A system for cooling a head of a user to mitigate or prevent drug-induced hair-loss, including a hat, which includes an exterior layer, an interior layer, with an inflatable chamber therebetween, the inflatable chamber being functionally associated with an inflation pump. The hat includes a cooling assembly, reversibly attachable to the interior layer and including a housing defining pockets having cooling pads therein. Each cooling pad comprising a phase-changing-material adapted to obtain a temperature lower than 20 C. and to retain that temperature. A sensor is adapted to sense an environmental condition within the hat. A controller is adapted to receive input from the sensor, and to provide a notification when the sensed environmental condition is outside of a specific range. When the hat is donned by the user, the inflatable chamber is inflated sufficiently to ensure that the cooling assembly engages the scalp of the user.

Medical devices for inducing hypothermia are disclosed. Induced hypothermia is a treatment used to reduce secondary complications caused by reduced oxygen and blood flow during traumatic injuries and surgeries. However, induced hypothermia also has negative side effects such as shivering and lowered immune system. These devices incorporate Highly-Oriented Pyrolytic Graphite (HOPG) for solid conduction to lower the temperature at targeted locations on and inside the body. The benefits of incorporating HOPG include: highly efficient heat conduction, flexibility in design and manufacture, reduction of dependence on inefficient and unstable fluid-filled implants and catheters, and anti-thrombotic effects.

A cold cap adapted for connecting to a chiller unit for circulating chilled fluid through the cap. The cap is formed from at least three layers of material which are sealingly attached around their periphery so as to form a cooling fluid chamber, wherein the cap is configured to apply compression and cooling to the scalp.

A blood flow restricting apparatus is provided. The blood flow restricting apparatus can include a frame element configured to be securable to a user's head. At least one cooling pad can be operatively arranged with the adjustable frame element and configured to be arranged over a defined anatomic location including at least one of a pair of supratrochlear arteries, a pair of supraorbital arteries, a pair of temporal arteries, and a pair of occipital arteries of the user's head when the frame element is secured to the user's head. A pressurizing mechanism can be operatively arranged with the at least one cooling pad and capable of pressing the at least one cooling pad against the defined anatomic location to restrict blood flow to each of the targeted arteries while simultaneously cooling the defined anatomic location to induce hypothermic induced vasoconstriction.

A blood flow restricting apparatus is provided. The blood flow restricting apparatus can include a frame element configured to be securable to a user's head. At least one cooling pad can be operatively arranged with the adjustable frame element and configured to be arranged over a defined anatomic location including at least one of a pair of supratrochlear arteries, a pair of supraorbital arteries, a pair of temporal arteries, and a pair of occipital arteries of the user's head when the frame element is secured to the user's head. A pressurizing mechanism can be operatively arranged with the at least one cooling pad and capable of pressing the at least one cooling pad against the defined anatomic location to restrict blood flow to each of the targeted arteries while simultaneously cooling the defined anatomic location to induce hypothermic induced vasoconstriction.

A head-cooling cap for controlling swelling caused by any head injury is provided. The head-cooling cap includes a flexible, preferably adjustable cap-shaped main body with a plurality of inner cavities containing a cooling substance. The main body can be built in a three-dimensional cap shape or, alternatively, be deformable to adopt a three-dimensional cap shape. When the head-cooling cap is placed on a user's head, the cooling substance, which has been kept at an adequate cold temperature, will cool the head and control any swelling caused by a traumatic head injury. When not placed on a user's head, the head-cooling cap can be conveniently stored in a refrigerator or freezer to prepare it for further use.

Devices, systems, and methods herein relate to cooling a head of a patient. These systems and methods may comprise a cooling cap assembly comprising a heat exchanger configured to be wrapped around a head of a patient and a compression assembly releasably coupled to the heat exchanger. The compression assembly may comprise an enclosure and an inflatable member coupled to an internal surface of the enclosure. When coupled, the inflatable member may be positioned between the enclosure and the heat exchanger. The heat exchanger may be separate from and moveable relative to the inflatable member.

Devices, systems, and methods herein relate to cooling a head of a patient. These systems and methods may comprise a cooling cap assembly comprising a heat exchanger configured to be wrapped around a head of a patient and a compression assembly releasably coupled to the heat exchanger. The compression assembly may comprise an enclosure and an inflatable member coupled to an internal surface of the enclosure. When coupled, the inflatable member may be positioned between the enclosure and the heat exchanger. The heat exchanger may be separate from and moveable relative to the inflatable member.

The disclosed devices and methods cool the nasal and/or oral cavity and perioral area, which in turn triggers a positive sensory reflex response to the brain leading to improvement of abnormally regulated cerebral vasomotor (brain arterial) tone which is thought to be the primary trigger factor for migraine headaches. Cooling is applied temporarily (10 to 30 minutes) to the inside of either or both nostrils. In some examples, the device is a single-use cooling bullet made from plastic (or other materials), has a conical, egg, nasal, oval, or other suitable shape and fits tightly to the inside of either nostril. The bullet may contain a nontoxic coolant (i.e., propylene glycol), water or other coolant which is kept at a cold state (e.g. 3-6 degrees Celsius below normal body temperature).