A system for endovascularly sealing a perforation of a blood vessel is provided. The system includes a seal configured to radially expand from a constricted configuration to an expanded configuration. In embodiments, the seal is biased to expand to the expanded configuration. The seal includes (i) a covered region including a blood-impermeable cover configured to seal the perforation, and (ii) an uncovered region that is located axially adjacent the covered region, does not include the blood-impermeable cover, and is configured to enable distal blood flow through the seal. In some embodiments, the system further includes a cylindrical sheath disposed about the seal in the constricted configuration and configured to slide axially along an outer surface of the seal to enable the seal to expand from the constricted configuration to the expanded configuration.

A device for sealing an aperture in a tissue includes: a foot including a distal portion configured to be disposed distal to the tissue when the device is implanted in a position to seal the aperture; and a flexible wing positionable against a distal surface of the tissue adjacent the aperture such that the flexible wing is disposed between the distal portion of the foot and the distal surface adjacent the aperture.

The present invention relates to the field of medical device technologies, and more particularly, to a puncturable atrial septal occluder. The main body of the puncturable atrial septal occluder is made by heat setting after integrally weaving a memory wire material. The occluder includes a stent formed by a left disc, a right disc, and a waist connected, a large central through hole penetrating the stent, and a notch formed at the centers of the left and right discs after the penetration. A baffle membrane is provided inside the central through hole. The notch at the center of the right disc is provided with a plurality of connecting wires. One end of each of the plurality of connecting wires is converged and connected to the delivery component, and the other end of each of the plurality of connecting wires is connected to the right disc in a radioactive manner.

The present invention relates generally to a closure system for use in surgical procedures.

A septal closure and port device for implantation in the atrial septum of a patient's heart comprises an expandable frame can comprise a central portion defining a lumen, and first and second opposing end portions. The frame is configured to expand and contract between a compressed, tubular configuration for delivery through the patient's vasculature and an expanded configuration in which the first and second end portions extend radially outwardly from the opposite ends of the central portion. The device can further comprise a valve member supported on the frame and positioned to block at least the flow of blood from the left atrium to the right atrium through the lumen of the frame. The valve member is configured to permit a medical instrument inserted through the lumen and into the left atrium, such as for performing a subsequent medical procedure in the left side of the heart.

An elongate resilient tube of a mesh of shape memory alloy is used to therapeutically occlude an opening in body tissue. The tube is compressible so that it can be delivered to the opening in the body within a catheter. The tube self-expands as it is released from the catheter to contiguously form, sequentially an outer perimeter structure and an inner perimeter structure disposed within the outer perimeter structure to conformingly engage an inner side of the outer perimeter structure, a plate shaped structure, and a flexible connector between them. J-shaped hooks extend from the perimeter structure to flexibly engage tissue of the body opening without piercing the tissue.

A medical implant including an anchor portion including a plurality of arms adapted to engage an internal tissue wall of a body from two opposite faces, wherein the anchor portion is configured such that at least one of the arms does not have an entirely overlapping arm on the other side of the wall and an opening portion adapted to define an opening for blood flow through the internal tissue wall, when the anchor portion engages the wall.

A medical device includes a first end, a second end, and a central segment proximate a middle of the medical device and about which the medical device is symmetrical. The medical device also includes a pair of inner reverse bends spaced from the central segment by a first body plane extending from the central segment to the pair of inner reverse bends in a first longitudinal direction, and a pair of outer reverse bends. The outer reverse bends are spaced from the pair of inner reverse bends by a second body plane extending from the pair of inner reverse bends to the pair of outer reverse bends in a second, opposite longitudinal direction, and the outer reverse bends are spaced from the first and second ends of the medical device by a third body plane extending in the first direction from the outer reverse bends to the first and second ends.

An occluder has a first disk-shaped structure with a grid, wherein the first disk-shaped structure is woven from at least two groups of braided wires, and the two groups of braided wires are crossed to form multiple rings of crossing points. A blocking membrane is also arranged in the disk-shaped structure, with an edge of the blocking membrane connected to the outermost ring of crossing points of the multiple rings of crossing points through a sewing wire, and the number of crossing points in the outermost ring of crossing points sewn with the blocking membrane is smaller than the number of all the crossing points in the outermost ring of the crossing points. The occluder can reduce the possibility of the phenomenon where the edge of the blocking membrane cannot abut against a disk face edge of the occluder, thereby improving the occlusion effect of the occluder.

A method for delivery and deployment of a prosthetic mitral valve into a heart includes inserting an introducer sheath having a prosthetic mitral valve disposed therein in a collapsed configuration into the left atrium of a patient's heart, through a gap between the native mitral valve leaflets, the left ventricle and apex of the heart. An epicardial pad device coupled to the prosthetic valve via a tether is moved distally out of the sheath. The introducer sheath is withdrawn into the left atrium of the heart. An inner delivery sheath is extended distally from within the introducer sheath and disposed within the left atrium. The prosthetic mitral valve is moved distally out of the inner delivery sheath and assumes a biased expanded configuration. The valve is positioned within the mitral annulus of the heart, and secured in place via the tether and epicardial pad device.