A system and method for dynamic validation, registration correction for surgical navigation during medical procedures involving confirmation of registration between previously registered virtual objects, in a common coordinate frame of a surgical navigation system and an operating room, and intra-operatively acquired imaging during the medical procedure in the common coordinate frame. The method involves displaying intra-operatively acquired imaging of the surgical field, containing the real objects corresponding to the previously registered virtual objects, with the real objects being tracked by a tracking system. The method involves overlaying a virtual image containing the previously registered virtual objects onto the intra-operatively acquired imaging, from the point of view of the intra-operatively acquired imaging, and detecting any misalignment between any the previously registered virtual objects contained in the virtual image and its corresponding real object contained in the intra-operatively acquired imaging.

A segmental tracking method includes receiving first image data corresponding to a surgical site comprising at least one anatomical object, the first image data generated using a first imaging modality; receiving second image data corresponding to the surgical site, the second image data generating using a second imaging modality different than the first imaging modality; correlating a representation of the at least one anatomical object in the second image data to a representation of the at least one anatomical object in the first image data; and updating a digital model of the at least one anatomical object based on the correlation.

A system and a method for determining a relative position of an ultrasound transceiver with respect to an opening of an interventional device where the opening is within a lumen of the interventional device. Ultrasound transmissions from an ultrasound transceiver, capable of moving through at last part of the lumen and the opening are reflected off the wall or boundary of the lumen. The ultrasound transceiver may receive one or more 5 echoes of the ultrasound transmissions and generate a receive signal comprising the one or more echoes and transmit receive data comprising one or more characteristics of the echo to a data processor. The data processor is configured to identify from the receive data the one or more characteristics and determine a relative position of the ultrasound transceiver with respect to the opening based on the one or more characteristics. A transceiver may be part of 10 a retrofit device with which the interventional device may be equipped during an interventional procedure. After having determined the relative position, a location within a subject of the interventional device equipped with the retrofit device may be determined through tracking of the transceiver by an US imaging apparatus during the procedure.

A method comprises advancing a medical instrument and a catheter toward a target tissue within a patient anatomy. The instrument includes a distal sheath marker and is slidably received within the catheter. The distal sheath marker includes a channel and an identification feature. A portion of the instrument is slidably received within the channel. The method further comprises depositing the distal sheath marker at a location at or near the target. The distal sheath marker indicates a farthest advancement point of the instrument within the patient anatomy. The method further comprises: after depositing the distal sheath marker, withdrawing the instrument away from the target; determining an orientation of the distal sheath marker based on the identification feature; and, after withdrawing the instrument, using the location and orientation of the deposited distal sheath marker to determine a trajectory of a distal end of the instrument at or near the target.

Microresonator structures including a top polymer film layer, a bottom polymer film layer, and a smart hydrogel structure sandwiched between the polymer film layers. An ultrasound resonator cavity having a resonance frequency is defined between the top and bottom polymer layers, and the smart hydrogel structure is configured to provide a change in height to the ultrasound resonator cavity due to volumetric expansion or contraction of the smart hydrogel structure, in response to interaction of the smart hydrogel structure with one or more predefined analytes in an in vivo or other environment. Related methods of use for determining the presence or concentration of a given target analyte, as well as methods of fabricating such microresonator structures are also described.

A vascular occlusion treatment system includes an ultrasound imaging system having an imaging control circuit communicatively coupled to an ultrasound imaging probe and to a display screen, and an ultrasonic vibration system having an ultrasonic generator operatively coupled to a medical ultrasonic object, such as an ultrasonic catheter. The ultrasonic catheter has a corewire with a distal tip. The ultrasonic generator has a generator control circuit that alternatingly switches between an ultrasonic work frequency and a tracking frequency. The generator control circuit sends a notification to the imaging control circuit when the generator control circuit has switched from the ultrasonic work frequency to the tracking frequency. The imaging control circuit responds by initiating a search in an ultrasound imaging space to locate the distal tip that is vibrating at the tracking frequency, and indicating a location of the distal tip in the ultrasound image displayed on the display screen.

A system (200) performs a medical procedure in a region of interest of a patient. The system includes an interventional medical device (214) insertable into the region of interest, and a sensor (215) attached to a portion of the interventional device, the sensor being configured to convert an ultrasonic wave from an ultrasound imaging probe (211) to a corresponding electrical radio frequency (RF) signal. The corresponding RF signal is received by a wireless receiver (209) outside the region of interest, enabling determination of a location of the sensor within the region of interest.

Ultrasound imaging is a non-invasive, non-radioactive, and low cost technology for diagnosis and identification of implantable medical devices in real time. Developing new ultrasound activated coatings is important to broaden the utility of in vivo marking by ultrasound imaging. Ultrasound responsive macro-phase segregated micro-composite thin films were developed to be coated on medical devices composed of multiple materials and with multiple shapes and varying surface area. The macro-phase segregated in films having silica micro-shells in polycyanoacrylate produces strong color Doppler signals with the use of a standard clinical ultrasound transducer. Electron microscopy showed a macro-phase separation during slow curing of the cyanoacrylate adhesive, as air-filled silica micro-shells were driven to the surface of the film. The air sealed in the hollow space of the silica shells acted as an ultrasound contrast agent and echo decorrelation of air exposed to ultrasound waves produces color Doppler signals.

A method for performing a surgical procedure includes planning a resection of a bone of a patient. A volume of the bone is removed according to the planned resection using a surgical tool. As the bone is removed, data corresponding to a shape and volume of the removed bone is tracked with a computer system operatively coupled to the surgical tool. A prosthesis is implanted onto the bone of the patient based on the tracked data corresponding to the shape of the removed bone.

In general, devices, systems, and methods for fiducial identification and tracking are provided.