The present invention relates generally to agents and devices for promoting hemostasis and, more particularly, to bioresorbable hemostatic pads or patches releasably supported on non-resorbable scaffolds for ease of delivery in the field. A sealant and/or hemostat delivery device comprises a resorbable hemostatic pad having a wound facing side and an opposite back side, with a hemostatic and/or wound sealing agent disposed on the wound facing side; a non-resorbable scaffold having an attachment zone on said scaffold; wherein said hemostatic pad is releasably attached with the back side to the attachment zone. The bond between the scaffold and the resorbable hemostatic pad or wound dressing is either (i) severed prior to removal of the scaffold or (ii) is weakened due to the adhesive bonding them together being moisture-deactivated, or (iii) is released by mechanical disentanglement.

Methods and devices are provided for promoting wound healing. In general, surgical staplers and stapler components are provided having a coating thereon that is configured to selectively control an interaction between at least one matrix metalloproteinase (MMP) inhibitor and an outer surface of the stapler or stapler component.

Devices and methods are provided for stabilizing fasteners post-deployment. Devices and methods are also provided for facilitating ejection of surgical fasteners from a cartridge. Devices and methods are also provided for guiding surgical fasteners. Devices and methods are also provided for facilitating closing and clamping of an end effector of a surgical device. Devices and methods are also provided for securing fasteners and adjunct materials to tissue. Devices and methods are also provided for removably coupling a cartridge to an end effector of a surgical device. Devices and methods are also provided for locking a surgical device based on loading of a fastener cartridge in the surgical device. Devices and methods are provided for adjusting a tissue gap of an end effector of a surgical device. Devices and methods are also provided for manually retracting a drive shaft, drive beam, and associated components.

A circular stapling device includes a handle assembly, an elongated body, an end effector, and one or more buttress members. The elongated body extends from the handle assembly. The end effector is mounted on a distal end of the elongate body and supports the one or more buttress members. A buttress release mechanism operatively coupled to the end effector selectively secures the one or more buttress members to the end effector.

Devices, systems and/or methods for repairing soft tissue adjacent a repair site. In one embodiment, a repair device is delivered with a delivery device system configured to move a cartridge with the repair device disposed therein toward an anvil with soft tissue positioned thereon. The delivery device linearly moves the cartridge toward the anvil with a worm drive positioned within a housing by rotating a thumb wheel disposed around the worm drive. Such linear movement is provided with a finger element extending from the worm drive that is configured to cooperate with an internal surface of the thumb wheel. With this arrangement, upon rotating the thumb wheel, the worm drive rotates with the finger element engaged with the internal surface of the thumb wheel to linearly move the cartridge toward the anvil.

The present invention relates to surgical instruments and methods for enhancing properties of tissue repaired or joined by surgical staples and, more particularly to surgical instruments and methods designed to enhance the properties of repaired or adjoined tissue at a target surgical site, especially when sealing an anastomosis between adjacent intestinal sections so as to improve tissue viability, prevent tissue infection, and to prevent leakage. The present invention further relates to an expandable compression device for application to anastomotically joined tubular tissues, comprising: an upper ring-shaped or disk-shaped flange at a distal end of said device connected to a lower ring-shaped inflatable flange at a proximal end of said device via a hollow cylindrical tubular body, with an opening forming an axial passage through said upper flange, lower flange, and tubular body.

The present invention relates to surgical instruments and methods for enhancing properties of tissue repaired or joined by surgical staples and, more particularly to surgical instruments and methods designed to enhance the properties of repaired or adjoined tissue at a target surgical site, especially when sealing an anastomosis between adjacent intestinal sections so as to improve tissue viability, prevent tissue infection, and to prevent leakage.

A staple is disclosed. The staple includes a crown extending substantially along an axis between a first end and a second end, a first leg extending from the first end of the crown, the first leg ending in a point, and a second leg extending from the second end of the crown, the second leg ending in a point. The first leg and the second leg are deformably moveable between a first configuration and a second configuration. In the first configuration, the first leg and the second leg are positioned substantially parallel with the crown. In the second configuration the first leg and the second leg positioned are substantially perpendicular to the crown. The staple also includes a pad disposed on at least a portion of the crown.

An end effector for use with a surgical fastening instrument is disclosed which comprises a staple cartridge and an anvil. The staple cartridge comprises a cartridge body including a deck and, in addition, fasteners removably stored in the cartridge body, wherein each fastener comprises a base and a leg extending from the base. The anvil comprises a tissue compression surface and forming pockets defined in the tissue compression surface. Each forming pocket comprises a first end configured to receive a staple leg, a second end, a central axis extending between the first end and the second end, a concave turning surface extending between the first end and the second end, and a channel defined in the concave turning surface, wherein the channel is laterally offset from the central axis.

A surgical instrument comprising a lockout is disclosed.