The invention primarily relates to fastening and stabilizing tissues, implants, and/or bondable materials, such as the fastening of a tissue and/or implant to a bondable material, the fastening of an implant to tissue, and/or the fastening of an implant to another implant. This may involve using an energy source to bond and/or mechanically to stabilize a tissue, an implant, a bondable material, and/or other biocompatible material. The invention may also relate to the use of an energy source to remove and/or install an implant and/or bondable material or to facilitate solidification and/or polymerization of bondable material.

This disclosure is directed to a resilient interpositional arthroplasty implant for application into a joint to pad cartilage defects, cushion, and replace or restore the articular surface, which may preserve joint integrity, reduce pain and improve function. The implant may endure variable joint compressive and shear forces and cyclic loads. The implant may repair, reconstruct, and regenerate joint anatomy, and thereby improve upon joint replacement alternatives. The walls of this invention may capture, distribute and hold living cells until aggregation and hyaline cartilage regrowth occurs. The implant may be deployed into debrided joint spaces, molding and conforming to surrounding structures with sufficient stability so as to enable immediate limb use after outpatient surgery. Appendages of the implant may repair or reconstruct tendons or ligaments, and menisci by interpositional inflatable or compliant polymer arthroplasties that promote anatomic joint motion.

A novel hydraulic implant delivery system for introducing a hydrogel implant into a cartilage repair site is disclosed.

This invention provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by a specific fluid uptake capacity value of at least 75%, which specific fluid uptake capacity value is determined by establishing a spontaneous fluid uptake value divided by a total fluid uptake value. This invention also provides solid substrates for promoting cell or tissue growth or restored function, which solid substrate is characterized by having a contact angle value of less than 60 degrees, when in contact with a fluid. This invention also provides solid substrates for promoting cell or tissue growth or restored function, which said substrate is characterized by a substantial surface roughness (Ra) as measured by scanning electron microscopy or atomic force microscopy. The invention also provides for processes for selection of an optimized coral-based solid substrate for promoting cell or tissue growth or restored function and applications of the same.

The invention provides a device, a kit for repairing and fixing articular cartilage, and a method for the same. The device comprises a costal cartilage rod, an outer sleeve, a drilling part, and an auxiliary implantation component; the drilling part comprises a drill sleeve and a drill bit matching an inner diameter of the drill sleeve; the auxiliary implantation component comprises a cartilage rod sleeve and an auxiliary pushing element, the costal cartilage rod has a rod-shaped structure with a diameter ranging from 3 mm to 8 mm and less than an inner diameter of the cartilage rod sleeve, and the costal cartilage rod is obtained from processing of costal cartilage. The costal cartilage is selected from the group consisting of autologous costal cartilage, allogeneic costal cartilage, or xenogeneic costal cartilage. Costal cartilage is processed into a costal cartilage rod by using the device provided in the present invention.

A medical device for implantation in a hip joint of a human patient, the natural hip joint having a ball shaped caput femur as the proximal part of the femoral bone with a convex hip joint surface towards the center of the hip joint and a bowl shaped acetabulum as part of the pelvic bone with a concave hip joint surface towards the center of the hip joint. The medical device comprising; an artificial caput femur, comprising a convex surface towards the center of the hip joint. The artificial convex caput femur is adapted to, when implanted: be fixated to the pelvic bone of the human patient, and be in movable connection with an artificial acetabulum surface fixated to the femoral bone of the patient, thereby forming a ball and socket joint. The medical device further comprises a fixation element comprising a fixation surface adapted to be in contact with the surface of the acetabulum and adapted to fixate the artificial convex caput femur to at least the acetabulum of the pelvic bone.

The aim of the invention is to restore the mobility of an articular end (2) of a bone (3) of a patient by means of a reconstruction implant. This implant (1), which permits reconstruction both of bone and of cartilage, comprises a grated framework (10) and a sheet (20) made of a biological tissue material, this sheet firmly covering one face (11) of the framework, while the opposite face (12) is designed to be pressed rigidly against, and firmly joined to, the end of the bone.

A system including an instrument adapted to be manually supported and moved by a user. The instrument having a hand-held portion, a working portion movably coupled to the hand-held portion, and a plurality of actuators operatively coupled to the working portion for moving the working portion in a plurality of degrees of freedom relative to the hand-held portion. The instrument having a tracking device attached to the hand-held portion. The system including a navigation system for determining a position of the working portion relative to a target volume, and a control system in communication with the actuators to control the actuators to move the working portion relative to the hand-held portion such that the working portion autonomously follows a path defined in the control system to remove material of the target volume while the user maintains the hand-held portion in a gross position relative to the target volume.

A system and method for repairing soft tissue tears such as meniscal tears. The anchor system has a first implant connected to a length of suture. The length of suture is folded such that a tensioning limb extends from the first implant and a locking limb extends from the first implant. The anchor system also includes a second implant fixed to the locking limb and an adjustment mechanism in the length of suture between the first implant and the second implant. The tensioning limb is passed through the adjustment mechanism. This creates an adjustment loop in the length of suture extending from the adjustment mechanism through the first implant. The adjustment loop is a one-way adjustable loop for moving the first implant and second implant in relative position to each other.

A miniature bone mounted robot configured to perform minimally invasive orthopedic surgery coupled with regenerative three-dimensional bio-printing technology to restore cartilage and affected bone. The robot uses a sensor device attached to a holder affixed to the robot activated arm, to map the three-dimensional surface of the bone surface to be treated. The sensor may be a touch sensor, an optical imaging device, or another tool for mapping the bone surface. The robot shapes and prepares the bone surface and subsequently deposits a bio-ink implant in a three-dimensional pattern mimicking the original shape and depth of the articular cartilage. Because the entire procedure is conducted through the robotic platform rigidly mounted on the patients bone, there is no need for registration to preoperative three dimensional images, or for intraoperative tracking. Cell deposition based on mapping of the actual three dimensional anatomy, ensures an optimal outcome.