Systems and methods for an improved dosimeter for measuring dosage for photodynamic therapy treatment are provided. An example systems includes a dosimeter comprising a variable optical filter system configured to receive a second light, the second light comprising luminescence produced by singlet oxygen and one or more background signal and selectively transmit the luminescence and the one or more background signals as a third light, the variable optical filter system comprises a plurality of optical bandpass filters that are switchable to selectively transmit the luminescence and the one or more background signals. The dosimeter also includes a photoreceiver configured to receive the third light and configured to generate electrical output signals corresponding to the luminescence and the one or more background signals, the electrical output signals being indicative of an amount of the singlet oxygen produced based on activating the photosensitizer.

A calibration method of an optical coherence tomography (OCT) device and a camera using the same target includes irradiating a shape measurement light to a calibration target, obtaining a surface shape image thereof by detecting light reflected by a surface of the calibration target using a shape measurement camera, and calibrating the surface shape image according to an actual shape of the calibration target; obtaining surface and internal three-dimensional images of the calibration target by scanning with a layer measurement light using the OCT measurement unit, extracting a surface shape image of the calibration target from the three-dimensional images, and calibrating the surface shape image according to the actual surface shape of the calibration target; and matching a calibration image obtained by the shape measurement camera and a surface calibration image obtained by the OCT measurement unit to be displayed at the same spatial coordinates.

According to an aspect there is provided a method of determining a calibration parameter for a first blood pressure, BP, measurement device, the method comprising obtaining a first physiological characteristic measurement of a subject using the first BP measurement device, wherein the first BP measurement device is for obtaining physiological characteristic measurements of a physiological characteristic of the subject and for determining a BP measurement of the subject from the physiological characteristic measurements using the calibration parameter, wherein the first physiological characteristic measurement is obtained when a torso of the subject is in a first posture; obtaining a second physiological characteristic measurement of the subject using the first BP measurement device, wherein the second physiological characteristic measurement is obtained when the torso of the subject is in a second, different, posture; determining the change in the posture of the torso from the first posture to the second posture; estimating a change in BP of the subject or a change in the physiological characteristic of the subject from the determined change in the posture of the torso; and determining the calibration parameter for determining BP measurements from physiological characteristic measurements obtained by the first BP measurement device from an analysis of the first physiological characteristic measurement, the second physiological characteristic measurement and the estimated change.

The invention relates to a medical device (12) comprising an electrical measurement circuit (16), in which are connected at least two variable-impedance sensors (22), the impedance of which varies according to a detected physical quantity, an electrical power source (18) for supplying power to the electrical measurement circuit (16), an antenna (18) for emitting an electromagnetic field according to the impedance of the electrical measurement circuit (16), each of the sensors (22) being associated with a switch (24) for interrupting the current supply of the sensor (22) in said measurement circuit (16), the medical device (12) additionally comprising a system (26) for controlling the switches (24) in order to successively control the opening or the closing of the switches (24), according to determined configurations. The medical device (12) may in particular be applied to the human body or implanted within the human body.

A magnetometer-based metal detection device and methods of use are described. The device includes a proximal portion, a central body and a distal portion, and at least one magnetometer positioned within or on the distal portion. The at least one magnetometer includes at least one sensor capable of sensing a magnetic field in three orthogonal axes. Also described is a method of calibrating the device to achieve rotational invariance, and a method of determining a directionality or directional line along which a target metal object lies.

Aspects of the present disclosure include a sensor configured to store in memory indications of sensor use information and formulas or indications of formulas for determining the useful life of a sensor from the indications of sensor use information. A monitor connected to the sensor monitors sensor use and stores indications of the use on sensor memory. The monitor and/or sensor compute the useful life of the sensor from the indications of use and the formulas. When the useful life of the sensor is reached, an indication is given to replace the sensor.

Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user. The in vivo analyte sensor is coupled to an electronics unit holding a memory with instruction to cause processing circuitry to initiate a predetermined time period that is longer than a predetermined life of the sensor, during the predetermined time period, convert signals from the sensor related to glucose to respective corresponding glucose levels, without relying on any post-manufacture independent analyte measurements from a reference device, and at the expiration of the predetermined time period, disable, deactivate, or cease use of one or more feature.

The disclosed techniques include obtaining a first signal generated by an electrochemical glucose sensor and a second signal generated by an optical glucose sensor, and obtaining a glucose value indicative of a user's blood glucose level, where the glucose value and the second signal are obtained at different times. The disclosed techniques further cause calculating a mapped value for the second signal based on the first signal, and calibrating the mapped value of the second signal based on the glucose value.

A temperature measurement system for measuring a temperature of a measured surface includes: 1) a first temperature sensor; and 2) a reference surface including a second temperature sensor integrated therein. The first temperature sensor includes a field of view simultaneously covering both at least a portion of the measured surface and at least a portion of the reference surface, thus is configured for simultaneously taking a first measurement of both the portion of the measured surface and the portion of the reference surface. The first measurement of the reference surface taken by the first temperature sensor is compared to a second measurement taken by the second temperature sensor for use in calibrating the first temperature sensor.

The present application discloses a method of adjusting a parameter, the parameter being used to derive a physiological characteristic of an individual from an image of the user, the method comprising the steps of: obtaining the parameter for the individual; obtaining a corresponding parameter for a plurality of other individuals within a cohort of the individual; comparing the parameter for the individual with a statistically significant parameter for the plurality of other individuals; and adjusting the parameter for the individual in accordance with the difference between the parameter for the individual and the statistically significant parameter for the plurality of other individuals.