The ventricular myocardium in the heart is composed of three cell layer: endocardial, mid-myocardial and epicardial cells. A specific group of myocardial cells termed as M-cells exists in the deep sub-endocardium and mid-myocardium that have a longer action potential duration in comparison to other cell types. A method and system have been provided for analyzing cardiac activity by modelling myocardial cells (M-cells). The method comprises preparing a computational tool that will allow biologists to analyze and retrieve cardiac cellular information automatically and enable discovering of relationships between cellular and cardiovascular system utilizing the M-cells. The method is configured to understand how the properties of M-cells affect the generation of T-wave and how they contribute to arrhythmogenesis in short QT syndrome 2. Pseudo ECGs is created by exciting the tissue in order to analyze the morphology of the T-wave.

Provided is a film-type biomedical signal measuring apparatus configured in a such a way that a plurality of metallic thin film electrodes and a circuit unit are formed on a film-type piezoelectric element so as to easily attach the apparatus to the skin and an electrical signal as well as an electrical signal of a human body is simultaneously measured using the plurality of metallic thin film electrodes and the circuit unit. Accordingly, the film-type biomedical signal measuring apparatus simultaneously measures electrocardiogram (ECG) and ballistocardiogram (BCG) from the simultaneously measured electrical signal and vibration signal of the human body and extracts biomedical information of various types of health indexes such as a heart rate, a stress index, BCG, a blood pressure, an amount of physical activity, a respiration rate, and VO.sub.2max from the two different biomedical signals.

A method may include receiving, at a processor, a first electromagnetic radiation signal and a second electromagnetic radiation signal from a regional oximetry sensor having two or more detectors and two or more emitters. The method may also include receiving, at the processor, a trigger signal that has a frequency corresponding to a periodic physical activity of a patient. Additionally, the method may include generating, via the processor, one or more ensemble averaged signals based at least in part on the first and second electromagnetic radiation signals and the trigger signal. Further, the method may include calculating, via the processor, a regional oxygen saturation value based at least in part on the one or more ensemble averaged signals and displaying, via a display, the regional oxygen saturation value.

A photoacoustic apparatus according to the present invention is a photoacoustic apparatus for obtaining image data based on an acoustic wave generated by irradiating an object with light of a first wavelength and light of a second wavelength which is different from the first wavelength, the photoacoustic apparatus including a processing unit configured to: obtain a first image data group corresponding to the first wavelength generated based on an acoustic wave generated by irradiating the object with light of the first wavelength a plurality of times, obtain first positional deviation information corresponding to an irradiation timing with the light of the first wavelength on the basis of a first image data group corresponding to the first wavelength, and obtain second positional deviation information corresponding to an irradiation timing with the light of the second wavelength on the basis of the first positional deviation information.

A method for detecting wheeze from an audio respiratory signal comprises capturing the audio respiratory signal from a subject using a microphone. Further, the method comprises recognizing a plurality of breath cycles and a plurality of breath phases from the audio respiratory signal and detecting wheezing from the plurality of breath cycles and the plurality of breath phases. The detecting comprises analyzing a block of interest in the audio respiratory signal, wherein the block of interest comprises a plurality of frames. The detecting further comprises calculating an auto-correlation function (ACF) for each frame in the block and determining a maximum value of the ACF calculated for each frame in the block. Finally, the detecting comprises analyzing the maximum value to detect if wheezing is present in the block.

A sleep assessment system includes a blood flow measurement unit and a assessment unit. The blood flow measurement unit acquires first information related to the blood flow of the user. The assessment unit determines the sleep stage of the user based on the first biological information.

Computer-implemented methods of enabling an on-the-fly generation of at least one user-defined montage from EEG electrodes positioned in a patient's brain, on the patient's brain and/or on the patient's scalp. The methods includes generating a graphical interface to display a view of the patient's brain and/or scalp overlaid with the EEG electrodes, each of which is uniquely identified with reference to its position in the patient's brain, on the patient's brain and/or on the patient's scalp, displaying a tool within the graphical interface for selecting at least one electrode from the displayed EEG electrodes, indicating a reference electrode corresponding to the selected electrode, accessing EEG signals corresponding to the electrode and the reference electrode, and generating another graphical interface to display an EEG trace indicative of a comparison of EEG signals of the electrode and the reference electrode.

A subject's Default Mode Network is accessed through corresponding measurements of the Micro-Coherence Oximetry Network Strength (MCO-S). An associated MCO-S system (100) includes a wearable (102), a user device (112) and a processing platform (123). The wearable (102) collects subject information sufficient to enable monitoring and optimization of the subject's Default Mode Network include sensors such as pulse oximetry instrumentation and EEG electrodes to obtain brainwave data, oxygen saturation data, heart rate variability data, and galvanic skin conductance data. Information from the sensors may be communicated to a user device (112), such as a cell phone or VR headset. The user device (112) communicates with a remote processing platform (123) that may execute artificial intelligence functionality and other logic in connection with assessing the patient's micro-coherence network strength and optimizing behavior modification protocols in relation to attributes and objectives of the subject.

Techniques for measuring metabolic tissue state and oxygenation in human or animal models, through optical techniques capable of simultaneous measurement at single region of interest. Simultaneously measuring CCO, oxygenated hemoglobin (HbO), and deoxygenated (HbR) hemoglobin is performed and metabolic activity of the tissue is determined. The methods employ a super-continuum light source and a probe to deliver light to the individual, and reflected light from the individual is analyzed to determine the metabolic function of the individual.

A biological information displaying apparatus according to an embodiment includes a picture obtaining apparatus and a processor. The picture obtaining apparatus obtains a picture signal of a predetermined site of a subject as a moving image. The processor generates a hue moving image by extracting a luminance or an image-based photoplethysmogram (iPPG) related to a pulse wave for each pixel of the moving image and assigning a hue in accordance with a value of luminance information or iPPG information. The processor displays the generated hue moving image such that the hue moving image is superimposed on an image of the subject.