A system includes signal acquisition circuitry and a processing unit. The signal acquisition circuitry is configured to receive multiple intra-cardiac signals acquired by multiple electrodes of an intra-cardiac probe in a heart of a patient. The processing unit is configured to select a group of the intra-cardiac signals, extract a respective most-likely annotation value from each of the intra-cardiac signals in the group, in accordance with a likelihood criterion, identify in the group an intra-cardiac signal whose most-likely annotation value is statistically deviant in the group by more than a predefined measure of deviation, extract, from the intra-cardiac signal having the statistically deviant annotation value, at least a second-most-likely annotation value in accordance with the likelihood criterion, and, responsive to a statistical deviation of the second-most-likely annotation value, select a valid annotation value for the corresponding intra-cardiac signal.

A biological information measuring device comprises: a plurality of sensors that each acquire a base signal containing biological information and noise information; and a processing device that acquires biological information on the basis of a plurality of base signals. The processing device comprises: a component analysis part that performs a prescribed component analysis on the basis of the plurality of base signals and generates a plurality of component signals which constitute the plurality of base signals; and a biological information acquisition part that determines whether a component signal is biological information.

An electronic system for non-invasive monitoring of estrogen of a female human comprises a wearable device and a processor. The wearable device includes a first sensor system configured to be worn in contact with the skin of the female human and to determine a level of perfusion of the female human. The processor is configured to receive and store the level of perfusion of the female human from the first sensor system for a respective point in time. The processor is further configured to determine a change in the level of perfusion of the female human, using the levels of perfusion of the female human stored for a plurality of respective points in time. Furthermore, the processor is configured to detect a change in estrogen level of the female human based on the change in the level of perfusion of the female human.

A system and method for modeling and visualizing ST segment morphology in an ECG. Many cardiac conditions show ST-elevation in ECG data and may be misdiagnosed as a consequence. The exemplary embodiments model a segment in the ECG with a curve and extract features from the curve to discriminate between the cardiac conditions, including STEMI.

Medical devices and related patient management systems and parameter modeling methods are provided. An exemplary method of operating a sensing device associated with a patient involves obtaining current operational context information associated with the sensing device, obtaining a parameter model associated with the patient, calculating a current parameter value based on the parameter model and the current operational context information, obtaining one or more signals from a sensing element configured to measure a condition in a body of the patient, and providing an output that is influenced by the calculated current parameter value and the one or more signals.

Systems and methods for non-invasive blood pressure measurement are disclosed. In some embodiments, a system comprises a wearable member configured to generate first and second signals (e.g., PPG signals), and a blood pressure calculation system. The blood pressure calculation system includes a wave selection module configured to identify subsets of waves of the signals, a feature extraction module configured to generate sets of feature vectors form the subsets of waves, and a blood pressure processing module configured to calculate an arterial blood pressure value based on the sets of feature vectors and an empirical blood pressure calculation model, the empirical blood pressure calculation model configured to receive the sets of feature vectors as input values. The blood pressure calculation system further includes a communication module configured to provide a message including or being based on the arterial blood pressure value.

An electronic device receives a first input, where an air pump inflates and pressurizes an airbag. The electronic device obtains a pressure value of the airbag in a process of controlling the air pump to inflate and pressurize the airbag. The electronic device obtains a first pressure signal, where the first pressure signal is a signal indicating that the pressure value of the airbag changes with time in a process in which the air pump starts to inflate and pressurize the airbag until the pressure value of the airbag is equal to a preset pressure value. The electronic device determines, based on the first pressure signal, tightness of wearing a wristband by a user. The electronic device corrects, based on the tightness, a blood pressure measurement value determined based on a second pressure signal, to determine a blood pressure value of the user.

The invention provides a body-worn system that continuously measures pulse oximetry and blood pressure, along with motion, posture, and activity level, from an ambulatory patient. The system features an oximetry probe that comfortably clips to the base of the patient's thumb, thereby freeing up their fingers for conventional activities in a hospital, such as reading and eating. The probe secures to the thumb and measures time-dependent signals corresponding to LEDs operating near 660 and 905 nm. Analog versions of these signals pass through a low-profile cable to a wrist-worn transceiver that encloses a processing unit. Also within the wrist-worn transceiver is an accelerometer, a wireless system that sends information through a network to a remote receiver, e.g. a computer located in a central nursing station.

Some embodiments of a system or method for treating heart tissue can include a control system and catheter device operated in a manner to intermittently occlude a heart vessel for controlled periods of time that provide redistribution of blood flow. In particular embodiments, the system can be configured to provide an estimation of the cumulative effects of the treatment. For example, some embodiments of the system or method can treat myocardium that is at risk of infarction by intermittently altering blood flow in a venous system to induce microcirculation within the myocardium, and can output a cumulative dosage value indicative of a measurement of progress of reducing an infarct size.

A medical device is configured to sense a cardiac electrical signal and determine from the cardiac electrical signal at least one of a maximum peak amplitude of a positive slope of the cardiac electrical signal and a maximum peak time interval from a pacing pulse to the maximum peak amplitude. The device is configured to determine a capture type of the pacing pulse based on at least one or both of the maximum peak amplitude and the maximum peak time interval.