A clipping system for treating tissue a clip with clip arms and an applicator having a flexible member and a control member. Proximal ends of the arms are received within a channel of a capsule. The capsule includes a slot extending from a proximal end of the capsule through a wall thereof. The control member includes a distal end connectable to the arms to move them between the open and closed configurations. A distal end of the flexible member includes a bushing having a distal portion receivable within a proximal end of the capsule. The distal portion includes an engaging tab extending laterally outward therefrom receivable within an engaging portion of the slot, a spring extending along the distal portion and disposed proximally of the engaging tab so that, when the engaging tab is received within the engaging portion, the spring is compressed against a portion of the capsule.

A ligation clip includes a first beam that supports a first alignment member and a second beam that supports a second alignment member. The first and second alignment members receive distal end portions of first and second beam portions of a second ligation clip when the ligation clips are stacked within a multi-fire clip applier to provide stability to the clip stack.

Disclosed are elements for producing a vascular clip and vascular clips produced with these elements. The element is essentially characterized by the fact that it includes a support plate, a clip tab including a gripping face, a unit for securing the clip tab and the edge face of the plate, two substantially identical brackets, each bracket substantially having the shape of a cylinder sector with a thickness Ep and including a through hole with an axis parallel to the generatrix of the cylinder, and a unit to secure the two brackets and the plate in such a way that the axes of the two holes are located on the same straight line perpendicular to the tab and that the opposite faces of the two brackets are set apart from each other by a value equal to the thickness Ep.

A valve repair device for repairing a native heart valve of a patient includes a pair of clasps, where each clasp is configured to attach to native valve leaflet. The ends of the pair of clasps can move away from one another to a partially open position when the native valve leaflets open during a diastolic phase of a cardiac cycle, and the ends of the pair of clasps can move toward one another when the native valve leaflets close during a systolic phase of a cardiac cycle.

Devices and systems to fit around a tissue or organ and methods of using the same. In at least one embodiment of an implantable device of the present disclosure, the implantable device comprises a first engaging component comprising a first rigid inner plate at least partially surrounded by a first flexible coating, a second engaging component comprising a second rigid inner plate at least partially surrounded by a coating selected from the group consisting of the first flexible coating and the second flexible coating, a first c-ring and a second c-ring coupled to the engaging components, and a cover flap coupled to either the first engaging component or the second engaging component and capable of either further coupling to the second engaging component when initially coupled to the first engaging component or further coupling to the first engaging component when initially coupled to the second engaging component.

Methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. A delivery device for staged deployment of an implantable device to a target area. The delivery device includes a deployment handle and one or more lock lines extending from the deployment handle through the catheter to the implantable device, the one or more lock lines being configured to engage with the implantable device to allow locking of the implantable device.

A system for treating tissue includes a clip assembly including a pair of clip arms. Proximal ends of the clip arms are slidably received within a channel of a capsule to be moved between a tissue receiving configuration and a tissue clipping configuration. The system also includes a catheter assembly including a control member extending therethrough. The control member includes a distal end connected to the clip arms to move the clip assembly between the receiving and clipping configurations. The system further includes a coupler releasably coupled to a proximal end of the capsule and configured to be coupled to the distal end of the catheter assembly. The coupler fractures when a proximal force exerted on the coupler via the control member exceeds a first predetermined threshold value to disengage the capsule and deploy the clip assembly.

Disclosed are systems and methods for safely and effectively deploying a hemoclip onto a patient's desired target using a combined hemoclip and endoscopic system. For instance, disclosed is an endoscope that includes a lumen for a hemoclip of the present disclosure to pass through. Additionally, disclosed are hemoclips that are configured to be in a compressed position until the hemoclip is deployed out of an endoscope where it opens into an X-shape. Then, the hemoclip may be clipped onto the target to encapsulate the desired target within the patient. Once the hemoclip is clamped onto the target, the endoscope can move onto the next target for successive deployment and utilization of the hemoclips without manual reload.

The device (1) comprises: A first assembly (6) engageable with a handle under the control of control means for the actuation of the assembly for the placement and attachment of an artificial cord (7) on the papillary muscle (8) of a ruptured cord, said assembly is arranged at the end of a manipulation rod and comprises an elastic staple (9) connected pivotably and removably at the end of the rod so as to pass, under the action of the control means, from a position folded back along the rod to a position swung angularly relative to the rod for coming into place perpendicularly in front of the papillary muscle where the cord must be replaced, the first assembly (6) comprises means for opening the staple (9) in order to, under the action of the command means, anchor the papillary muscle (8) for the ruptured cord, the first assembly (6) comprises means for unlocking with which, under the action of the command means, to release the staple (9), said staple (9) being connected to an artificial cord (7) which goes back in the rod; A second assembly (13) engageable with a handle under the control of control means for the actuation of the assembly for the placement and attachment of the artificial cord (7) to a leaflet (2a) of the valve (2), the second assembly (13) is arranged at the end of the manipulation rod and comprises attachment means (9, 16) intended to slide along the artificial cord (7) and pivotably connected to the end of the rod so as to pass, under the action of the control means, from a position folded back along the rod to a position orthogonal to the rod, where the means of attachment (9, 16) are able, under the action of the command means, to attach the artificial cord (7) to said leaflet (2a).

An external LAA exclusion clip comprises a clipping assembly comprising first and second opposing clip struts each of the clip struts having a tissue-contacting surface and first and second bias surfaces, a bias assembly connecting the first clip strut to the second clip strut to align the first and second clip struts in a strut plane passing through the tissue-contacting surface. The bias assembly comprises at least one first bias spring connected to the first bias surface of the first clip strut and to the first bias surface of the second clip strut and at least one second bias spring connected to the second bias surface of the first clip strut and the second bias surface of the second clip strut. The first bias spring and the second bias spring are configured to permit movement of the first and second clip struts in the strut plane.