Disclosed herein is a multi-electrode catheter system including an amplifier stage and an amplifier interface. The amplifier stage includes at least a first quantity of amplifier channels. The amplifier interface includes a first interface having at least the first quantity of interface channels. The amplifier channels are respectively electrically coupled to the interface channels The amplifier interface includes a second interface having a second quantity of catheter channels, the second quantity being greater than the first quantity. The catheter channels are configured to be respectively electrically coupled to corresponding electrode leads of a multi-electrode catheter. The amplifier interface includes a switching matrix electrically coupled between the first interface and the second interface. The switching matrix is configured to selectively electrically couple a selected subset of catheter channels to respective interface channels of the first quantity of interface channels.

A microelectromechanical device and method for neuroprosthetics comprises microactuators and microelectrodes. The microelectrodes are to be positioned in a nerve bundle and bonded with the microactuators through an interconnect. The position of each of the microactuators can be individually tuned through control signals so that the microelectrodes are implanted at desired positions in the nerve bundle. The control signals are transmitted to the microactuators and generated with a open-loop or closed-loop control scheme that uses signals acquired by the microelectrodes from the nerve bundle as feedback.

There is provided a control device including: a determination unit configured to determine a mounted state of a detection device on the basis of a plurality of detection values, the detection unit including a light source and a plurality of light receiving elements and detecting a pulse wave, the plurality of detection values corresponding to signals output in response to light beams received from the plurality of light receiving elements, respectively, distances between the light source and the respective plurality of light receiving elements being different from each other; and an operation control unit configured to control an operation related to detection of the pulse wave performed by the detection device on the basis of a determination result of the mounted state.

Drug delivery member insertion depth sensing assemblies, drug delivery devices, and methods for determining an insertion depth of a drug delivery member are disclosed. The sensing assemblies can include electrical sensing assemblies with direct or indirect measurement components or optical sensing assemblies with one or more light sources and one or more photodiodes. A controller of the sensing assemblies can receive data associated with the drug delivery member in an insertion position. The data can then be correlated to an insertion depth of the drug delivery member.

An optical sensor can be multiplexed for different clients/features including estimating information or characteristics of a user's physiological signals. Additionally, the clients/features can include estimating information or characteristics independent from a user's physiological signals. As the number of clients increase and/or as the requirements for the clients increase, flexibility can be provided to accommodate the various clients. Parallelization of the optical sensor can be used to improve performance as the number of clients increase. For example, the hardware and software architecture can assemble patterns of time slots that measure all desired light paths for the multiple clients and distribute the corresponding measurements to each client according to the client requests. In some examples, the scanning sequence can be represented by frames including slots associated with multiple clients to compress the representation for larger or more complex scan sequences.

A cannula with a proximally mounted camera provides visualization of the brain during minimally invasive surgery. The device comprises a cannula with a camera mounted on the proximal end of the cannula with a view into the cannula lumen and the surgical field below the lumen. A prism, reflector or other suitable optical element is oriented between the camera and the lumen of the cannula to afford the camera a view into the cannula while minimizing obstruction of the lumen.

A surgical instrument includes an end effector having a first jaw, a second jaw movable relative to the first jaw to grasp tissue therebetween, an anvil, a staple cartridge comprising staples deployable into the tissue, wherein the staples are deformable by the anvil, and a sensor configured to provide a sensor signal according to a physiological parameter of the tissue. The surgical instrument further includes a control circuit coupled to the sensor, wherein the control circuit is configured to receive the sensor signal, and assess proximity of the sensor to cancerous tissue based on the sensor signal.

A surgical access assembly comprises a trocar and a surgical instrument. The trocar comprises a housing and an access tube extending distally from the housing. The housing comprises a hollow light emitter. The housing and the access tube define a lumen extending through the housing and the access tube. The hollow light emitter is configured to project light in the lumen. The surgical instrument comprises an end effector and a shaft extending proximally from the end effector. The shaft comprises an optical receiver positioned within reach of the light from the hollow light emitter. The shaft further comprises a light guide extending from the optical receiver along at least a portion of the shaft toward the end effector.

A tissue penetrating system has a housing member, a plurality of penetrating members positioned in the housing member and a plurality of sample chambers. Each sample chamber is associated with a penetrating member. A tissue stabilizing member has a tissue interface surface configured to be applied to a tissue surface and provide for spontaneous flow of blood for sample capture. The tissue stabilizing member is coupled to the housing.

A pair of new catheters designed to be deployed as a catheter system to allow a simultaneous acquisition of electrograms from widely dispersed electrodes in the left atrium, right atrium, and coronary sinus. The first catheter is the spiral globe catheter which has the primary shape of a spiral globe and has additional modifications to facilitate safe entry into the left atrium, to orient the primary axis of the spiral globe toward the mitral valve, and to maximize contact of electrodes to multiple areas of the left atrium. The second catheter is the right atrial and coronary sinus catheter (RA-CS catheter) which allows for electrogram acquisition from the length of the coronary sinus and dispersed areas of the right atrium. The catheter system is designed to provide adequate electrode sensor information so that panoramic mapping of the both atria and the coronary sinus may be performed.