An ophthalmic laser system for generating a first beam at a first wavelength on a first beam path and a second beam at a second wavelength on a second beam path, and directing optics to selectively direct the first beam or the second beam to a treatment beam path. The ophthalmic laser system incorporates a reflex coaxial illuminator comprising a reflex mirror movable on an axis from a position out of the treatment beam path to a position in the treatment beam path to direct illumination into an illumination path coaxial with the treatment beam path. The reflex mirror is adapted to transmit a beam that follows the second beam path.

Disclosed is a patient interface for affixment on onto a patient eye, said patient interface including: a negative-pressure cavity designed for fluidic coupling to the patient eye; a first negative pressure interface with a first negative pressure aperture for fluidically coupling the negative-pressure cavity to a negative-pressure device to charge the negative pressure cavity with a negative pressure; a second negative pressure interface with a second negative pressure aperture for fluidically coupling the negative-pressure cavity to the negative-pressure device to charge the negative cavity with a negative pressure;
wherein the first negative pressure aperture and the second negative pressure aperture are arranged in a wall of the negative pressure cavity separate from and in close vicinity to each other.

A focusing optical system for a UVL-LVC system with a UV laser source and a scanning system that focuses a laser in a focal field and a lens assembly with a convergent focal field. The invention further includes a planning unit that generates planning data for a UVL-LNC system with a UV laser source, a scanning system, a focusing optical system, and a control unit for controlling the UVL-LVC system while taking into consideration planning data, wherein the planning unit takes into consideration geometry losses, Fresnel losses, and/or a spatial extension of laser radiation on a working surface while calculating the planning data, and the planning unit has an interface that provides the planning data. Finally, the invention includes a UVL-LVC system with a UV laser source, a scanning system, a focusing optical system according to the invention, a planning unit according to the invention, and a control unit.

A system (20) includes a radiation source (48) and a controller (44). The controller is configured to define a treatment zone (88) on a capsule (86) of an eye (25) of a subject (22), and to form an opening (96) in the capsule, subsequently to defining the treatment zone, by irradiating multiple target regions (94) within the treatment zone in an iterative process that includes, during each one of multiple iterations of the process, acquiring an image (98) of at least part of the capsule, designating one of the target regions based on the acquired image, and causing the radiation source to irradiate the designated target region. Other embodiments are also described.

A method for laser eye surgery that accommodates patient movement includes: generating a first and a second electromagnetic radiation beam, the second beam configured to modify eye tissue; propagating the first beam to a scanner along a an optical path length that changes in response to eye movement; focusing the first beam to a first focal point within the eye; scanning the first focal point at different locations within the eye; propagating a portion of the first beam reflected from the first focal point location back along the variable optical path to a sensor; generating an intensity signal indicative of the intensity of the portion of the reflected first beam; propagating the second beam to the scanner along the variable optical path; focusing the second beam to a second focal point and scanning the second focal point to create an incision in the cornea of the eye.

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method of treating an ocular disease of a subject having an implanted intraocular lens (IOL) includes determining visual needs of a subject that are associated with an ocular disease of the subject determining a pattern of a plurality of pulses of radiation to apply, by refractive index writing, and applying the plurality of pulses of radiation to the one or more selected areas of the IOL.

A laser system that includes a laser source emitting a laser beam along an axis and a keratometer. The keratometer includes a first set of individual light sources that are equally spaced from one another along a first ring and that direct a first light toward an eye and a second set of individual light sources that are equally spaced from another along a second ring and direct a second light toward the eye, wherein the first ring and said second ring are co-planar and concentric with one another about the axis. The laser system includes a telecentric lens that receives the first light and second light reflected off of the eye and a detector that receives light from the telecentric lens and forms an image. The laser system also includes a processor that receives signals from said detector representative of the image and determines an astigmatism axis of the eye based on the signals.

An optical system for a laser therapy instrument for the application of laser radiation on and in the eye, includes a femtosecond laser, an objective. The objective or at least one lens or lens group of the objective is shiftable in the direction of the optical axis being intended for shifting of the focus position from the region of the cornea to the region of the crystalline lens and vice versa. The optical system may include at least two optical assemblies designed for the axial variation of the focus of the therapeutic laser radiation, with the focus variation range Δz differing between the individual assemblies and a changing device, designed for the insertion of any one of these assemblies into the therapeutic laser beam path at a time.

A laser eye surgery system includes a laser to generate a laser beam. A spatial measurement system generates a measurement beam and measure a spatial disposition of an eye. A processor is coupled to the laser and the spatial measurement system, the processor comprising a tangible medium embodying instructions to determine a spatial model of the eye in an eye coordinate reference system based on the measurement beam. The spatial model is mapped from the eye coordinate reference system to a machine coordinate reference system. A laser fragmentation pattern is determined based on a plurality of laser fragmentation parameters. The laser fragmentation pattern and the spatial model is rotated by a first rotation angle such that the spatial model is aligned with the reference axis of the machine coordinate reference system and the rotated laser fragmentation pattern is aligned with the corneal incision.

A system for short pulse laser eye surgery and a short pulse laser system, in which a beam guidance device passes through a corresponding articulated arm, and through an applicator head and a microscope head of the system, which is movable in a three-dimensional volume both independently of one another as well as connected to each other. The system also includes, an easy-to-use patient interface with a one-piece contact element, a computer program product for methods of the incision guidance and sequentially operating referencing methods with patient interfaces containing markings.