The present disclosure relates to a device, method and system for calculating, estimating, or monitoring the blood pressure of a subject based on physiological features and personalized models. At least one processor, when executing instructions, may perform one or more of the following operations. A first signal representing a pulse wave relating to heart activity of a subject may be received. A plurality of second signals representing time-varying information on a pulse wave of the subject may be received. A personalized model for the subject may be designated. Effective physiological features of the subject based on the plurality of second signals may be determined. A blood pressure of the subject based on the effective physiological features and the designated model for the subject may be calculated.

A bio-processor, a bio-signal detecting system, and an operation method of the bio-processor are provided. The bio-processor includes a bioelectrical impedance sensor and a digital signal processor. The bioelectrical impedance sensor measures bioelectrical impedance during a sensing time including a portion of a settling time. The digital signal processor estimates a settled bioelectrical impedance value based on changes in the measured bioelectrical impedance. The digital signal processor generates bio-data based on the settled bioelectrical impedance value. The bio-processor reduces a time when a bio-signal is measured and ensures accuracy of the settled bioelectrical impedance value.

Hip joint navigation systems and methods are provided. In some embodiments, the systems and methods described herein determine a table reference plane that approximates the Anterior Pelvic Plane. In some embodiments, the systems and methods described herein measure a pre-operative and post-operative point. In some embodiments, the comparison of the pre-operative and post-operative point corresponds to changes in leg length and joint offset. In some embodiments, the systems and methods described herein determine an Adjusted Plane. In some embodiments, the Adjusted Plane adjusts for tilt by rotating the Anterior Pelvic Plane about the inter-ASIS line. In some embodiments, the Adjusted Plane improves correlation between navigated cup angles and post-operative images.

A device for measuring a force exerted on a body comprises a flexible rod having a proximal end and a distal end intended to come into contact with the body and to apply a force tending to deform the body near a point of contact. The measuring device also comprises an image capturing device, which is rigidly attached to the proximal end and oriented toward the distal end of the flexible rod, for providing at least one depth map of the body near the distal end of the flexible rod. The device may be used to perform a method of measuring the force exerted on the body and a method of characterizing the rigidity of a body

Medical devices and related systems and methods are provided. A method of calibrating an instance of a sensing element involves obtaining fabrication process measurement data from a substrate having the instance of the sensing element fabricated thereon, obtaining a calibration model associated with the sensing element, determining calibration data associated with the instance of the sensing element for converting the electrical signals into a calibrated measurement parameter based on the fabrication process measurement data using the calibration model, and storing the calibration data in a data storage element associated with the instance of the sensing element.

Systems and methods for improving production and/or calibration of biosensors are disclosed herein. The biosensors can be used for personal biomonitoring and providing personalized healthcare assessments. The manufacturing method can include gathering production data throughout production of the biosensors and using the production data to predict performance metrics for each biosensor. The predicted performance metrics can be generated using one or more models correlating the production data to the performance metrics. The predicted performance metrics can then be used by a biomonitoring system to adjust operating parameters of the biosensor before a user relies on the healthcare assessments from the biomonitoring system.

The present invention provides a PHHM for the measurement of a subject's BP and, optionally, one or more other vital signs, comprising a housing located on a PHHCD or a hand-held component of a computing system; a blood flow occlusion means located in the housing such that, when the housing is located on the PHHCD or the hand-held component, an open surface of the blood flow occlusion means is available to be pressed against a body part of the subject or to have a body part of the subject pressed against it; a pressure sensor adapted to provide an electrical signal indicative of the pressure applied to or by the open surface; a means for detecting the flow of blood in the body part of the subject when pressure is applied to or by the open surface; and means for receiving electrical signals from the pressure sensor and the blood flow detecting means and for transmitting electrical signals indicative of the pressure and blood flow to the processor of the PHHCD or the computing system, wherein the processor of the PHHCD or computing system is adapted to process signals acquired by the pressure sensor and the blood flow detecting means to provide at least a measurement of the BP of a subject, the processor is further adapted to carry out a process to measure a DBP value and a SBP value, the DBP and the SBP values are estimated in such a way that the difference between the measured optical signals and those that would be generated by the estimation of the DBP and SBP values is minimized or the DBP and the SBP values are estimated in such a way that the difference between the measured incremental pressure signals and those that would be generated by the estimation of the DBP and SBP values is minimized. The present invention also provides alternative PHHMs and SADs for use in such PHMS.

Certain exemplary embodiments can provide an apparatus wearable by a user. The apparatus can comprise a biometric sensor constructed to generate signals based upon measurements of the user. The apparatus can comprise a processor constructed to determine a significant detrimental change in the user via an algorithm based upon the signals.

Techniques for sensor calibration involve determining a generative model using sensor measurements from different instances of a first glucose sensor together with corresponding reference glucose values. The generative model is configured to generate a simulated measurement representing a predicted output of the first glucose sensor under specific operating conditions. A set of simulated measurements is generated using operating conditions observed with respect to a second glucose sensor as inputs to the generative model. The second glucose sensor is a sensor of a different design. The operating conditions observed with respect to the second glucose sensor include reference glucose values obtained in connection with measurements made using the second glucose sensor. The simulated measurements are then used to determine an estimation model for the first glucose sensor. The estimation model is configured to estimate glucose level given one or more sensor measurements from the first glucose sensor.

Various methods and systems are provided for calibrating a camera-based feature detection system for an x-ray system having a support surface, and a gantry operably connected to the support surface and a light source disposed on the gantry, where the gantry defines a system referential. The x-ray system includes a camera spaced from the gantry and operably connected to a calibration system, the camera defining a camera referential within which the support surface and gantry are positioned. The calibration system registers the camera referential to the system referential by operating the light source to position an indication on the support surface and by obtaining a number of camera images of the indication on the support surface and corresponding indication location in the system referential.