A system and method include acquisition of a plurality of projection images of a subject, each of the projection images associated with a respective projection angle, determination, for each of the projection images, of a center-of-light location in a first image region, determination of a local fluctuation measure based on the determined center-of-light locations, and determination of a quality measure associated with the plurality of projection images based on the local fluctuation measure.

The present disclosure is related to systems and methods for reconstructing a positron emission tomography (PET) image. The method includes obtaining PET data of a subject. The PET data may correspond to a plurality of voxels in a reconstructed image domain. The method includes obtaining a motion signal of the subject. The method includes obtaining motion amplitude data. The motion amplitude data may indicate a motion range for each voxel of the plurality of voxels. The method includes determining gating data based at least in part on the motion amplitude data. The gating data may include useful percentage counts each of which corresponds to at least one voxel of the plurality of voxels. The method includes gating the PET data based on the gating data and the motion signal. The method includes reconstructing a PET image of the subject based on the gated PET data.

A method for detecting or ruling out non-small cell lung cancer (NS-CLC) in a patient comprises: (a) administering to a patient a detectable amount of a compound of formula (I): Formula (I) wherein the compound is targeted to any NSCLC tumor in the patient; and (b) acquiring an image to detect the presence or absence of any NSCLC tumor in the patient, wherein at least one of the atoms in formula (I) is replaced with .sup.11C, .sup.13N, .sup.15O, .sup.18F, .sup.34mCI, .sup.38K, .sup.45Ti, .sup.51Mn, .sup.52Mn, .sup.52Fe, .sup.55Co, .sup.60CU, .sup.61Cu, .sup.62Cu, .sup.64Cu, .sup.66Ga, .sup.68Ga, .sup.71As, .sup.72As, .sup.74As, .sup.75Br, .sup.75Br, .sup.76Br, .sup.82Rb, .sup.86Y, .sup.89Zr, .sup.90Nb, .sup.94mTc, .sup.110mIn, .sup.118Sb, .sup.120I, .sup.121I, .sup.122I, and .sup.124I.

##STR00001##

An object detection device that detects a specific object included in an input image includes a first candidate region specifying unit that specifies a first candidate region in which an object candidate is included from a first input image obtained by imaging a subject in a first posture, a second candidate region specifying unit that specifies a second candidate region in which an object candidate is included from a second input image obtained by imaging the subject in a second posture different from the first posture, a deformation displacement field generation unit that generates a deformation displacement field between the first input image and the second input image, a coordinate transformation unit that transforms a coordinate of the second candidate region to a coordinate of the first posture based on the deformation displacement field, an association unit that associates the first candidate region with the transformed second candidate region that is close to the first candidate region, and a same object determination unit that determines that the object candidates included in the candidate regions associated with each other by the association unit are the same object and are the specific object.

A gradient coil assembly for a magnetic resonance imaging device is disclosed. The gradient coil assembly comprises a cylindrical carrier with conductors forming three gradient coils associated with three orthogonal physical gradient axes. The cylindrical carrier comprises at least two radial through openings at different angular positions. At least one of the conductors runs through at least one area of the carrier located circumferentially between the through openings.

Systems and methods for dose calibration. A dose calibrator may include one or more radiation sources, one or more solid-state detectors and one or more plates positioned between the one or more radiation sources and the one or more solid-state detectors. The one or more solid-state detectors capture one or more images based on emissions received from the one or more radiation sources through the one or more plates for estimating activity of the one or more radiation sources.

Systems and methods to estimated mean randoms include acquisition of list mode data describing true coincidences and delay coincidences detected by a positron emission tomography scanner during a scan of an object, determination, for each crystal of the positron emission tomography scanner and for each of a plurality of time periods of the scan, of delay coincidences including the crystal based on the list mode data, determination, each crystal, of determine a singles rate associated with each time period based on the delay coincidences determined for the crystal over the time period, determination, for each time period, of determine estimated mean randoms for each of a plurality of pairs of the crystals based on the singles rate associated with the time period for each crystal of the crystal pair, and reconstruction of an image of the object based on the estimated mean randoms for each time period and the detected true coincidences.

An effect of a treatment on an organ, e.g., a lung, is assessed by acquiring a first measurement for each of a plurality of regions of the organ, and then acquiring a second measurement for each of the plurality of regions of the organ, after acquisition of the first measurements. A regional change measurement is obtained for each of the plurality of regions of the organ based on the first measurement and the second measurement of the region. A treatment effect is then determined based the plurality of regional change measurements and treatment information of the treatment delivered to the organ.

A nuclear medicine (NM) multi-head imaging system is provided that includes a gantry, plural detector units mounted to the gantry, and at least one processor operably coupled to at least one of the detector units. The detector units are mounted to the gantry. Each detector unit defines a detector unit position and corresponding view oriented toward a center of the bore. Each detector unit is configured to acquire imaging information over a sweep range corresponding to the corresponding view. The at least one processor is configured to, for each detector unit, determine plural angular positions along the sweep range corresponding to boundaries of the object to be imaged, generate a representation of each angular position for each detector unit position, generate a model based on the angular positions using the representation, and determine scan parameters to be used to image the object using the model.

A multi-axis imaging system comprising an imaging gantry with an imaging axis extending through a bore of the imaging gantry, a support column that supports the imaging gantry on one side of the gantry in a cantilevered manner, and a base that supports the imaging gantry and the support column. The imaging system including a first drive mechanism that translates the gantry in a vertical direction relative to the support column and the base, a second drive mechanism that rotates the gantry with respect to the support column between a first orientation where the imaging axis of the imaging gantry extends in a vertical direction parallel to the support column and a second orientation where the imaging axis of the gantry extends in a horizontal direction parallel with the base, and a third drive mechanism that translates the support column and the gantry in a horizontal direction along the base.