Provided are bispecific antibodies against CD3 and EGFR, the nucleic acid molecules encoding the antibodies, expression vectors and host cells used for the expression of the antibodies. The antibodies provide a potent agent for the treatment of CD3-related and/or EGFR-related diseases via modulating immune functions.

The present disclosure describes transaction-enabling systems and methods. A system can include a facility including a core task including a customer relevant output and a controller. The controller may include a facility description circuit to interpret a plurality of historical facility parameter values and corresponding facility outcome values and a facility prediction circuit to operate an adaptive learning system, wherein the adaptive learning system is configured to train a facility production predictor in response to the historical facility parameter values and the corresponding outcome values. The facility description circuit also interprets a plurality of present state facility parameter values, wherein the trained facility production predictor determines a customer contact indicator in response to the plurality of present state facility parameter values and a customer notification circuit provides a notification to a customer in response.

A storage architecture and associated usage techniques are described for providing efficient modification and use of access rights for stored data. The access rights may be associated with data stored on blockchain storage, and a separate ledger storage system may be used to provide improvements for modifying access rights for such stored data. For example, groups of data may be created and stored on blockchain storage before access to the stored data groups is made available to end users, and additional information related to those stored data groups (e.g., about their access rights) may be stored in a separate ledger storage system. When a particular user later requests access rights for one of those previously stored data groups, corresponding modifications may be quickly made to the separate ledger storage system to provide the user with substantially immediate access to that stored data group.

In one embodiment, a system for managing communication connections in a virtualization environment includes a plurality of host machines implementing a virtualization environment, wherein each of the host machines includes a hypervisor, at least one user virtual machine (user VM), and a distributed file server that includes file server virtual machines (FSVMs) and associated local storage devices. Each FSVM and associated local storage device are local to a corresponding one of the host machines, and the FSVMs conduct I/O transactions with their associated local storage devices based on I/O requests received from the user VMs. Each of the user VMs on each host machine sends each of its respective I/O requests to an FSVM that is selected by one or more of the FSVMs for each I/O request based on a lookup table that maps a storage item referenced by the I/O request to the selected one of the FSVMs.

Various embodiments comprise systems and methods to sample data outputs of a data pipeline. In some examples, data monitoring circuitry monitors the data pipeline wherein the data pipeline receives an input data set, processes the input data set, and responsively generates and transfers an output data set. The data monitoring circuitry ingests the output data set, determines an amount of available computing resources, and selects an amount of the values from the output data set based on the amount of available computing resources. The data monitoring circuitry generates a quality score for the selected values based on a data quality, generates a confidence score based on the amount of the selected values, and reports the quality score and the confidence score.

An example method for mapping data can include: generating a user interface configured to enable a user to create a data element of a mapping specification, wherein the mapping specification includes a spreadsheet having a plurality of data fields; allowing for dragging of the data element onto the user interface and multi-selection of the data element with other data elements; allowing for dropping of the data element into a desired location of the user interface and the multi-selection of the data element; storing the data element in a temporary schema independent from a database schema of the data warehouse; and enabling the user to associate the data element with one or more physical data elements in the database schema.

Methods, apparatuses, or computer program products provide for triggering component workflows within a multi-component system. An update to one or more component metadata records of a component metadata vector associated with a first component identifier may be received. The component metadata vector may include a plurality of records. Each record of the plurality of records may include a unique component metadata record identifier and a component metadata value. The component metadata vector associated with the first component identifier may be traversed after updating the one or more component metadata records. Based at least in part on detecting a component metadata condition associated with a component workflow trigger associated with the first component identifier, a first component workflow action of a first component workflow action series comprising a plurality of component workflow actions may be executed. Furthermore, a component workflow trigger notification may be transmitted to a first computing device.

Embodiments of the present disclosure may provide a data protection system that performs identification of errors from queries on a database. The data protection system can further identify corrupted data from additional errors, are difficult to detect, and occur between layers of data in the database system. The data protection system can perform corrections of the error data by rebuilding database data or removing the corrupted data.

A method for use in a storage system is disclosed, comprising: receiving, at a first server in the storage system, a given block layer request for reservation of a storage resource, by the first server, an identifier corresponding to the given block layer request; performing a search of a database to detect whether the given block layer request has been completed, the search being performed by the first server, the search being performed based on the identifier corresponding to the given block layer request; when the database indicates that the given block layer request has not been completed: completing the given block layer request and transmitting a notification that the given block layer request is completed; and when the database indicates that given block layer request has been completed, re-transmitting a notification that the given block layer request is completed.

A device configured to receive a first current status for a user account from a provisioning service device. The device is further configured to query a status log using to determine a second current status of the user account. The device is further configured to compare the first current status for the user account from the provisioning service device to the second current status of the user account in the status log, to determine the first current status for the user account does not match the second current status of the user account, and to update one of the status log and the provisioning service device in response to determining that the first current status for the user account does not match the second current status of the user account.