A wireless near-infrared spectrometry sensor includes a light source for emitting near-infrared energy into tissue and a light receiver for receiving the near-infrared energy after it exits the tissue. The sensor may include a portable energy source for supplying energy to the light source. A processing module may control the light source and process readings in connection with the light source. A wireless transceiver may be coupled to the processing module for at least one of transmitting and receiving information, wherein the light source emits near-infrared energy at predetermined intervals in order to conserve energy in the portable energy source. The portable energy source may include at least one of a battery, a capacitor, a thermoelectric generator, a kinetic energy transducer, electricity derived from RF energy, and any combination thereof. The sensor may further include a substrate for support and which may be part of a sterile bandage.

A measurement system is proposed for building a magnetic field map of an object. The system comprising: a light source arrangement for emitting a plurality of light beams, a respective light beam being configured to travel in the measurement system along a respective optical path; a plurality of measurement sensors sharing a first magneto-optical layer comprising at least a first Faraday material layer and a first light reflector for reflecting the plurality of light beams travelled through the first Faraday material layer in a first direction back to the first Faraday material layer in a second, opposite direction; one or more reference sensors; and one or more light detectors.

An electronic device including optical sensing with a concentric architecture and methods for operation thereof is disclosed. The concentric architecture can include light detector(s) arranged in a concentric manner around light emitter(s). In some examples, at least one light emitter can be located in the center of the device, and each light detector can be located the same separation distance from the light emitter. Each light detector can be arranged such that the separation distance from the centrally located light emitter can be greater than the separation distance from another light emitter. Examples of the disclosure further include a selective transparent layer overlaying the light detector(s). The selective transparent layer can include section(s) transparent to a first wavelength range and non-transparent to a second wavelength ranges. In some examples, the selective transparent layer can further include section(s) transparent to the second wavelength range.

An optical filter device, system, and method for improved optical rejection of out-of-band wavelengths is disclosed. For example, an analyte detection system is provided that includes an excitation light source for illuminating an implantable sensor and an optical detector for collecting emission light from the implantable sensor. Further, the analyte detection system includes an optical filter device arranged between the implantable sensor and the optical detector, wherein the optical filter device provides high optical rejection of out-of-band wavelengths of the emission light.

The invention relates to an apparatus for determining a property of a tissue, particularly cancer of cervical tissue. A light providing unit (7, 8, 9) provides light for illuminating the tissue (6) and a light detection unit (10) detects light from the tissue, wherein a first signal being indicative of light (11) having been influenced by an epithelium region (R1), a second signal being indicative of light (12) having been influenced by a boundary region (R2) and a third signal being indicative of light (13) having been influenced by a stroma region (R3) are generated, and wherein a tissue property is determined based on the first, second and third signals. This allows for an determination of a tissue property, which is based on a combination of optical properties measured in the three different regions, resulting in an improved determination of the tissue property, in particular in improved cancer detection.

Robust estimation of a characteristic of a user's physiological signals can be achieved by filtering or classifying samples. Rather than estimating the characteristic of the user's physiological signals based on each sample at a first wavelength and a second wavelength, a robust system and method can, in some examples, estimate the characteristic using samples at the first wavelength and the second wavelength that meet one or more criteria and filter out samples that fail to meet the one or more criteria. In some examples, the system and method can weight samples based on the one or more criteria, and estimate the characteristic using the weighted samples. Samples failing to meet the one or more criteria can be given less weight or no weight in the estimation. The one or more criteria can include a criterion based on at least the physiological signal at a third wavelength.

A sensor for evaluating tissue of a subject is provided. The sensor includes a flexible spine disposable on the subject, a flexible member that includes first and second flexible member portions accommodated within the flexible spine, a light source, a detector and a rigid member. The light source is attached to the first flexible member portion and is configured to emit light toward the tissue. The detector is attached to the second flexible member portion and is configured to receive the light having reflected off the tissue. The rigid member is coupled with the first and second flexible member portions. In response to a curvature of the flexible spine, the rigid member moves the first and second flexible member portions along the flexible spine to adjust a distance between the light source and the detector.

Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM).

An in-ear optical sensor device sits deep within the ear canal of a subject such that is in the cartilaginous region and/or the bony region of the ear canal where effects from temporomandibular joint activity or other movement, and external light, are limited. The device has a lateral housing and a medial articulating head joined at an articulation joint so that the medial articulating head may be angled relative to the lateral housing to help the device fit within tortuous ear canals. The device also includes a seal configured to conform to the shape of the ear canal to physically support the device to further limit movement and block environmental light. An audio receiver is also included in the device.

The present disclosure generally relates to wearable devices and methods for measuring a photoplethysmographic (PPG) signal. The wearable devices and methods described herein are capable of obtaining PPG signals by employing a PPG sensor array configured to receive light at angles associated with a high perfusion index. Viewing components may be coupled to the PPG sensor array to effect transmission of light at these preferential angles.