A system, method, and apparatus for displaying a fused reconstructed image with a multidimensional image are disclosed. An example imaging system receives a selection corresponding to a portion of a displayed multidimensional visualization of a surgical site. At the selected portion of the multidimensional visualization, the imaging system displays a portion of a three-dimensional image which corresponds to the selected multidimensional visualization such that the displayed portion of the at least one of the three-dimensional image or model is fused with the displayed multidimensional visualization.

A method includes registering a joint of a patient in physical space with a model of the joint in virtual space and planning a planned placement of an implant to be implanted in the joint by performing a soft tissue assessment of the joint and fitting a representation of the implant relative to the model of the joint based on a result of the soft tissue assessment. The method also includes providing, based on the planned placement, a limit on movement of a surgical tool to facilitate preparation of the joint to receive the implant in the planned placement.

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

An enterprise system and method for maintaining and transitioning humans to a human-like self-reliant entity is presented. Said system including at least one a biological, biomechatronic, and mechatronic entity with a biological or artificial neural network to at least one transform or maintain. Embodiments are provided to assist in the transition of human between a biological state to a bio-mechatronic and mechatronic entity. Said entity's biological, biomechatronic, and mechatronic subsystems are configured to communicate and interact with one another in order for said enterprise system to manage, configure, maintain, and sustain said entity throughout the entity's life-cycle. Subsystem embodiments and components supported by the enterprise system are presented.

An apparatus may comprise a glasses frame configured to be worn on a user's head; a button on the frame; a camera on the frame configured to capture an image when a user touches the button; and a transceiver configured to transmit the image wirelessly to a separate device.

Holographic image-guidance can be used to track an interventional device during a non-vascular percutaneous procedure. The holographic image guidance can be provided by a head-mounted device by transforming tracking data and body image data to a common coordinate system and creating a holographic display relative to a patient's body to track the interventional device during the non-vascular percutaneous procedure. The holographic display can also include graphics to provide guidance for the physical interventional device as it travels through the patient's anatomy.

An optical imaging system capable of performing holographic imaging through a multimode optical fiber. Images of an object acquired by the system using different object-illumination conditions can advantageously be used to obtain a holographic image with reduced speckle contrast therein. Additionally, a beat-frequency map of the object acquired by the system using optical-reflectometry measurements therein can be used to augment the depth information of the holographic image for more-detailed three-dimensional rendering of the object for the user. Digital back-propagation techniques may be applied to reduce blurring in the holographic image and in the depth information caused, e.g., by modal dispersion and mode mixing in the multimode optical fiber. Some embodiments may also provide the capability for polarization-sensitive holographic imaging in different spectral regions of light. An example embodiment of the disclosed optical imaging system may be used as a holographic endoscope for medical or industrial applications.

A spinal disorder diagnosis and treatment planning system is provided. The diagnosis and treatment planning system includes a mixed reality holographic display including at least one processor, at least one camera, at least one sensor, and being configured to acquire data points corresponding to a surface of a body adjacent to vertebral tissue. A computer database is configured to transmit imaging of the body including the vertebral tissue to the mixed reality holographic display. The mixed reality holographic display is configured to display a first holographic image of the vertebral tissue superimposed with a body image including the surface. Methods are also disclosed.

A method for spinal disorder diagnosis and treatment planning comprising the steps of: imaging a body including vertebral tissue; acquiring data points corresponding to a surface of the body adjacent to the vertebral tissue with a mixed reality holographic display; transmitting the imaging to a computer database; superimposing a first holographic image of the vertebral tissue with a body image including the surface; and displaying the first holographic image and the body image with the mixed reality holographic display. Systems, spinal constructs, implants and surgical instruments are disclosed.

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.