An equatorial anthropic radiation source and a method of making an equatorial anthropic radiation source are described. The radiation source is useful in diagnostic imaging applications in healthcare or other industries (e.g. computerized three-dimensional segmental imaging; Crompton scattering imaging techniques; radiation detector check and calibration, in particular CdZnTe detectors commonly used in medical imaging).

The invention relates to a radioisotope generator (1) comprising an eluent reservoir (2) and a chromatographic column (3) connected to one another by a first eluent duct (4), characterized in that it comprises a second duct (7) and a valve (8) connected said second duct (7) to the first eluent duct and the first eluent duct, said valve (8) having a first position where the second duct (7) communicates with the first eluent duct (4) and a second position where the second duct (7) communicates with the first eluent duct (4), said second duct (7) having a bypass segment (9) for a predetermined eluent volume.

The invention relates to a radioisotope generator (1) comprising an eluent reservoir (2) and a chromatographic column (3) connected to one another by a first eluent duct (4), characterized in that it comprises a second duct (7) and a valve (8) connected said second duct (7) to the first eluent duct and the first eluent duct, said valve (8) having a first position where the second duct (7) communicates with the first eluent duct (4) and a second position where the second duct (7) communicates with the first eluent duct (4), said second duct (7) having a bypass segment (9) for a predetermined eluent volume.

Provided is a target plate for radioisotope production that has sufficient durability and sufficient heat resistance for use in radioisotope production and that is capable of reducing the extent of radioactivation. In a target plate for radioisotope production, a support substrate, which supports a target, includes a graphite film(s). The thermal conductivity in a surface direction of the graphite film(s) is 1200 W/(m.Math.K) or greater, and the thickness of the graphite film(s) is 0.05 μm or greater and 100 μm or less.

Provided is a target plate for radioisotope production that has sufficient durability and sufficient heat resistance for use in radioisotope production and that is capable of reducing the extent of radioactivation. In a target plate for radioisotope production, a support substrate, which supports a target, includes a graphite film(s). The thermal conductivity in a surface direction of the graphite film(s) is 1200 W/(m.Math.K) or greater, and the thickness of the graphite film(s) is 0.05 μm or greater and 100 μm or less.

An equatorial anthropic radiation source and a method of making an equatorial anthropic radiation source are described. The radiation source is useful in diagnostic imaging applications in healthcare or other industries (e.g. computerized three-dimensional segmental imaging; Crompton scattering imaging techniques; radiation detector check and calibration, in particular CdZnTe detectors commonly used in medical imaging).

The present invention comprises: an electron beam accelerator (2); a container (4) housing a raw material (3) for radioactive nuclide production, said raw material including molybdenum 100; a heating device (5) that heats the raw material (3) for radioactive nuclide production; an adsorbent (81) that adsorbs technetium compounds including technetium 99m generated by the heated raw material (3) for radioactive nuclide production; an eluent supply device (10) that supplies an eluent (L1) that causes elution of the technetium compound adsorbed to the adsorbent (81); and a drug recovery unit (13) that recovers the eluent (L2).

The present invention comprises: an electron beam accelerator (2); a container (4) housing a raw material (3) for radioactive nuclide production, said raw material including molybdenum 100; a heating device (5) that heats the raw material (3) for radioactive nuclide production; an adsorbent (81) that adsorbs technetium compounds including technetium 99m generated by the heated raw material (3) for radioactive nuclide production; an eluent supply device (10) that supplies an eluent (L1) that causes elution of the technetium compound adsorbed to the adsorbent (81); and a drug recovery unit (13) that recovers the eluent (L2).

A method includes sterilizing a column assembly including a column having a parent radionuclide contained therein with a sterilizer. The method further includes transferring the column assembly from the sterilizer to a first clean room environment, transferring the column assembly from the first clean room environment to a second clean room environment, and collecting a sterility test sample from the column assembly within the second clean room environment.

Systems and methods for sterilizing a column assembly including a column having an interior containing a retaining media and a parent radionuclide retained by the retaining media, an inlet port in fluid communication with the interior of the column, and an outlet port in fluid communication with the interior of the column. The method includes sealing at least one of the inlet port and the outlet port to form a sealed column assembly such that fluid communication with the column interior though both the inlet port and the outlet port is prevented, and sterilizing the sealed column assembly to form a terminally-sterilized column assembly.