A composition for use in cooling therapy and treatment of chemically induced alopecia (CIA), said composition containing a reactive oxygen species (ROS) inhibitor.

Described embodiments provide systems and methods for managing the temperature of an item that includes a first flap portion and a second flap portion defining between them a first pouch containing substance; a third flap portion and the second flap portion defining between them a second pouch containing substance; a first portion of a fastener attached to the front side of the first flap portion; a first complementary portion of the fastener attached to the obverse side of the second flap portion; a second complementary portion of the fastener attached to the obverse side of the third flap portion.

A scalp cooling apparatus, method, and system that may include an inner scalp cap, an intermediate scalp covering, and an outer scalp cap. The inner scalp cap may be fluidly coupled to a cooling device, that would allow a cooling fluid to traverse the fluid chambers within a set of sections of the inner scalp cap. The inner scalp covering can be constructed of a thermally conductive material. The intermediate scalp covering can be constructed of a thermally neutral material. The outer scalp covering can be constructed of a thermally resistant material. The outer scalp covering may have a first securing mechanism, and a second securing mechanism, that allow the outer scalp covering to be dynamically adjusted and secured against a patient's scalp via the first securing mechanism and the second securing mechanism. The inner scalp cap may be created from a scan of a patient's head, that can then be utilized as an interpolated parametric model may be utilized to generate an output file.

A scalp cooling apparatus, method, and system that may include an inner scalp cap, an intermediate scalp covering, and an outer scalp cap. The inner scalp cap may be fluidly coupled to a cooling device, that would allow a cooling fluid to traverse the fluid chambers within a set of sections of the inner scalp cap. The inner scalp covering can be constructed of a thermally conductive material. The intermediate scalp covering can be constructed of a thermally neutral material. The outer scalp covering can be constructed of a thermally resistant material. The outer scalp covering may have a first securing mechanism, and a second securing mechanism, that allow the outer scalp covering to be dynamically adjusted and secured against a patient's scalp via the first securing mechanism and the second securing mechanism. The inner scalp cap may be created from a scan of a patient's head, that can then be utilized as an interpolated parametric model may be utilized to generate an output file.

A medical cooling device and a method for operating the same are provided.

A heating/cooling therapy treatment pad system incorporates a plurality of therapy pads that can be coupled together by connectors and attachments to form an integrated therapy pad assembly. The thermal pads have pouches for receiving thermal inserts that may be heated or chilled. The thermal inserts may be cylindrical in shape and there may be thermal insert gaps, or spaces between the pouches to enable better conformability of the therapy pad to a person's body, such as around the neck. The heating/cooling therapy treatment pad system may include a neck therapy pad, spine therapy pad, head and face therapy pads, shoulder therapy pad, lumbar therapy pad, armpit thermal therapy pad and a thermal therapy pad vest. The system of pads interconnect to provide tailored thermal therapy to multiple areas of a user's body and may be used to effectuate rapid cooling and in particular for those suffering from heat exhaustion.

Disclosed herein is a method to enable a user to use a hypothermia system to cool a body part involved in cancer therapy or in brain trauma. The method enables the user to operate the hypothermia system by her- or himself and still be mobile. The hypothermia system comprises a conformal cap system, a thermally conductive liquid located between the body part to be cooled and the cap system, thermal transfer fluids, phase change materials, thermally insulated cooler, physical measuring devices, mechanical and electrical components, a smart user interface device, a battery, and an uninterruptible power controller. The method allows a user to control the rate of and temperature of cooling down the body part, exhibits parameters associated with the process of cooling the body part, provides alerts if necessary, is portable and entirely self-managed. The hypothermia device is in communication with and can be controlled by an application installed on a smart device, such as a phone. The method of using the hypothermia system can help to eliminate hair loss caused by the side effects of certain chemotherapy treatments or to reduce the metabolic rate of ischemic tissue to prevent or minimize the severity of swelling.

Provided is a neuroprotection apparatus including a scalp temperature measurement acquisition device for acquiring scalp temperature measurements at a plurality of locations on a patient's scalp during an induced hypothermia and a neuroprotection processor for processing the scalp temperature measurements for determining real time patient temperature information for display on a human head image on a display device during the induced hypothermia.

A heat exchanger, and method of manufacture of a heat exchanger configured to be placed into contact with an object to regulate the temperature of the object. The heat exchanger comprises a layer of material defining a passage through which a heat transfer fluid may flow. The material layer has a first side for contact with the object; and a second side which, in use, will face away from the object. The first side has a relatively high coefficient of thermal conduction. The second side has a relatively low coefficient of thermal conduction compared to the first side.