During both invasive and non-invasive treatments and therapies, health professionals need to accurately locate areas of interest. Inaccuracies may mean that not all the area is treated, or the treatment is incomplete. Electro-magnetic and RFID (Radio-Frequency Identification) markers have been developed, but these are bulky and prone to failure. For example, any inaccuracy may result in an incomplete resection or removal of the lesion, requiring additional treatments.

A magnetic field probe 100, 101 is provided for determining an angular disposition 180, 190 of an implantable magnetic marker 200, the probe comprising: a first magnetic sensor 110 close to the distal end 160, and a second magnetic sensor 120, closer to a proximal end 165, configured to determine two or more magnetic field vectors of the marker 200; the probe being further configured: to define two or more marker detection zones 170, 171, 172, 173, 174, extending from the distal end 160; to determine the angular disposition 180, 190 to the implantable marker 200; and to determine whether the angular disposition 180, 190 substantially coincides with one of the two or more marker detection zones 170, 171, 172, 173, 174, thereby determining that the marker falls within the one marker detection zones.

By defining two or more marker detection zones, and configuring the probe to determine whether the magnetic marker appears to be within the one marker detection zone, a simplified and intuitive decision algorithm is provided for indicating the disposition of the marker relative to the probe.

Disclosed herein is a position detection marker that includes a magnetic field source that generates magnetism, an MRI marker that can be detected by a magnetic resonance imaging method, and a holding part that fixes a relative positional relation between the magnetic field source and the MRI marker.

Provided herein are methods of analyzing tissue using a magnetic resonance imaging (MRI) compatible tissue analysis device that includes radio¬frequency (RF) tracking and imaging elements. Related kits, systems, and computer program products are also provided.

A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.

Provided herein are systems, devices, assemblies, and methods for generating exciter signals, for example, to activate a remotely located tag. The systems, devices, assemblies, and methods find use in a variety of application including medical applications for the locating of a tag in a subject.

The application describes embodiments including, e.g., a measurement device comprising: a casing, a first magnet arranged within the casing such that it is rotatable out of an equilibrium orientation responsive to an external magnetic torque acting on the first magnet, a second magnet to provide a restoring torque to force the first magnet back into the equilibrium orientation responsive to an external magnetic torque rotating the first magnet out of the equilibrium orientation, allowing for a rotational oscillation of the first magnet, which is excited by the external magnetic torque, with a resonant frequency, and a temperature sensitive magnetic material to modify the resonant frequency.

A method for detecting a magnetic marker comprises generating a driving magnetic field comprising first and second frequencies and detecting a response magnetic field comprising first and second response components. The magnetic marker provides a non-linear response to the driving signal. A primary portion of the response components is generated by the magnetic marker, and secondary portion of the response components is generated by a secondary magnetic source. The method comprises determining a driving factor representing a ratio of the frequencies in the driving signal; determining a correction factor corresponding to the secondary ortion of the second response component, based on the first response component and the driving factor; determining a detection signal corresponding to the primary portion of the second response component, based on the second response component and the determined correction factor; and generating an output signal based on a strength of the detection signal.

The present invention describes method directed to magnetic resonance (MR) imaging simulation, said method comprising—creating an empty 3D slice corresponding to a prescribed slice;—placing the empty 3D slice on the transversal XY plane of an image of an anatomical model;—calculating steps of rotation and translation that if applied would bring a volume-of-interest on the transversal XY plane;—calculating steps for undoing the rotation and translation performed;—applying the steps for undoing the rotation and translation performed on the empty 3D slice so as to bring it at the position of the prescribed slice in 3D space; and—calculating interpolated values of properties of the anatomical model at points of the empty 3D slice which have been placed at the position of the prescribed slice in 3D space, preferably wherein the method also involves a subsequent step of one-to-one matching of the calculated interpolated values with the corresponding points of the empty 3D slice on the transversal XY plane before calculating the steps of rotation and translation that, if applied, would bring the volume-of-interest on the XY plane, centered at 0, 0, 0.

This document relates to the apparatus and methods used in the minimally invasive creation of arteriovenous fistula (AVF). In particular, the invention relates to the creation of an AVF using catheters and an alignment methodology that is based upon detection of asymmetric electric fields. The invention finds particular application in vascular access (VA) in the hemodialysis (HD) population.

A marker coil includes a flexible substrate, a coil formed on the substrate by wiring, and a substrate holding part that is capable of being attached to a testee. A convex shape is formed in one of the substrate and the substrate holding part, and an engaging part for engaging the convex shape is formed in the other one of the substrate and the substrate holding part.