A surgical instrument that includes first and second jaws that are movably coupled together to move between an open and a closed position. The first jaw includes a first proximal end, a first distal tip, and a first jaw midpoint between the first proximal end and the first distal tip. The second jaw includes a second proximal end and a second distal tip. The first jaw includes a first alignment feature that is distal to the first jaw midpoint and is configured to engage a corresponding portion of the second jaw when the first and second jaws are moved to the closed position to align the first distal tip with the second distal tip.

Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.

Various aspects of a generator, ultrasonic device, and method for estimating a state of an end effector of an ultrasonic device are disclsoed. The ultrasonic device includes an electromechanical ultrasonic system defined by a predetermined resonant frequency, including an ultrasonic transducer coupled to an ultrasonic blade. A control circuit measures a complex impedance of an ultrasonic transducer, wherein the complex impedance is defined as

[00001]$Z_g(t)=\frac{V_g\left(t\right)}{I_g\left(t\right)}.$

The control circuit receivs a complex impedance measurement data point and compares the complex impedance measurement data point to a data point in a reference complex impedance characteristic pattern. The control circuit then classifies the complex impedance measurement data point based on a result of the comparison analysis and assigns a state or condition of the end effector based on the result of the comparison analysis.

Neuromodulation catheter systems with controlled irrigation capabilities and methods for using such systems are disclosed herein. One such method includes, for example, positioning an irrigated neuromodulation catheter at a treatment site within a renal blood vessel of a human patient, delivering neuromodulation energy at the treatment site, and delivering irrigation fluid to the treatment site having characteristics coordinated with the delivered energy. The characteristics can be adjusted to maintain an energy delivery element and/or tissue of the blood vessel at a constant temperature as power is increased. The method can further include monitoring at least one parameter of the tissue and/or of the energy delivery element, and adjusting the neuromodulation energy and/or the characteristics of the irrigation fluid if the at least one parameter falls outside of a treatment range of values.

A surgical system according to one or more embodiments may include: manipulators respectively supporting an endoscope and first and second surgical instruments; a remote control apparatus including a display device, a first operation handle for right hand to operate the first surgical instrument, and a second operation handle for left hand to operate the second surgical instrument; and a control apparatus. The control apparatus may display, on the display device, a graphical user interface, overlapped with the image captured by the endoscope, the graphical user interface including a first area that displays information on the first surgical instrument to be operated by the first operation handle, a second area that displays information on the second surgical instrument to be operated by the second operation handle, and a third area that displays information on the endoscope, which are arranged side by side in order from right to left.

The present invention relates to a pulse generating circuit for an electrosurgical generator, for generating a waveform suitable for causing electroporation of biological tissue. The pulse generating circuit comprises a voltage source connectable to a load via a switching element, and an open circuit coaxial transmission line connected between the switching element and the voltage source to be charged by the voltage source when the switching element is in an OFF state and to be discharged when the switching element is in an ON state. The switching element comprises a plurality of series connected avalanche transistors, and a trigger pulse generator configured to generate a trigger pulse to activate the plurality of series connected avalanche transistors. Furthermore, the impedance of the coaxial transmission line is configured to match a sum of (i) the impedance the plurality of series connected avalanche transistors, and (ii) the impedance of the load.

An electrode unit of the invention includes: an electrode including one end and another end, the other end including a free end; and an electrode supporting portion that supports the one end of the electrode. The electrode is disposed in a second plane that is different from a first plane in which the electrode supporting portion is moved to advance or withdraw when the electrode supporting portion is moved to advance or withdraw in a direction along a longitudinal axis of the electrode supporting portion, and the electrode is supported by the electrode supporting portion via a flexed portion projecting from the first plane to the second plane.

Systems, devices, and methods for electroporation ablation therapy are disclosed, with the system including a signal generator for generating pre-ablation signals and pulse waveforms for medical ablation therapy that may be coupled to an ablation device including at least one electrode for ablation pulse delivery to tissue. The signal generator may generate and delivery pre-ablation signals to subsets of electrodes of the ablation device and measure currents associated with the delivery to determine whether the currents meet one or more predetermined criteria. The signal generator may also generate and deliver voltage pulses to the ablation device in the form of a pulse waveform after determining that the currents meet the one or more predetermined criteria.

An ablation device and method for pulsed field ablation, the device comprising a catheter including an expandable basket, a set of electrodes formed on the expandable basket, and a pulse generator suitable for generating electric pulses wherein the pulse generator being in electrical connection with the set of electrodes. The expandable basket is formed of a braided mesh of filaments, wherein the filaments are made of nonconductive material, wherein at least portion of the filaments comprises a lumen, wherein the filaments further include electrodes and conductive wires. The conductive wires at least partially lead inside of the lumen of the filaments and are electrically connected to the electrodes.

A method for performing an electrosurgical procedure at a surgical site on a patient includes continually sensing electrical and physical properties proximate the surgical site that includes acquiring readings of tissue electrical impedance with respect to time at the surgical site; identifying the minima and maxima of the impedance readings with respect to time; and correlating the minima and/or the maxima of the impedance readings with hydration level and/or hydraulic conductivity in the tissue at the surgical site. The method also includes controlling the application of electrosurgical energy to the surgical site to vary energy delivery based on the step of correlating the minima and/or the maxima of the impedance readings with the hydration level/or and the hydraulic conductivity in the tissue at the surgical site. The process may be an ablation process.