Embodiments provide for intracranial delivery of a medicinal solution to the brain. A system includes a bun hole stopple for insertion in a cranial bun hole, a catheter, a connecting member, a connector tube, and a pump. The catheter is advanced through an opening in the stopple to a tissue site in the brain. A proximal portion of the catheter is fixed to an outer groove in the stopple to minimize movement of the catheter in the brain. The catheter, connecting member, connector tube, and pump are fluidically coupled together to create a flow path between the pump and a distal end of the catheter for infusion of the medicinal solution to the tissue site in the brain.

This specification generally relates to cranial prosthetics and their use in therapy. More specifically the specification relates to a cranial prosthetic, which comprises a perforated plate, wherein the perforations comprise a plurality of holes substantially equidistant from a central point. One such cranial prosthetic comprises a curved perforated plate, wherein the perforations comprise four holes substantially equidistant from a central point. The plate also comprises an additional hole at the central point, detachable screw/suture fixing tabs for attaching the cranial prosthetic to the cranium via screws/sutures, detachable securing means consisting of flaps that secure the electrode when closed, and indentations in the form of channels suitable for recessing extension leads with at least one exit point, which connect individual electrodes to the main lead. Removable protective caps may be placed over the detachable securing means when closed.

Provided herein are cranial implant devices that include a cranial implant housing configured for subgaleal scalp implantation within, beneath, and/or over at least one cranial opening of a subject. The cranial implant housing comprises a substantially anatomically-compatible shape and is fabricated from one or more sonolucent materials that permit transmission of mechanical waves through the sonolucent materials when the cranial implant device is subgaleally implanted. The cranial implant housing also includes a pressure sensor operably connected to the cranial implant housing, which pressure sensor is configured to sense intracranial pressure (ICR). The cranial implant housing also includes at least a first controller operably connected to the pressure sensor, which first controller is configured to selectively effect the pressure sensor to sense the ICR within a cranium of the subject to generate ICP data and to transmit the ICP data to an ICP data receiver. In addition, the cranial implant housing also includes a power source operably connected or connectable at least to the first controller. Other aspects are directed to various related systems, computer readable media, and methods.

Disclosed is a compound bone plate for attaching a bone flap to a skull. The compound bone plate can include a first plate member, a second plate member, a burr hole cover, and a strut. The first plate member can be operable to be attached to the bone flap and the skull. The second plate member can be operable to be attached to the bone flap and the skull. The strut can connect the first plate member, the second plate member, and the burr hole cover.

Techniques for fabrication of implant material for the reconstruction of fractured eye orbit may include using an image processing system to analyze a set of two-dimensional images representing a three-dimensional scan of a skull of a patient, automatically detect an orbital fracture in the skull based on the set of two-dimensional images, and identify which/both of the two eye orbits containing any orbital fracture. The techniques may further include, for each of the two-dimensional images in which the orbital fracture is detected, determining a region of interest, and extracting the region of interest. The techniques may further include generating a three-dimensional reconstruction model for the fractured eye orbit, and outputting model data for generating an implant mold for the fractured eye orbit.

A method for performing a cranioplasty includes the steps of prefabricating a sonolucent craniofacial implant based upon information generated by preoperative scans, creating a cranial, craniofacial, and/or facial defect, and attaching the craniofacial implant to the cranial, craniofacial, and/or facial defect. The craniofacial implant is composed of a material that is sonolucent and exhibits attenuation of less than 6 dB/cm.

Patient-specific craniofacial implants structured for filling bone voids or planned bone voids in the cranium and face as well as for simultaneously providing soft tissue reconstruction and/or augmentation for improved aesthetic symmetry and appearance of face and skull. Pterional or temporal voids or defects generally result from a chronic skull or lateral facial deformity along with a compromised temporalis muscle or soft tissue distortion from previous surgery. When muscle and fat atrophy occurs in the pterion or temporal face, temporal hollowing deformity generally results where there would be soft tissue but for the atrophy. The patient-specific craniofacial implants with dual-purpose herein are configured to have an augmented region adjacent the temporal region of the face and cranium in order to prevent and/or correct any such temporal hollowing deformity and to utilize this newfound space to strategically embed implantable neurotechnologies for improved outcomes.

A method for performing a cranioplasty includes the steps of prefabricating a sonolucent craniofacial implant based upon information generated by preoperative scans, creating a cranial, craniofacial, and/or facial defect, and attaching the craniofacial implant to the cranial, craniofacial, and/or facial defect. The craniofacial implant is composed of a material that is sonolucent and exhibits attenuation of less than 6 dB/cm.

A cranial implant for access to a cerebral cortex includes a window member shaped and dimensioned for positioning within a dural defect to provide access through the dura such that access to the cerebral cortex is provided in a location under study. An implant body is provided having a geometry that substantially conforms to a resected portion of a patient's anatomy to which the implant body is to be secured.

The present invention relates to an acoustic window (1) suitable for implantation at an opening in a patient's skull (4), said acoustic window (1) being intended to cooperate with an external ultrasound probe (2) for the emission of ultrasound waves through the acoustic window (1), remarkable in that the acoustic window comprises a plate (11) including a plurality of through-holes (12), the distance (P) of the through-holes (12) being less than twice the wavelength of the ultrasound waves emitted by the external ultrasound probe (2).