Tumors in portions of a subject's body that have a longitudinal axis (e.g., the torso, head, and arm) can be treated with TTFields by affixing first and second sets of electrodes at respective positions that are longitudinally prior to and subsequent to a target region. An AC voltage with a frequency of 100-500 kHz is applied between these sets of electrodes. This imposes an AC electric field with field lines that run through the target region longitudinally. The field strength is at least 1 V/cm in at least a portion of the target region. In some embodiments, this approach is combined with the application of AC electric fields through the target region in a lateral direction (e.g., front to back and/or side to side) in order to apply AC electric fields with different orientations to the target region.

A method for performing an electrosurgical procedure at a surgical site on a patient includes continually sensing electrical and physical properties proximate the surgical site that includes acquiring readings of tissue electrical impedance with respect to time at the surgical site; identifying the minima and maxima of the impedance readings with respect to time; and correlating the minima and/or the maxima of the impedance readings with hydration level and/or hydraulic conductivity in the tissue at the surgical site. The method also includes controlling the application of electrosurgical energy to the surgical site to vary energy delivery based on the step of correlating the minima and/or the maxima of the impedance readings with the hydration level/or and the hydraulic conductivity in the tissue at the surgical site. The process may be an ablation process.

A medical device can include a surgical device (102) that can include an elongated shaft (118) configured to be guided via an access stabilizer (1224). The device can include a housing mechanically coupled to the shaft. The device can include an electrical port (122) at least partially around the shaft, the shaft extending through and able to longitudinally translate through an opening in the electrical port. The device can include one or more electrical interconnects (120) configured to receive an electrical signal from or provide the electrical signal to the electrical port.

A vapor delivery system and method is provided that is adapted for treating prostate tissue. The vapor delivery system includes a vapor delivery needle configured to deliver condensable vapor energy to tissue. In one method, the vapor delivery system is advanced transurethrally into the patient to access the prostate tissue. The vapor delivery system includes a generator unit and an inductive heating system to produce a high quality vapor for delivery to tissue. Methods of use are also provided.

A body orifice remodeling device includes a cylindrical handpiece having a defined length which is adapted to be inserted into the body orifice and an elongated monopolar electrode mounted outside on the circumference of the cylindrical handpiece and extending substantially along the length of the handpiece. A source of radio frequency (RF) energy in the handpiece is configured to generate RF energy to the elongated monopolar electrode; and a source of electromagnetic stimulation energy (EMagS) in the handpiece is configured to generate (EMagS) energy.

System and methods of an electrosurgical controller having multiple modes of operation that are configured for treatment of a specific targeted tissue type and the electrosurgical effect desired where the treatment and effect are provided by a single controller and an electrosurgical probe. The electrosurgical controller includes an integrated fluid control apparatus or pump where activation of the controller allows for selective energy delivery and corresponding fluid volume flow rates. The electrosurgical probe includes a fluid transport lumen and is in communication with the controller and the pump for operation of the probe in the various user selected modes with accompanying energy delivery and fluid control directed to the desired treatment and surgical effect.

A device, system, and method for treating an area of tissue and evaluating lesion formation and quality. The system may include a medical device having a plurality of mapping electrodes on a treatment element, the plurality of mapping electrodes being configured to record from the area of tissue at least one of unipolar impedance measurements, bipolar impedance measurements, local electrical activity, and pace threshold measurements before, during, and after circulation of the cryogenic fluid within the treatment element. These measurements may be transmitted to a control unit having processing circuitry configured to compare pre-treatment measurements, in-treatment measurements, and/or post-treatment measurements to each other and/or to threshold values to determine occlusion and/or lesion quality, such as lesion transmurality.

A method for performing an electrosurgical procedure at a surgical site on a patient includes continually sensing electrical and physical properties proximate the surgical site that includes acquiring readings of tissue electrical impedance with respect to time at the surgical site; identifying the minima and maxima of the impedance readings with respect to time; and correlating the minima and/or the maxima of the impedance readings with hydration level and/or hydraulic conductivity in the tissue at the surgical site. The method also includes controlling the application of electrosurgical energy to the surgical site to vary energy delivery based on the step of correlating the minima and/or the maxima of the impedance readings with the hydration level/or and the hydraulic conductivity in the tissue at the surgical site. The process may be an ablation process.

A method for re-configuring a biomedical laser device. The biomedical laser device is pre-configured to be operable in one or more operational modes, and is provided with set of operational parameters that are employed for at least one of: given medical procedure, given medical treatment, activation of given drug, illumination of given dye. The method includes collecting information indicative of light output properties of biomedical laser device measured during given operational mode; detecting deviation in measured light output properties with respect to predefined light output properties for given operational mode; determining new set of operational parameters that are to be employed for at least one of: new medical procedure, new medical treatment, activation of new drug, illumination of new dye; and sending new set of operational parameters to biomedical laser device for re-configuring biomedical laser device to be operable in a new operational mode.

A device, system, and method for treating an area of tissue and evaluating lesion formation and quality. The system may include a medical device having a plurality of mapping electrodes on a treatment element, the plurality of mapping electrodes being configured to record from the area of tissue at least one of unipolar impedance measurements, bipolar impedance measurements, local electrical activity, and pace threshold measurements before, during, and after circulation of the cryogenic fluid within the treatment element. These measurements may be transmitted to a control unit having processing circuitry configured to compare pre-treatment measurements, in-treatment measurements, and/or post-treatment measurements to each other and/or to threshold values to determine occlusion and/or lesion quality, such as lesion transmurality.