The invention relates to a detection apparatus (12) for detecting photons. The detection apparatus comprises a pile-up determining unit (15) for determining whether detection signal pulses being indicative of detected photons are caused by a pile-up event or by a non-pile-up event, wherein a detection values generating unit (16) generates detection values depending on the detection signal pulses and depending on the determination whether the respective detection signal pulse is caused by a pile-up event or by a non-pile-up event. In particular, the detection values generating unit can be adapted to reject the detection signal pulses caused by pile-up events while generating the detection values. This allows for an improved quality of the generated detection values.

Intraocular pressure sensing devices and methods of use. The intraocular pressure sensing devices may include one or more calibration sensors that are adapted to sense fibrotic growth over the implant post-implantation. Methods can take into account the amount of fibrosis over the implant, and its effect on IOP, when calculating the subject's IOP. Additionally, methods herein can calculate IOP while factoring in blink-induced variation in IOP.

A perspiration sensing system includes a sensor patch and a smart device. The sensor patch includes one or more perspiration sensing portions. The one or more perspiration sensing portions include an inlet having a predefined size to receive perspiration from a predefined number of sweat glands and an outlet for reducing back pressure. At least one perspiration sensing portion includes a channel having a colorimetric sensing material that changes color when exposed to perspiration. At least one perspiration sensing portion includes a colorimetric assay in a substrate that changes color when exposed to biochemical components of perspiration. The system further includes a smart device having a camera that can take a picture of the sensor patch and determine the volume, rate of perspiration, and/or biochemical components of the perspiration from the one or more perspiration sensing portions.

An optical measuring device includes: a light source unit; a measurement probe including a fiber bundle, an illumination fiber that illuminates a living tissue with a illumination light, and a plurality of light-receiving fibers that receives return light of the illumination light reflected and/or scattered at the living tissue; a detection unit that receives the return light of the illumination light detected by the plurality of respective light-receiving fibers, and performs photoelectric conversion to detect respective signal intensities; and an association unit that associates the respective signal intensities detected by the detection unit with distances from the illumination fiber to the respective light-receiving fibers on an end face of a distal end portion of the measurement probe, when light having an intensity gradient around the illumination fiber is projected to the end face of the distal end portion of the measurement probe.

A system for monitoring the respiratory activity of a subject, which comprises one or more signal generating elements being kinematic or light emitting elements, applied to the thorax of a subject, for generating signals that are indicative of movement of the thorax of the subject; a receiver for receiving the generated signals during breathing motion of the subject; and one or more computing devices in data communication with the receiver, for analyzing the breathing motion. The more computing device is operable to calculate, in response to the received generated signals, the magnitude of a maximum displacement in 3D space of the one or more signal generating elements during a cycle of the breathing motion; and to calculate the magnitude of a current displacement in 3D space of the one or more signal generating elements during the breathing motion with respect to a reference tidal volume associated with the maximum displacement in 3D space.

A system and method for monitoring the health of an animal using multiple sensors is described. The wearable device may include one or more sensors whose resultant signal levels may be analyzed in the wearable device or uploaded to a data management server for additional analysis. One or more embodiments include variations of the UWB system to accommodate differences in animals, such as scheduling or attempting transmissions between the wearable device and the data management server in such a way as to increase the likelihood of a successful transmission.

A system and methods for monitoring and controlling a mental state of a subject are provided. In some aspects, a method includes receiving physiological and behavioral data acquired using the plurality of sensors while the subject is performing a task, and applying, using the data, a state-space framework to determine a plurality of decoder parameters correlating brain activity and behavior with a mental state of the subject. The method also includes identifying the mental state of the subject using the decoder parameters, and generating a report indicating the mental state of the subject. In some aspects, the method further includes generating, based on the identified mental state, a brain stimulation to treat a brain condition of the subject.

Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate sensor information to one or more display devices. Establishment of communication between devices can involve using a unique identifier associated with the sensor electronics module to authenticate communication. Times tracked at the sensor electronics module and the display module can be at different resolutions, and the different resolutions can be translated to facilitate communication. In addition, the frequency of establishing communication channels between the sensor electronics module and the display devices can vary depending upon whether reference calibration information is being updated.

A patient support apparatus includes a load frame, a support frame, and a plurality of load cells supporting the load frame on the support frame such that a load supported by the load frame is supported by the load cells, each load cell configured to produce a signal indicative of a load weight bearing upon that load cell. The load cells are calibrated after installation.