A method and apparatus in accordance with a particular embodiment of the present invention includes applying adhesive onto skin of a human subject. An applicator is then brought into contact with the adhesive such the adhesive is disposed between the applicator and the subject's skin. The applicator is activated to cool a tissue region via the subject's skin, via the heat-transfer surface of the applicator, and via the adhesive. While the tissue region cools, the adhesive also cools, thereby reversibly strengthening adhesion between the subject's skin and the heat-transfer surface and forming a strong bond therebetween. The strengthened adhesion inhibits any movement of the applicator relative to the skin. After cooling the tissue region, the adhesive is warmed, thereby weakening the adhesion which allows the heat-transfer surface of the applicator to be easily separated from the skin.

A therapeutic collar comprising an elongate body made from a flexible material for extending around at least a portion of the neck of a patient. The body has a length approximating the circumference of the neck, two thermoelectric devices for overlying two carotid arteries in the neck and two thermoelectric devices for overlying of two vertebral arteries in the neck when the elongate body is secured around the neck of the patient. At least one cooling tube is carried by the elongate body and extends in the vicinity of each of the thermoelectric devices for removing heat from the thermoelectric devices.

A therapeutic collar comprising an elongate body made from a flexible material for extending around at least a portion of the neck of a patient. The body has a length approximating the circumference of the neck, two thermoelectric devices for overlying two carotid arteries in the neck and two thermoelectric devices for overlying of two vertebral arteries in the neck when the elongate body is secured around the neck of the patient. At least one cooling tube is carried by the elongate body and extends in the vicinity of each of the thermoelectric devices for removing heat from the thermoelectric devices.

Provided herein is a stimulation device, system and method for therapeutic treatment of a condition or disease. In various aspects, the device may include one or more modules for low temperature, vibration, pressure, or ultrasound stimulation, operably connected to a contact tip; a data logging module; and a wireless communication module. Also provided is a system including such device and a remote server. Additionally, a method of treatment using such device or system is provided.

Systems and methods for managing patient temperature are disclosed. Temperature management systems that are suitable for an out-of-hospital setting are disclosed. Temperature management systems having a low power requirement are disclosed. Temperature management systems that include a disposable, single-use reservoir are disclosed.

Provided herein are methods and devices for treatment of migraines or other headaches. In various aspects, one illustrative method may include steps of applying a contact tip of a device to an external tissue in an area of the skull of a subject, and administering a low temperature stimulation for a period of time. The contact tip of the device may be operably connected with a case and a low temperature stimulation module such that the contact tip provides low temperature stimulation. Various other features may also be included.

A cervical collar that facilitates therapeutic hypothermia is provided and includes an outer shell having a front portion and a back portion fixedly coupled to the front portion on one side and removably coupled to the front portion on an opposite side. A fastening device removably couples the back portion to the front portion on the opposite side. At least one cooling device is provided on an interior of the outer shell to induce hypothermia in a patient. A sensor is provided that measures a physical characteristic of the patient.

Methods and systems for thermoregulation of injured tissue, medical specimens and other perishable materials are disclosed. Thermoregulation systems can comprise a thermoelectric device comprising a thermoelectric element within a flexible sleeve such that the sleeve can be applied circumferentially within an orthopedic positioner. Methods for shipping medical specimens under precise temperature control are disclosed by actively regulating the temperature within containers and at the surface of the specimen. Methods for treating injured tissue that demonstrate increased precision and control are disclosed.

A system that selectively controls temperature within a device such as a neck/head wrap is disclosed. The system can include a pump system having a reservoir that holds a liquid, an element that regulates temperature of the liquid within the reservoir; a pump that draws the liquid from the reservoir; and a distribution manifold attached to the pump hose that receives and distributes the liquid to at least two devices (e.g., cervical collars). The system is also equipped to be selectively monitored, for example, via a smartphone, tablet or computer.

A medical device and method used for patient temperature management, wherein the device is designed to cool the patient's head and blood flow to the head and neck including the two carotid and the two vertebral arteries of a patient after trauma in order to prevent inflammation and reduce swelling in the brain. It is portable with a rapid cooling capability feature, does not require an ICU setting, eliminates certain complications that could affect the patient otherwise, and can be quickly and easily placed on the patient with little training or expertise.