An intraocular device for treating glaucoma comprising a treatment probe comprising a distal end region and a proximal end region, the distal end region including a distal end effector sized to penetrate the trabecular meshwork; an outer sheath surrounding at least the proximal end region of the treatment probe; and a drive mechanism operatively coupled to a proximal end of the treatment probe and configured to cause oscillatory movement of the proximal end of the treatment probe to vibrate the distal end effector and agitate intraocular tissue in contact with the distal end effector. Related devices, systems, and methods are provided.

A handle assembly for use with a surgical tack applier includes an actuation assembly and an articulation lever assembly configured to articulate an articulation portion of the surgical tack applier. The actuation assembly includes a motor, an actuation rod, and an actuation switch configured to actuate the motor. The actuation rod has a first end operatively coupled to an output shaft of the motor for concomitant rotation therewith, and a second end operatively coupled to a loading unit of the surgical tack applier such that rotation of the actuation rod ejects a surgical tack from the loading unit. The articulation lever assembly includes an articulation rod operatively coupled with an articulation portion of the surgical tack applier such that axial displacement of the articulation rod causes articulation of the articulation portion, and an articulation lever operatively coupled with the articulation rod.

A fluid control device includes a housing. The housing includes a first main plate, a second main plate, and a side plate connecting the first main plate and the second main plate. The housing has a pump chamber defined by the first main plate, the second main plate, and the side plate. The fluid control device also includes a driver, a first hole that extends through the first main plate or the second main plate, and a first recess formed in the first main plate between a center and a circumference or the second main plate between a center and a circumference.

A phacoemulsification system including a phacoemulsification probe having a probe body, a horn disposed at least partially in the probe body, a needle coupled with the horn and configured to be inserted into an eye, and a piezoelectric actuator disposed in the probe body and configured to vibrate the horn and the needle in a first direction with a stroke length with respect to the probe body; a signal generator configured to generate a drive signal to drive a vibration of the piezoelectric actuator; a stroke measurement apparatus configured to provide indications of the stroke length of the needle over time; and a controller configured to dynamically adjust a frequency of the drive signal so as to maximize the stroke length and maintain mechanical resonance of the needle responsively to the provided indications of the stroke length.

A system includes a needle, an actuator assembly and a generator. The needle is configured to be vibrated so as to emulsify a lens of an eye. The actuator assembly, includes a first actuator, a second actuator and a third actuator, which are distributed around a longitudinal axis of the needle and are configured to vibrate along the longitudinal axis in response to a first driving signal, a second driving signal and a third driving signal, respectively. The generator is configured to generate the first driving signal, the second driving signal and the third driving signal, so as to vibrate the needle in accordance with a predefined pattern.

Described herein are systems, devices and methods that enable dynamic modification of the physicochemical properties of a hydrogel during its in vivo formation and delivery by a catheter. In some example embodiments, an extended endoluminal hydrogel delivery device is employed for delivering a hydrogel within given body cavity, such as within the lumen of a blood vessels. In some example embodiments, a hydrogel precursor, as a non-viscous liquid, is injected through an intravascular catheter and crosslinking of the hydrogel precursor is initiated within a distal region of the catheter. The crosslinking process is controlled, by a control means associated with a distal region of the catheter, to control or modify one or more properties of the hydrogel. The properties may be controlled such that a hydrogel is suitable to embolize the specific target or deliver drugs or other materials beneficial to the site.

The present disclosure relates to an ultrasonic surgical handpiece assembly comprising a surgical handpiece for use with an irrigation sleeve and ultrasonic tip. The surgical handpiece may comprise a piezoelectric transducer disposed within a housing and configured to manipulate the ultrasonic tip. One or more lumens and/or a flex circuit including an antenna may be disposed within the surgical handpiece housing. The lumen(s) may be configured to provide irrigation and/or aspiration to the irrigation sleeve and/or ultrasonic tip. The irrigation sleeve may comprise a second antenna configured to communicate with the ultrasonic handpiece antenna. The irrigation sleeve may further comprise and an alignment and/or coupling feature configured to removably secure the irrigation sleeve to the housing and orient the second antenna relative to the ultrasonic handpiece antenna. The irrigation sleeve may further comprise a lumen for supplying irrigation and/or aspiration to the ultrasonic tip.

A modular surgical instrument system that comprises modular components and a control circuit electrically couplable to the modular components. The modular components comprise a shaft and a handle assembly. The handle assembly comprises a disposable outer housing. The disposable outer housing is movable between an open configuration and a closed configuration. The handle assembly further comprises a control inner core receivable inside the disposable outer housing in the open configuration. The disposable outer housing is configured to isolate the control inner core in the closed configuration. The modular components further comprise a loading unit releasably couplable to the shaft and a staple cartridge releasably couplable to an end effector. The loading unit comprises the end effector. The control circuit is configured to generate an interrogation signal, detect a response signal, determine a modular configuration of the modular surgical instrument system, and assess authenticity of the modular configuration.

An ultrasonic surgical instrument comprises a shaft assembly including a waveguide, and an end effector arranged at a distal end of the shaft assembly and including an ultrasonic blade and a clamp arm. The instrument also comprises a base translatably coupled to shaft assembly. The base includes a first mechanical input and a second mechanical input. The instrument further comprises a closure actuation mechanism operatively connected between the first mechanical input and the clamp arm and configured to actuate the clamp arm from an open position toward a closed position upon selective drive of the first mechanical input. The instrument also includes an insertion actuation mechanism operatively connected between the second mechanical input and the shaft assembly and configured to actuate the shaft assembly from a proximal position toward a distal position upon selective drive of the second mechanical input for insertion of the end effector.

A surgical instrument includes a first member defining an axis and having a scraping surface configured to scrape tissue. A second member includes a cutting surface that is rotatable relative to the first member. The second member has a maximum length defined by opposite end surfaces of the second member. The end surfaces are each disposed within the first member. A third member includes an outer surface defining at least a portion of a passageway configured for disposal of the scraped tissue. The third member is fixed with the first member. The cutting surface is rotatable relative to the third member to transfer the scraped tissue along the axis. Systems and methods are disclosed.