Systems and methods of treating meibomian and sebaceous gland dysfunction. The methods include reducing oxygen concentration in the environment of one or more dysfunctional meibomian and sebaceous glands, thereby restoring a hypoxic status of one or more dysfunctional meibomian and sebaceous glands. The reducing of the oxygen concentration is accomplished by restricting blood flow to the one or more dysfunctional meibomian and sebaceous glands and the environment of one or more dysfunctional meibomian sebaceous glands. The restricting of the blood flow is accomplished by contracting or closing one or more blood vessels around the one or more dysfunctional meibomian or sebaceous glands. The methods also include giving local or systemic drugs that lead to the generation of hypoxia-inducible factors in one or more dysfunctional meibomian and sebaceous glands.

An ophthalmic device (1) for treating eye tissue (6) using laser pulses comprises a projection optical unit (12) for focussed projection of the laser pulses and a scanning device (2), with a movable mirror (20), arranged downstream from the projection optical unit (12), for deflecting the laser pulses projected by the projection optical unit (12) in at least one deflection direction. The ophthalmic device (1) moreover comprises a drive system (200) configured to displace the mirror (20) in parallel. The parallel displacement of the mirror (20) renders it possible to displace the focus of deflected laser pulses in the projection direction and therefore correct image field curvatures caused by the scanning device (2) arranged downstream from the projection optical unit (12) and, for example, image the deflected laser pulses in focus onto a plane.

A method to selectively permeabilize and/or fragmentize cells. A structure comprising a material and particles able to absorb electromagnetic radiation and cells are brought at close distance from each other. Part of the particles embedded in the structure are exposed to the free surface of the structure. The structure and, in particular, the particles in the structure are irradiated with electromagnetic radiation to selectively permeabilize and/or fragmentize the cells. Furthermore, the disclosure relates to a structure for use in a photothermal process to selectively permeabilize and/or fragmentize cells.

A system to provide high pressure air to the eye during ocular surgery. The system has an air tube, a piece 1, a piece 2 and a plurality of adjustable aperture. Piece 1 has a plurality of piece 1 air feeding tubes, a piece 1 adjustable apertures and a plurality of air ejecting nozzles. Piece 2 comprises a piece 2 air feeding tubes, a piece 2 adjustable aperture, a diameter controlled adjustable aperture and a plurality of valves. Both piece 1 and piece 2 are used separately or simultaneously. Piece 1 is used laterally and piece 2 is used vertically. A humidifies high pressure air is provided to piece 1 and piece 2 air feeding tubes by an air source. The high pressure air provided is humidified controlled high pressure air.

A system and process for treating retinal diseases includes passing a plurality of radiant beams, i.e., laser light beams, through an optical lens or mask to optically shape the beams. The shaped beams are applied to at least a portion of the retina. Due to the selected parameters of the beamspulse length, power and duty cyclethe beams can be applied to substantially the entire retina, including the fovea, without damaging retinal or foveal tissue, while still attaining the benefits of retinal phototherapy or photostimulation.

A process for safely providing retinal phototherapy includes generating first and second light beams of a different wavelength. The first and second light beams are applied to a retinal pigment epithelium (RPE) and choroid of an eye. The amount of light reflected from the eye from the first light beam and the second light beam is measured, such as using a reflectometer. A level or concentration of the melanin within the eye is calculated using the measured amount of light reflected from the eye from the first and second light beams. When the content or density of melanin in the RPE exceeds a predetermined amount, one or more treatment parameters of the retinal phototherapy is adjusted.

A system for correcting chromatic aberrations in an eye includes a diagnostic system configured to provide aberration data regarding a degree of chromatic aberration within an eye; a laser system; and a processing circuit configured to determine a diffractive lens profile to be applied to corneal tissue of the eye based on the aberration data and a desired correction of the chromatic aberration within the eye; and control operation of the laser system to apply the diffractive lens profile to the corneal tissue.

A system and process for treating retinal diseases includes passing a plurality of radiant beams, i.e., laser light beams, through an optical lens or mask to optically shape the beams. The shaped beams are applied to at least a portion of the retina. Due to the selected parameters of the beamspulse length, power and duty cyclethe beams can be applied to substantially the entire retina, including the fovea, without damaging retinal or foveal tissue, while still attaining the benefits of retinal phototherapy or photostimulation.

Images of a patient's eye can be imaged and the images processed to detect and track floaters within the patient's eye. The floater detection and tracking can be used to identify characteristics of the floaters as well as possibly perform laser treatment of the floaters.

A method for forming an incision in an eye, the method including performing a first pass of a first laser beam along a path within an eye, wherein after completion of the first pass there exists a residual uncut layer at an anterior surface of a cornea of the eye. The method further including performing a second pass of a second laser beam only along a portion of the path that contains the residual uncut layer, wherein after completion of the second pass, the residual uncut layer is transformed into a full complete through surface incision.