be worn by a user has an interior volume. Disposed in the interior volume of the housing is a substance administration assembly wherein the substance administration assembly includes a syringe member, a plunger member and a plunger driver. A motor is operably coupled to the plunger driver and facilitates movement thereof. A spring needle assembly is operably coupled to the substance administration assembly and includes a spring biased needle that is operable to inject into a patient so as to inject the substance. The present invention further includes an audio alarm and transceiver configured to provide alerts and transmit signals.

Techniques related to temporary setpoint values are disclosed. The techniques may involve causing operation of a fluid delivery device in a closed-loop mode for automatically delivering fluid based on a difference between a first setpoint value and an analyte concentration value during operation of the fluid delivery device in the closed-loop mode. Additionally, the techniques may involve obtaining a second setpoint value. The second setpoint value may be a temporary setpoint value to be used for a period of time to regulate fluid delivery, and the second setpoint value may be greater than the first setpoint value. The techniques may further involve causing operation of the fluid delivery device for automatically reducing fluid delivery for the period of time based on the second setpoint value.

Method, device and system for providing consistent and reliable glucose response information to physiological changes and/or activities is provided to improve glycemic control and health management.