A plurality of image projections are acquired at faster than cardiac rate. A spatiotemporal reconstruction of cardiac frequency angiographic phenomena in three spatial dimensions is generated from two dimensional image projections using physiological coherence at cardiac frequency. Complex valued methods may be used to operate on the plurality of image projections to reconstruct a higher dimensional spatiotemporal object. From a plurality of two spatial dimensional angiographic projections, a 3D spatial reconstruction of moving pulse waves and other cardiac frequency angiographic phenomena is obtained. Reconstruction techniques for angiographic data obtained from biplane angiography devices are also provided herein.

The radiography apparatus includes: an irradiation unit having an irradiation opening through which radiation is emitted; an image receiving unit that has an image receiving surface receiving the radiation emitted from the irradiation unit; an arm that has one end at which the irradiation unit is rotatably supported and the other end at which the image receiving unit is supported in a posture in which the irradiation opening and the image receiving surface face each other; a solenoid that locks the rotation of the irradiation unit with respect to the arm in a facing posture in which the irradiation opening and the image receiving surface face each other; and a control unit that permits the moving image capture irradiation in a state in which the rotation of the irradiation unit is locked and prohibits the moving image capture irradiation in a state in which the rotation is unlocked.

The invention relates to a system for determining an optimal position of a surgical instrument relative to a patient's bone tracker, the system comprising:—a medical imaging system configured to acquire at least one cone beam computed tomography intraoperative image of the patient;—a localization device;—a computer configured to receive images from the medical imaging system and localization data from the localization device and to implement the following method: the method comprising: ⋅(a) receiving at least one preoperative 2D X-ray image of the bone while the patient is in a position of interest; ⋅(b) acquiring an intraoperative 3D medical image of the bone by cone beam computed tomography while the patient is in an operative position different from the position of interest, the 3D image being registered with the coordinate system of the bone tracker; ⋅(c) registering the intraoperative 3D medical image onto the at least one preoperative 2D X-ray image, so as to obtain a registered 3D image representing the bone in the position of interest; ⋅(d) planning a surgical procedure on the registered 3D medical image taking into account said position of interest; ⋅(e) determining an optimal position of the surgical instrument relative to the patient's bone tracker for implementing said planned surgical procedure.

A radiation system may include a treatment assembly including a first radiation source, a second radiation source, and a first radiation detector. The first radiation source may be configured to deliver a treatment beam covering a treatment region of the radiation system, and the treatment region may be located in a bore of the radiation system. The second radiation source may be configured to deliver a first imaging beam covering a first imaging region of the radiation system, and may be mounted rotatably on a first side of the treatment assembly. The first radiation detector may be configured to detect at least a portion of the first imaging beam, and may be mounted rotatably on a second side of the treatment assembly. The treatment assembly, the second radiation source, and the first radiation detector may be positioned such that the treatment region is addressable for the radiation system.

A radiation therapy system comprising a therapeutic radiation system (e.g., an MV X-ray source, and/or a linac) and a co-planar imaging system (e.g., a kV X-ray system) on a fast rotating ring gantry frame. The therapeutic radiation system and the imaging system are separated by a gantry angle, and the gantry frame may rotate in a direction such that the imaging system leads the MV system. The radiation sources of both the therapeutic and imaging radiation systems are each collimated by a dynamic multi-leaf collimator (DMLC) disposed in the beam path of the MV X-ray source and the kV X-ray source, respectively. In one variation, the imaging system identifies patient tumor(s) positions in real-time. The DMLC for the imaging radiation source limits the kV X-ray beam spread to the tumor(s) and/or immediate tumor regions, and helps to reduce irradiation of healthy tissue (e.g., reduce the dose-area product).

The invention concerns a method for obtaining operating parameters for x-ray imaging a patients maxillofacial region, the method comprising: —identifying a patients maxillofacial first region of interest ROI1, —determining a height of a horizontal plane of said patients maxillofacial first region of interest ROI1 when the patient is in an occlusion position or bites a patient positioning accessory, said horizontal plane passing through the teeth and the bones of the jaw, —acquiring through a slit-shaped collimator window a first set of data relative to said patients maxillofacial first region of interest ROI1 including the horizontal plane using x-ray CBCT imaging and a first x-ray dose, said first set of data being suitable for generating a CBCT slice, —reconstructing the CBCT slice comprising the horizontal plane based on the first set of data relative to the patients maxillofacial first region of interest ROI1, —obtaining operating parameters for an x-ray imaging apparatus based on the reconstructed CBCT slice in view of acquiring a second set of data of a patients maxillofacial second region of interest ROI2 using a second x-ray dose, the first x-ray dose being lower than the second x-ray dose.

The invention concerns a method for obtaining operating parameters for an x-ray CBCT imaging apparatus in view of acquiring a set of data of a patient's maxillofacial region. The method comprises: identifying a patient's maxillofacial first region of interest (ROI1), determining a height of a horizontal plane of said patient's maxillofacial first region of interest (ROI1) when the patient is in an occlusion position or bites a patient positioning accessory, acquiring through a slit-shaped collimator window a first set of data relative to said patient's maxillofacial first region of interest (ROI1) including the horizontal plane using x-ray CBCT imaging, reconstructing an axial CBCT slice comprising the horizontal plane based on the first set of data relative to the patient's maxillofacial first region of interest (ROI1), displaying the reconstructed axial CBCT slice of the patients maxillofacial first region of interest (ROI1) from the acquired first set of data, defining at least partially a second region of interest (ROI2) based on the displayed reconstructed axial CBCT slice of the patient's maxillofacial first region of interest (ROI1) and intersecting the latter, obtaining operating parameters for an x-ray CBCT imaging apparatus based on at least the defined second region of interest (ROI2) in view of acquiring a second set of data including the defined second region of interest (ROI2).

Provided is a simulation phantom including a simulated target volume and a simulated normal tissue encasing the simulated target volume, wherein the simulated target volume and a portion of the simulated normal tissue abutting the simulated target volume have a first characteristic to enable the simulation phantom to be imaged on a first imaging device, and the simulated target volume and the portion of the simulated normal tissue abutting the simulated target volume further have a second characteristic to enable the simulation phantom to be imaged on a second imaging device different from the first imaging device.

A method of manufacturing customized ceramic labial/lingual orthodontic brackets by digital light processing, said method comprises measuring dentition data of a profile of teeth of a patient, wherein measuring dentition data is performed using a CT scanner or intra-oral scanner, based on the dentition data, creating a three dimensional computer-assisted design (3D CAD) model of the patient's teeth using reverse engineering, and saving the 3D CAD model on a computer, designing a 3D CAD bracket structure model for a single labial or lingual bracket structure, importing the 3D CAD bracket structure model into a Digital Light Processing (DLP) machine, directly producing the bracket by layer manufacturing.

An improved x-ray cone-beam CT image reconstruction by end-to-end training of a multi-layered neural network is proposed, which employs cone-beam CT images of many patients as input training data, and precalculated scattering projection images of the same patients as output training data. After the training is completed, scattering projection images for a new patient are estimated by inputting a cone-beam CT image of the new patient into the trained multi-layered neural network. Subsequently, scatter-free projection images for the new patient are obtained by subtracting the estimated scattering projection images from measured projection images, beam angle by beam angle. A scatter-free cone-beam CT image is reconstructed from the scatter-free projection images.