An oximetry device sealed in a sheath directs a user to allow the oximetry device to make oximetry readings at a number of different tissue locations of a patient and average two or more of the oximetry readings by directing the lifts and placements of the oximetry device and sheath to and from the different tissue locations and detecting the lift and placements. The averages are generated and displayed on a display of the device for the oximetry readings if the lifts are made while use directions for the lifts are displayed on a display of the oximetry device. The averages are not generated if the lifts are not made while the user directions for the lifts are not displayed. The averages are simultaneously displayed with the oximetry readings which are instantaneous measurement for patient tissue.

A method of identifying and locating tissue abnormalities in a biological tissue includes irradiating an electromagnetic signal, via a probe defining a transmitting probe, in the vicinity of a biological tissue. The irradiated electromagnetic signal is received at a probe, defining a receiving probe, after the signal is scattered/reflected by the biological tissue. Blood flow information pertaining to the biological tissue is provided. Based on the received irradiated electromagnetic signal and the blood flow information, tissue properties of the biological tissue are reconstructed. A tracking unit determines the position of at least one of the transmitting probe and the receiving probe while the step of receiving is being carried out, the at least one probe defining a tracked probe. The reconstructed tissue properties are correlated with the determined probe position so that tissue abnormalities can be identified and spatially located.

The present application describes a Personal Hand-Held Monitor (PHHM) of the type described in WO 2013/002165, WO 2014/125431, and International Patent Application No. PCT/EP2015/079888, with improved aspects to find indicators of health, and other improvements that facilitate its construction and calibration.

A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images.

Embodiment provides a terminal which comprises at least one processor. The at least one processor is configured to: obtain first biometric feature information of a measured target, where the first biometric feature information includes a pulse wave signal and/or an electrocardio signal of the measured target; obtain a first status of the measured target according to the first biometric feature information of the measured target; determine blood pressure calculation policy of the measured target according to the first status of the measured target; and determine a blood pressure value of the measured target according to the blood pressure calculation policy and the first biometric feature information of the measured target.

Systems and methods for monitoring food intake include an air pressure sensor for detecting ear canal deformation, according to some implementations. For example, the air pressure sensor detects a change in air pressure in the ear canal resulting from mandible movement. Other implementations include systems and methods for monitoring food intake that include a temporalis muscle activity sensor for detecting temporalis muscle activity, wherein at least a portion of the temporalis muscle activity sensor is coupled adjacent a temple portion of eyeglasses and disposed between the temple tip and the frame end piece. The temporalis muscle activity sensor may include an accelerometer, for example, for detecting movement of the temple portion due to mandibular movement from chewing.

In a method for extracting physiological data of an object under examination from ECG signals as part of MR imaging, raw ECG data comprising ECG signals may be captured from at least three electrodes located at different positions on an object under examination. The raw ECG data may be processed, which may include performing a first filtering using a first filter configured to extract an electrocardiogram, performing a second filtering using a second filter configured to identify a heartbeat, performing a third filtering using a third filter configured to extract and/or represent a respiratory movement, and/or performing a fourth filtering using a fourth filter configured to identify breathing. The processed raw ECG data including physiological data of the object under examination may be provided as an output.

Methods, systems, and apparatuses for determining an indication of pain of a user are disclosed. Electrodermal activity (EDA) data from a sensor may be received. The EDA data may be indicative of one or more physiological signals derived from sweat gland activity of the user. Index values may be determined based on the EDA data. The index values may be compared to a threshold to determine if one or more of the values of the index value satisfies the threshold. Satisfying the threshold may indicate a pain in the user, a pain level for the user and/or a source of pain within the user. The indication may be caused to be output so that the user or others may be informed of an objective measurement of the pain in the user.

A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images.

An apparatus for estimating bio-information, includes a sensor including a cover having a transmitting area provided at a center of the cover, and non-transmitting areas provided at both edges of the cover, a light source configured to emit light onto an object that is in contact with the cover, and a detector configured to detect a first optical signal of the emitted light that is scattered or reflected from the object after passing through the transmitting area, and a second optical signal of the emitted light that is reflected from the non-transmitting areas. The apparatus further includes a processor configured to estimate bio-information, based on the detected first optical signal and the detected second optical signal.