Methods and devices that displace bone or other hard tissue to create a cavity in the tissue. Where such methods and devices rely on a driving mechanism for providing moving of the device to form a profile that improves displacement of the tissue. These methods and devices also allow for creating a path or cavity in bone for insertion of bone cement or other filler to treat a fracture or other condition in the bone. The features relating to the methods and devices described herein can be applied in any region of bone or hard tissue where the tissue or bone is displaced to define a bore or cavity instead of being extracted from the body such as during a drilling or ablation procedure.

A microwave field-detecting needle assembly includes a needle assembly. The needle assembly includes a distal portion, a proximal portion, and a junction member disposed between the distal portion and the proximal portion. The junction member includes a recess defined therein. The needle assembly also includes a rectifier element disposed in the recess. The rectifier element includes a first terminal electrically coupled to the distal portion and a second terminal electrically coupled to the proximal portion.

Devices and methods for delivering fluid to tissue during ablation therapy are described herein. An exemplary device can include an elongate body having an inner lumen, outlet ports, and an ablation element configured to heat tissue. A flow resistance of the elongate body can increase along a length of the elongate body containing the outlet ports in a proximal to distal direction. This can be accomplished by, for example, varying outlet port size or relative spacing, decreasing a cross-sectional area of the inner lumen through which fluid can flow using a flow diverter or tapered inner lumen sidewalls, or limiting a ratio between a total area of the outlet ports and a cross-sectional area of the inner lumen. Adjusting flow resistance of the elongate body can provide more uniform fluid distribution or a desired non-uniform distribution.

Compositions, systems, devices, and methods for performing precise chemical treatment of tissues are disclosed. Systems, devices, and methods for administering a chemical agent to one or more a precise regions within a tissue mass are disclosed. Compositions, systems, devices, and methods for treating targeted regions within a tissue mass are disclosed. Systems, devices, and methods for identifying, localizing, monitoring neural traffic in the vicinity of, quantifying neural traffic in the vicinity of, and mapping neural traffic near targeted regions within a tissue mass are disclosed.

A cryoablation temperature control method, system and computer-readable storage medium. The method is used to control a temperature of the interior of a cryoablation balloon and includes: generating, based on an acquired real-time temperature value and a preset target temperature value of the interior of the balloon and/or a real-time gas flow rate value and a target gas flow rate value of a gas recovery passage in a gas outlet channel for the balloon, a first target liquid inlet pressure control signal for controlling a liquid supply flow rate of a high-pressure proportional valve in a liquid supply channel for the balloon; generating, based on an acquired real-time gas pressure value on, and a preset target gas pressure value for, a gas outlet side of the balloon, a first target gas outlet pressure control signal for controlling a gas outlet flow rate of a low-pressure proportional valve in the gas outlet channel for the balloon and for coordinating with the first target liquid inlet pressure control signal to perform control so that a pressure in the interior of the balloon is within a predefined safe pressure threshold value range and the temperature of the interior of the balloon is brought to and/or maintained at the target temperature value. This application allows accurate temperature control within a wide range and a short procedure time.

An injectate delivery device for expanding tissue is provided. The injectate delivery device comprises: at least one fluid delivery tube comprising a proximal end, a distal end and a lumen therebetween; at least one fluid delivery element in fluid communication with the at least one fluid delivery tube lumen; a radially expanding element comprising the at least one fluid delivery element; a supply of vacuum constructed and arranged to cause tissue to tend toward the at least one fluid delivery element; and at least one control constructed and arranged to perform a function. The at least one control can be constructed and arranged to expand the radially expandable element and activate the supply of vacuum. Systems and method of injectate delivery are also provided.

An arthroscopic or other medical device includes an elongate shaft having a proximal end and a working end. At least one electrode for treating tissue is located at the working end of the shaft, and a fluid outflow path extends proximally from the working end through a first channel portion in the shaft. A handpiece is coupled to the proximal end of the shaft and has a body with a second channel portion formed along an axis therein. The second channel is receives a heated or other outflow from a proximal end of the first channel in the shaft, and the second channel runs along an axis of the handpiece. A thin wall sleeve is located in the handpiece so that it surrounds at least a portion of the second channel. The thin wall sleeve is surrounded by an air gap or otherwise provides a thermal barrier between an exterior surface of the thin wall sleeve and an inner surface of the body of the handpiece in order to limit heat transfer from the heated or other fluid outflow through the second channel.

Devices and methods for treating rhinitis are provided. An integrated therapy and imaging device is provided for single handheld use. The device may have a hollow elongated cannula, a therapeutic element coupled to a distal portion of the cannula, an imaging assembly coupled to the cannula to provide visualization of the therapeutic element, and an articulating region operably coupled to the imaging assembly to articulate the imaging assembly. The imaging assembly may be articulated so as to translate vertically, laterally, axially, and/or rotationally.

A catheter and catheter system can use energy tailored for remodeling and/or removal of target material proximate to a body lumen, often of stenotic material or tissue in the luminal wall of a blood vessel of a patient. An elongate flexible catheter body with a radially expendable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radically engage the luminal wall when the structure expands. Feedback using one or parameters of voltage, current, power, temperature, impedance magnitude, impedance phase angle, and frequency may be used to selectively control the delivery of energy.

Described herein are various implementations of systems and methods for accessing and modulating tissue (for example, systems and methods for accessing and ablating nerves or other tissue within or surrounding a vertebral body to treat chronic lower back pain). Assessment of vertebral endplate degeneration or defects (e.g., pre-Modic changes) to facilitate identification of treatment sites and protocols are also provided in several embodiments. Several embodiments comprise the use of biomarkers to confirm or otherwise assess ablation, pain relief, efficacy of treatment, etc. Some embodiments include robotic elements for, as an example, facilitating robotically controlled access, navigation, imaging, and/or treatment.