A controller for an electrosurgical generator includes an RF inverter, a signal processor, a software compensator, a hardware compensator, and an RF inverter controller. The RF inverter generates an electrosurgical waveform and the signal processor outputs a measured value of at least one of a voltage, a current, or power of the electrosurgical waveform. The software compensator generates a desired value for at least one of the voltage, the current, or the power of the electrosurgical waveform, and the hardware compensator generates a phase shift based on the measured value and the desired value. The RF inverter controller generates a pulse-width modulation (PWM) signal based on the phase shift to control the RF inverter.

A sine wave generator includes a resonator circuit, a control circuit and a pulse generator. The resonator circuit is configured to receive energy pulses and to generate a resonator sinusoidal signal responsively to the energy pulses. The control circuit is configured to estimate a signal measure of the resonator sinusoidal signal, or of a signal derived from the resonator sinusoidal signal. The pulse generator is configured to generate the energy pulses responsive to the signal measure estimated by the control circuit, and to drive the resonator circuit with the energy pulses.

Disclosed herein is an electroporation system including a catheter shaft, at least one electrode coupled to the catheter shaft at a distal end thereof, and an electroporation generator coupled in communication with the at least one electrode. The electroporation generator configured to supply a biphasic pulse signal to the at least one electrode. The biphasic pulse signal includes a first phase having a first polarity and a first pulse duration, and a second phase having a second polarity opposite to the first polarity, and a second pulse duration. Each of the first phase and second phase has a voltage amplitude of at least 500 volts and a pulse duration of less than 20 microseconds. The second phase is generated at a non-zero interval following the first phase.

Disclosed are systems, devices, and methods for interdigitation of waveforms for dual-output electrosurgical generators. Such methods may comprise outputting DC energy from a power supply, converting DC energy from the power supply, by a plurality of amplifiers coupled to the power supply, into a plurality of RF waveforms, and controlling the plurality of RF amplifiers to interdigitate the first and second RF waveforms.

A dermal conditioning device for creating at feast one fissure, in a stratum corneum layer of an area of skirt, comprising: a non-invasive fissuring generator; a controller coupled to the non-invasive skin fissuring generator, a power supply coupled to the non-invasive skin fissuring generator and the controller; and a housing encasing the non-invasive skin fissuring generator and the controller, wherein the controller controls the non-invasive skin fissuring generator to: generate at least one signal, and apply the at least one signal to dehydrate the area of skin, and stress the external surface of the stratum corneum layer of the area of skin, the stress calibrated to produce a strain on the stratum corneum layer causing a formation of at least one fissure in the stratum corneum layer when the area of skin is dehydrated, while maintaining a pre-fissure immune status of the area of skin.

Optical energy-based methods and apparatus for sealing vascular tissue involves deforming vascular tissue to bring different layers of the vascular tissue into contact each other and illuminating the vascular tissue with a light beam having at least one portion of its spectrum overlapping with the absorption spectrum of the vascular tissue. The apparatus may include two deforming members configured to deform the vascular tissue placed between the deforming members. The apparatus may also include an optical system that has a light source configured to generate light, a light distribution element configured to distribute the light across the vascular tissue, and a light guide configured to guide the light from the light source to the light distribution element. The apparatus may further include a cutting member configured to cut the vascular tissue and to illuminate the vascular tissue with light to seal at least one cut surface of the vascular tissue.

A surgical instrument end effector assembly includes a first jaw member and a second jaw member. The second jaw member includes an ultrasonic blade body and first and second electrodes disposed on either side of the ultrasonic blade body and extending longitudinally along a majority of a length of the ultrasonic blade body. The ultrasonic blade body is adapted to receive ultrasonic energy from an ultrasonic waveguide. The first and second electrodes taper in width proximally to distally and are adapted to connect to a source of electrosurgical energy. The first jaw member is movable relative to the second jaw member between a spaced-apart position and an approximated position for grasping tissue therebetween.

A Radio Frequency (RF) ablation system includes a signal generator, control circuitry, a plurality of non-linear amplifiers, and a processor. The signal generator is configured to generate an RF signal having a given frequency. The control circuitry is configured to set phases and amplitudes of a plurality of replicas of the RF signal generated by the signal generator. The plurality of non-linear amplifiers is configured to amplify the plurality of replicas of the RF signal, and to drive a respective plurality of ablation electrodes in a patient body with the amplified replicas. The processor is configured to receive a return signal, including a superposition of the replicas sensed by a patch electrode attached to the patient body, and to adaptively adjust the phases and amplitudes of the replicas in response to the return signal, by controlling the control circuitry.

An electrosurgical generator is presented for controlling a surgical instrument. The electrosurgical generator includes a controller programmed to generate a first carrier wave signal and a second carrier wave signal based on an algorithm employing real-time current values of tissue at a tissue site to determine tissue impedance at a distal end of the surgical instrument, the first carrier wave signal having a first oscillating waveform and the second carrier wave signal having a second oscillating waveform, a multistage variable gain amplifier for amplifying the first and second oscillating waveforms to generate a first output signal for a first mode of operation and a second output signal for a second mode of operation, and an electrosurgical connector for transmitting the first and second output signals. The controller concurrently runs the first and second oscillating waveforms while switching between the first mode of operation and the second mode of operation.

A percutaneous catheter system for use within the human body and an ablation catheter for ablating a selected tissue region within the body of a subject. The percutaneous catheter system can include two catheters that are operatively coupled to one another by magnetic coupling through a tissue structure. The ablation catheter can include electrodes positioned within a central portion. The ablation catheter is positioned such that the central portion of a flexible shaft at least partially surrounds the selected tissue region. Each electrode of the ablation catheter can be activated independently to apply ablative energy to the selected tissue region. The ablation catheter can employ high impedance structures to change the current density at specific points. Methods of puncturing through a tissue structure using the percutaneous catheter system are disclosed. Also disclosed are methods for ablating a selected tissue region using the ablation catheter.