A biosensor includes a PPG circuit that emits light directed at living tissue at a plurality of wavelengths. A first and second spectral response of light reflected from the tissue is obtained around a first wavelength and a second wavelength. Using absorption coefficients for substances at the plurality of wavelengths, concentration levels of a plurality of substances such as Nitric Oxide may then be determined from the spectral responses.

Optical geometry calibration devices, systems, and related methods for x-ray imaging are disclosed. An optical-based geometry calibration device is configured to interface with a two-dimensional (2D) imaging device to perform three-dimensional (3D) imaging. The optical-based geometry calibration device includes one or more optical cameras fixed to either an x-ray source or an x-ray detector, one or more markers fixed to the x-ray detector or the x-ray source, with each of the one or more optical cameras being configured to capture at least one photographic image of one or more corresponding optical markers when each x-ray image of the object is captured, and an image processing system configured to compute positions of the x-ray source relative to the x-ray detector for each 2D projection image based on the at least one photographic image of the one or more markers

Disclosed is a bioimpedance measurement system: A stabilized high frequency current generator is connected to PadSet electrodes via a Patient Cable. Electrodes are connected to an adaptive circuit that conditions the resulting voltage signal and converts it to digital form. Firmware performs signal acquisition and relays data to the device.

A processing apparatus, comprises: a first acquirer configured to acquire a first specific information distribution of an object based on acoustic waves propagating from the object onto which light is irradiated; a second acquirer configured to acquire a characteristic value of the first specific information distribution of the object; a third acquirer configured to acquire information indicating a correspondence between an optical coefficient and the characteristic value of the first specific information distribution; and a fourth acquirer configured to acquire the optical coefficient of the object using the characteristic value of the first specific information distribution of the object and the information indicating the correspondence.

A method and a system for measuring inspiratory/expiratory air flow rate from inhalation/expiration near a microphone of an electronic device by a user. An inhaler is selected by the user among a plurality of possible inhalers, and the user is prompted to perform an inhalation/expiration close to a microphone of the computing device. Sound is measured during inhalation/expiration and sound data derived therefrom. There is determined the inspiratory/expiratory air flow rate by comparing the collected sound data with a flow rate data set used by the industrially calibrated device and stored in an inhaler-appropriate flow-rate database, and if the inspiratory/expiratory air flow rate is within a predetermined range for the selected inhaler, thereby determining whether the selected inhaler is one of the appropriate inhalers for the inspiratory/expiratory flow measured by comparing the determined inspiratory/expiratory air flow rate with a range of inspiratory/expiratory air flow rates corresponding to the selected inhaler.

Indirect, oscillometric, digital blood pressure monitoring systems and methods enabling self-calibration to obtain absolute blood pressure values using algorithmic analysis of arterial pressure pulses to establish an oscillometric profile and compensate for intervening effects on digital arterial pressure. Proper algorithmic analysis is dependent upon proper positioning and maintained engagement of a digital cuff on the digit of a user and subsequent hydraulic coupling of the cuff to the arteries within the digit.

A module for an oscillometry system of the type having an oscillatory flow source, the module comprises an enclosure adapted to be releasably connected to a core assembly of the oscillometry system. The enclosure defines a breathing flow pathway adapted to be in fluid communication with the oscillatory flow source. A user port is at a first end of the breathing flow pathway configured for receiving a breath of a user. A calibration file specific to the module is programmed as a function of the breathing flow pathway and configured for being used by the oscillometry system to assess breathing parameters for the user.

A device includes an optical circuit that obtains a first signal at a first wavelength using light reflected from skin tissue of a patient, wherein the first wavelength has a high absorption coefficient for nitric oxide (NO) in blood flow and a second PPG signal at a second wavelength using light reflected from skin tissue of the patient, wherein the second wavelength has a low absorption coefficient for NO in blood flow. A measurement of a level of NO in blood flow is determined using the first PPG signal and the second PPG signal. A health condition is determined using the measurement of the level of NO, such as hyperglycemia or hypoglycemia.

This invention generally relates to methods useful for measuring heart rate, respiration conditions, and oxygen saturation and a wearable device that incorporate those methods with a computerized system supporting data collection, analysis, readout and sharing. Particularly this present invention relates to a wearable device, such as a wristwatch or ring, for real time measuring heart rate, respiration conditions, and oxygen saturation.

Methods, devices, systems, and computer program products are provided to improve sensitivity calibration of an in vivo analyte sensor and usability of an associated analyte monitoring system. In certain embodiments, methods are provided that improve the user experience of using an analyte monitoring system. Certain embodiments of the present disclosure include features that reduce the amount of calibration or re-calibration performed by the analyte monitoring system. More specifically methods of using a suspect calibration attempt to avoid having to recalibrate by adjusting the calibration or mitigating effects of sensor signal attenuation that caused the calibration attempt to be suspect are provided. Additional features are disclosed.