Methods and devices for separating an implanted object, such as a pacemaker lead, from tissue surrounding such object in a patient's vasculature system. Specifically, the tissue separating device includes a handle, an elongate sheath and a circular cutting blade that may extend from the distal end of the sheath upon actuating the handle. The elongate sheath, particularly its distal end, includes a non-uniform wall thickness having one or more thicker portions in the outer sheath, particularly the outer cam member, and/or one or more thicker portions in an inner member disposed radially inward of the blade.

A tissue resecting device includes an outer sleeve having an axial bore extending along a longitudinal axis from a proximal end to a distal end and opening to an outer window near the distal end. An inner sleeve is rotatably received in the axial bore of the outer sleeve and has an axial channel adapted for communication with a negative pressure source. A distal housing is attached to a distal end of the inner sleeve and has an annular dielectric portion and a circumferentially adjacent annular metal portion having an inner window with circumferentially spaced-apart sharp cutting edges that opens to the axial channel. An active electrode is carried by the annular dielectric portion, and the inner window is circumferentially spaced-part from the active electrode so that the inner window and the active electrode rotate alternately into alignment with the outer window as the inner sleeve is rotated within the outer sleeve.

A method of implanting a prosthetic mitral valve includes advancing a delivery apparatus into a left side of a patient's heart and deploying a support structure from the delivery apparatus. The support structure extends around native mitral valve leaflets such that the native leaflets are disposed radially within the support structure. The method also includes advancing a prosthetic heart valve within the native leaflets. The prosthetic heart valve is separate from the support structure and includes an annular frame and a valve structure positioned within the annular frame, and prosthetic heart valve is in a radially collapsed configuration. The method further includes expanding the prosthetic heart valve from the radially collapsed configuration to a radially expanded configuration. In the radially expanded configuration, the annular frame of the prosthetic heart valve engages the native leaflets and is separated from the support structure by the native leaflets.

A tissue resecting device includes an elongated shaft having a central axis, a distal end, and an outer surface. An offset housing is mounted on the distal of the shaft and has a tissue-receiving window. The tissue-receiving window is offset radially outwardly from the outer surface of the shaft, and a moveable electrode is configured to move back and forth across the window to resect tissue which extends into the window. The offset housing improves visibility of the cutting window when viewed from endoscopes and other visualization apparatus.

A tissue specimen retrieval device includes a first shaft and a second shaft telescopically movable relative to the first shaft. The second shaft supports an end effector assembly at a distal end portion thereof and is movable relative to the first shaft between a retracted position, wherein the end effector assembly is disposed within the first shaft, and a deployed position, wherein the end effector assembly extends distally from the first shaft. The end effector assembly includes a tissue specimen bag supported by a first arm and a second arm. The first and second arms are configured to open the tissue specimen bag when the second shaft is deployed. A cut-off slider is operably associated with the distal end portion of the second shaft and is configured to sever the tissue specimen bag upon retraction of the second shaft.

The present technology is directed generally to devices, systems, and methods for capturing and cutting fibrous and trabeculated structures (such as synechiae) in vessel lumens. In one embodiment, the present technology includes an intraluminal tissue modifying system configured to capture the fibrous structures, put the fibrous structures in tension, and controllably cut through the fibrous structures without applying appreciable additional force to the vessel wall. The system may include an expandable capture device and a cutting device.

A tissue resecting instrument includes a drive assembly coupled to an inner cutting shaft and configured to drive translation and/or rotation of the inner cutting shaft, a trigger coupled to the drive assembly and configured for manual actuation to drive the drive assembly, a vacuum generator configured to generate vacuum to suction cut tissue through the inner cutting shaft and into the vacuum generator, and a tissue collection cartridge configured to engage the housing. The tissue collection cartridge defines a port configured to communicate with the vacuum generator such that the vacuum generator urges cut tissue from the vacuum generator through the port into the tissue collection cartridge. The tissue collection cartridge may include at least one histological agent disposed therein, may include a fill indicator configured to indicate a fill level of tissue within the tissue collection cartridge, and/or may include a latch configured to seal the port closed.

Methods and devices for separating an implanted object, such as a pacemaker lead, from tissue surrounding such object in a patient's vasculature system. Specifically, the tissue separating device includes a handle, an elongate sheath and a circular cutting blade that may extend from the distal end of the sheath upon actuating the handle. The elongate sheath, particularly its distal end, includes a non-uniform wall thickness having one or more thicker portions in the outer sheath, particularly the outer cam member, and/or one or more thicker portions in an inner member disposed radially inward of the blade.

A tissue resecting instrument includes a housing, an outer shaft extending distally from the housing and defining a window at a distal end potion thereof, an inner cutting shaft extending through the outer shaft, a drive assembly, a trigger, and an adjustable resistance mechanism. The inner cutting shaft is translatable and/or rotatable relative to the outer shaft. The drive assembly is coupled to the inner cutting shaft and configured to drive the translation and/or rotation thereof. Manual actuation of the trigger actuates the drive assembly to drive the translation and/or rotation of the inner cutting shaft. The adjustable resistance mechanism includes a spring coupled between the trigger and the housing, and a control knob operably coupled to the spring to enable adjustment of a resistance to pivoting of the trigger from an un-actuated position to an actuated position.

The invention relates to a cardiac lead extraction device, comprising: a handle; an elongated body having a first proximal end, a first distal end, and a first lumen extending from said first proximal end toward said first distal end, said lumen sized and shaped to fit over a cardiac lead; a controllable bendable flexible portion more flexible that said elongated body and having a second proximal end, a second distal end and a second lumen extending from said second proximal end toward said second distal end, said lumen sized and shaped to fit over a cardiac lead; said second proximal end interconnected to said first distal end; said second distal end interconnected to an operational distal end; wherein said operational distal end comprises at least one lead extraction assistive tool, said lead extraction helping tool is activated by a motor located at said handle or proximally to said handle.