Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

A Transcutaneous Electrical Nerve Stimulation, TENS, device has a pair of electrodes for attachment to the skin of a user. It is determined that at least one of the electrodes is peeling, by applying constant voltage pulses to the pair of electrodes; detecting a peak current at the start of the pulse, and detecting a plateau current at the end of the pulse; comparing peak currents from a plurality of pulses; comparing plateau pulses from the plurality of pulses; and determining that at least one of the electrodes is peeling if the peak currents from the plurality of pulses decline over time and if the plateau pulses from the plurality of pulses decline over time.

A failure determination apparatus of an ultrasound diagnosis apparatus includes a determination unit configured to, using a trained model trained on data generated in a first ultrasound diagnosis apparatus in a failed state as supervised data, determine whether a second ultrasound diagnosis apparatus is in a failed state based on data generated in the second ultrasound diagnosis apparatus, and a notification unit configured to notify an operator of a result of determination by the determination unit.

A test fixture (20) for testing continuity in at least one electrode of a neuromodulation device. The test fixture may comprise a substrate (22), at least one electrically conductive pad (24a) disposed on the substrate for reducing pressure applied to the at least one electrode when the electrically conductive pad makes contact with an exposed surface of the electrode, and a wire (26a) extending from the at least one electrically conductive pad. The pad may be formed of a non-abrasive material, such as conductive foam or smooth metal. The substrate may be a probe formed with a number of slots for holding pads and routing wires, a mandrel with openings for holding pads and routing wires, and a flexible circuit with exposed smooth metal surfaces. The test fixture may be suitable for testing cuff-like and paddle-like devices.

A medical sensor includes an application-specific integrated circuit (ASIC), medical hardware, and a communication module. The ASIC is communicatively coupled to the medical hardware and communication module. The ASIC is configured to receive measurement signals from the medical hardware and provide the measurement signals to the communication module. The communication module is configured to process the measurement signal into measurement results and transmit the measurement results to a remove device. The communication module includes an application layer for processing the measurement signals and a link layer for transmitting the measurement results. The ASIC is configured to detect that a voltage supplied to the ASIC is below a threshold level and determine an amount of time that the voltage has been below the threshold level. The ASIC is further configured to respond to the voltage supplied to the ASIC being below a threshold level based on the determined amount of time.

Apparatus, methods, and systems for detecting alcohol concentrations of an individual, such as an in vivo alcohol concentrations of an individual. The system can include an analyte sensor and a reader. The reader can receive a signal from the analyte sensor. The reader can determine blood alcohol concentration, in part, based on the received signal from the analyte sensor. The reader can also detect an adverse condition of the analyte sensor, and/or output an indication based on the detected adverse condition.

A method of determining signal quality in a patient monitoring device includes acquiring one or more signals using the patient monitoring device. One or more signal quality metrics are determined based on the one or more acquired signals. A noise condition is detected based on the one or more signal quality metrics, and a determination is made whether the noise condition should be classified as intermittent or persistent. One or more actions are taken based on the classification of detected noise as intermittent or persistent.

Methods and devices and systems include generating analyte data based on signals from an analyte sensor transcutaneously positioned in contact with interstitial fluid under a skin layer of a user and to generate signals corresponding to an analyte level of a target analyte. The analyte data corresponds to the analyte level of the target analyte over a wear period. Methods include storing the analyte data over the wear period. Methods include determining one or more indications based on the analyte data. Methods include determining a reimbursement insurance code based at least in part on stored sensor information associated with the analyte sensor. Methods include communicating at least a portion of the analyte data and the reimbursement insurance code to an electronic record associated with the user and stored by a remote electronic medical record system. Methods include providing the one or more indications on a user interface unit.

A microphone assembly includes an acoustic transducer configured to generate an analog signal in response to pressure changes sensed by the acoustic transducer. The analog signal includes frequency components below a threshold frequency. The microphone assembly also includes an integrated circuit electrically coupled to the acoustic transducer and configured to determine a characteristic of frequency components below the threshold frequency, determine whether the characteristic of the frequency components corresponds to a fall event, and generate an output signal in response to a determination that the characteristic of the frequency components corresponds to the fall event. The microphone assembly also includes a housing having an external device interface with electrical contacts. The acoustic transducer and the integrated circuit are disposed within the housing. The integrated circuit is electrically coupled to contacts of the external device interface.

A fault detection device includes at least one electricity generating unit, to impress a signal on a first useful signal path; at least one first comparison unit, to determine if the signal of the first useful signal path lies within a measuring range; and at least one first interference signal path, designed as a current measurement path, for current-detecting measurement of a first interference signal. A signal path defect analysis unit, is included to detect a signal path defect, upon the impressed signal not being measured on the at least one first interference signal path and upon the checked signal of the comparison unit being determined to lie within the measuring range. Furthermore, corresponding methods are for the detection of signal path defects in a voltage measuring system for measuring bioelectric signals are defined.