A method is disclosed for creating a patient-specific orthopedic implant. The method includes creating a numerical representation of an orthopedic implant design based on patient data describing an anatomical, physiological and pathological condition of a patient and simulating a characteristic of the orthopedic implant design based on the numerical representation. The method further includes selecting a patient-specific orthopedic implant design based on the simulated characteristic of the orthopedic implant design and the patient data and constructing at least one patient-specific orthopedic implant based on the selected patient-specific orthopedic implant design.

A knee prosthesis (e.g., a tibial implant or component) is disclosed. In one embodiment, the tibial implant includes a load bearing component (e.g., a tibial tray) and a support member arranged and configured to be at least partially positioned within an intramedullary canal of a patient's bone. In some embodiments, the tibial implant may also include one or more pegs positioned anteriorly on a bottom surface of the tray and one or more bridges for coupling the pegs to the support member so that loads received by the pegs are transferred to the support member via the bridge. In addition, and/or alternatively, the tibial implant may include one or more chamfers or loading zones for elongating the transition area between the support member and the bottom surface of the tibial tray to extend the area over which the load is transferred.

A medical device comprising a substantially flexible porous structure. The porous structure comprises a plurality of interlocking units. Each of the plurality of interlocking units comprises a body and at least one arm. The plurality of interlocking units is configured to have space between adjacent interlocking units when the porous structure is in a neutral configuration. The plurality of interlocking units is configured to contact the respective body and arm of adjacent interlocking units when a compressive force is applied to the porous structure, thereby restricting compression of the porous structure. The plurality of interlocking units is configured to contact the respective arms of adjacent interlocking units when an extension force is applied to the porous structure, thereby restricting extension of the porous structure.

Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating.

The invention features a glenoid (shoulder socket) implant prosthesis, a humeral implant prosthesis, devices for implanting glenoid and humeral implant prostheses, and less invasive methods of their use for the treatment of an injured or damaged shoulder.

Hard-tissue implants are provided that include a bulk implant, a face, pillars, slots, and at least one support member. The pillars are for contacting a hard tissue. The slots are to be occupied by the hard tissue. The at least one support member is for contacting the hard tissue. The hard-tissue implant has a Young's modulus of elasticity of at least 3 GPa, and has a ratio of the sum of (i) the volumes of the slots to (ii) the sum of the volumes of the pillars and the volumes of the slots of 0.40:1 to 0.90:1. Methods of making and using hard-tissue implants are also provided.

A medical implant includes a first implant body and a pre-coating covering at least a portion of an outer surface of the first implant body. The pre-coating has a negative Poisson's ratio. A method of making a medical implant includes applying a precursor material on a surface of a first implant body, the first implant body having a positive Poisson's ratio. A stimulus is applied to the precursor material, the stimulus causing the precursor material to form a coating having a negative Poisson's ratio

A build-plate with integrally-formed spinal implant constructs and a method used in forming spinal implant constructs on the build-plate and machining the spinal implant constructs formed on the build-plate to manufacture spinal implants is provided. The spinal implant constructs can be formed via additive manufacturing processes by adding material to an upper surface of the build-plate, and then the spinal implant constructs can be subjected to subtractive manufacturing processes to form the spinal implants.

A hip implant system includes an artificial acetabular cup and an artificial acetabular liner. The liner includes or consists of a metal or an alloy, and is coated at least in sections with a ceramic coating.

An artificial articulation having stable fixing means for unicompartmental knee arthroplasty is stably attached to the top of a tibia in order to permit a sliding motion of an artificial joint attached to the bottom of a femur. The artificial articulation includes an implant hat part which a curved surface structure that makes surface contact with the artificial joint attached to the bottom of the femur is formed on an upper surface thereof, and protrusions protruding by a predetermined height in a direction of the top of the tibia are formed in large numbers on a lower surface thereof, and a distally extending stem configured to be formed to protrude downward by a predetermined length from the lower surface of the implant hat part, and to be inserted into the tibia by a predetermined depth from the top of the tibia and attached thereto.