An esophageal stent configured to span a stricture may include a tubular body configured to shift between a delivery configuration and a deployed configuration, the tubular body having a first end and a second end. In the deployed configuration: the tubular body defines a first flange portion, a second flange portion, and a saddle portion extending from the first flange portion to the second flange portion; the tubular body further defining an overall longitudinal length extending from the first end to the second end; the first flange portion has a first outer radial extent, and the second flange portion has a second outer radial extent; the first outer radial extent and the second outer radial extent are greater than an outer radial extent of the saddle portion; and a longitudinal length of the saddle portion is at least 50% of the overall longitudinal length of the tubular body.

A stent for use in a medical procedure having opposing sets of curved apices, where the curved section of one set of apices has a radius of curvature that is greater than the curved section of the other set of apices. One or more such stents may be attached to a graft material for use in endovascular treatment of, for example, aneurysm, thoracic dissection, or other body vessel condition.

A stent graft comprises a plurality of wavy rings sequentially arranged in a spaced manner, and membranes fixed to the plurality of wavy rings, wherein the stent graft comprises, in a circumferential direction, at least one keel region and a non-keel region connected to the keel region, the keel region having an axial shortening rate that is less than that of the non-keel region, and the axial shortening rate of the keel region is 10-40%. The stent graft can be bent in all directions, and the keel region on the stent graft can provide a sufficient amount of an axial support force for the stent.

A vascular shunt frame with improved apposition including a main body tube; at least one end of the main body tube is provided with a sealing covering; the sealing covering is provided with a main blood flow opening; a shaping component is disposed at the edge of the main blood flow opening. When the main body stent is inserted into the main blood flow opening of the main body tube, the shaping component can be closely attached to the outer surface of the main body stent, such that the sealing covering closely fits the outer surface of the main body stent to prevent endoleaks. The present disclosure also provides a vascular stent provided with an apposition-improved vascular shunt frame.

Various embodiments of an implant delivery systems including at least one removable actuator to reshape a valve annulus are described. The systems may use the removable actuator to customize annular reshaping at a treatment site and withdraw the actuator from the treatment site following custom reshaping to provide a low profile annuloplasty implant.

The disclosure provides various embodiments of prostheses and delivery systems to permit an interventional cardiologist to create shunts between various blood vessels. Moreover, the disclosed shunts can be used to shunt between various hollow organs, as set forth in the present disclosure.

A percutaneous heart valve prosthesis including a collapsible valve body frame has a first end and a second end. The valve body frame is formed by a plurality of sub-frame members, each sub-frame member having a general form of a diamond with acute-angled vertices and oblique-angled vertices, wherein adjacent sub-frame members are joined at the oblique-angled vertices. A flexible skirt made from pericardial material extends around a periphery of the valve body frame. A one-way valve including a plurality of flexible valve leaflets is positioned within the valve body frame. The first end of the valve body frame is sized to pass through a valve orifice associated with a heart valve to be replaced and the second end of the valve body frame is sized so as not to pass through a valve orifice.

A luminal endoprosthesis assembly (1) at least partially delimits a prosthesis lumen (2), for implantation in an anatomical structure (3) that at least partially defines at least one cavity (4) and includes at least one pathological portion (13). The luminal endoprosthesis (1) has two or more layers (5, 6, 7). At least one layer (5, 6, 7) includes a threadlike element (8) forming an armor (9). The luminal endoprosthesis (1) includes an anchoring portion (10) for anchoring to an anatomical portion (11) of the walls of the cavity (4) of the anatomical structure (3), and a working portion (12) for facing the pathological portion (13) of the anatomical structure (3). The two or more layers (5, 6, 7) are separated from each other in the working portion (12) of the luminal endoprosthesis (1), avoiding connecting elements between one layer (5, 6, 7) and at least one adjacent layer.

A compressible and expandable stent assembly for implantation in a body lumen such as a mitral valve, the stent assembly including at least one stent barrel that is shaped and sized so that it allows for normal operation of adjacent heart structures. One or more stent barrels can be included in the stent assembly, where one or more of the stent barrels can include a cylinder with a tapered edge.

Disclosed are a stent delivery and release device and a stent delivery and release system. The stent delivery and release device (20) includes a stent proximal end release assembly provided at a proximal end of the stent delivery and release device, a guide head provided at a distal end of the stent delivery and release device, and a control member, wherein an external stent is configured to be loaded between the guide head and the stent proximal end release assembly; a proximal end of the control member is connected to the stent proximal end release assembly, and at least part of a distal end of the control member is wound around the stent and is detachably connected to the guide head; and the stent proximal end release assembly folds or releases the stent by controlling the axial length of the control member.